Zobrazeno 1 - 10
of 52
pro vyhledávání: '"David I, Vernon"'
Publikováno v:
Photochemistry and Photobiology. 69:390-396
Three novel substituted zinc (II) phthalocyanines (one anionic, one cationic and one neutral) were compared to two clinically used photosensitizers, 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (m-THPC) and polyhematoporphyrin (PHP), as potential agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305feac7d3b8e02825466f6856453d82
https://doi.org/10.1111/j.1751-1097.1999.tb03303.x
https://doi.org/10.1111/j.1751-1097.1999.tb03303.x
Publikováno v:
Photochemistry and Photobiology. 69:360-363
— 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin (m-THPC, Foscan) is an extremely powerful photosensitizer showing up to 200 times the photodynamic activity of Photofrin in patients, in terms of drug/light dose. The influence of treatment conditions on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86a119a52977712a4cfac081e00a0c98
https://doi.org/10.1111/j.1751-1097.1999.tb03299.x
https://doi.org/10.1111/j.1751-1097.1999.tb03299.x
Publikováno v:
Photochemistry and Photobiology. 73:39-46
Two distinct photodynamic therapy-resistant variants of the murine radiation-induced fibrosarcoma (RIF) cell line have been isolated. One strain displayed relative resistance over the parental RIF-1 strain to treatment with the porphyrin-based compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224a1bfca3a7f990d0c24ffae5df7eda
https://doi.org/10.1562/0031-8655(2001)0730039iocrta2.0.co2
https://doi.org/10.1562/0031-8655(2001)0730039iocrta2.0.co2
Autor:
Stanley B. Brown, Andrew Holroyd, David I. Vernon, Kristian Berg, Odrun A. Gederaas, Johan Emelian Moan
Publikováno v:
Photochemistry and Photobiology. 73:164-169
The transport mechanisms of 5-aminolevulinic acid methyl ester (5-ALA-ME) have been studied in a human adenocarcinoma cell line (WiDr) by means of 14[C]-labeled 5-ALA-ME. The transport was found to be partly Na+ dependent, while the extracellular Cl-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15291701a87fbc45e8b45d99cbc5049
https://doi.org/10.1562/0031-8655(2001)0730164aameto2.0.co2
https://doi.org/10.1562/0031-8655(2001)0730164aameto2.0.co2
Publikováno v:
Photochemistry and Photobiology. 75:392-397
We have synthesized a series of symmetrical phenothiazines in which the methyl groups of methylene blue have been substituted by longer alkyl chains. Intrinsic photosensitizing ability was not altered by increasing the chain length. However, in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef9cf7ef8edc88a05dad5cbb959f6ea
https://doi.org/10.1562/0031-8655(2002)0750392ivpaoa2.0.co2
https://doi.org/10.1562/0031-8655(2002)0750392ivpaoa2.0.co2
Autor:
Johanna T. H. M. van den Akker, Stanley B. Brown, Henricus J. C. M. Sterenborg, Laurens Groenendijk, David I. Vernon, Gerard C. van Rhoon, Kristian Boot
Publikováno v:
Photochemical & photobiological sciences, 3(3), 263-267. Royal Society of Chemistry
Photochemical & Photobiological Sciences, 263(7), 1-2. Royal Society of Chemistry
Photochemical & Photobiological Sciences, 263(7), 1-2. Royal Society of Chemistry
An approach to induce increased protoporphyrin IX (PpIX) production in aminolevulinic acid (ALA)-based photodynamic therapy (PDT) of skin lesions is to elevate the skin temperature during topical ALA application. Increased skin temperature may increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29cdb205f0b319350358a1ca107e7d9
https://doi.org/10.1039/b309284d
https://doi.org/10.1039/b309284d
Autor:
Johanna T. H. M. van den Akker, Henricus J. C. M. Sterenborg, Stanley B. Brown, David I. Vernon, J. Andrew Holroyd
Publikováno v:
Lasers in surgery and medicine, 34(2), 141-145. Wiley-Liss Inc.
Lasers in Surgery and Medicine, 34, 141-145. Wiley-Liss Inc.
Lasers in Surgery and Medicine, 34, 141-145. Wiley-Liss Inc.
Background and Objectives (Pre)cancerous skin lesions accumulate more protoporphyrin IX (PpIX) upon topical application of 5-aminolevulinic acid (ALA) than the surrounding normal skin. This might be the result of a higher percutaneous penetration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3be993d098c3aaba261b5aaaf343e6
https://doi.org/10.1002/lsm.20004
https://doi.org/10.1002/lsm.20004
Publikováno v:
British Journal of Cancer
m-Tetra(hydroxyphenyl)chlorin (m-THPC, Foscan, Temoporfin) has an unusually high photodynamic efficacy which cannot be explained by its photochemical properties alone. In vivo interactions are therefore of critical importance in determining this high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a50c575bac57e79cf672df37ee31aa0
http://europepmc.org/articles/PMC2394256
http://europepmc.org/articles/PMC2394256
Publikováno v:
Photochemistry and Photobiology. 69:482-488
Temoporfin (m-THPC) is an extremely powerful photosensitizing drug, more than 100-fold more photocytotoxic than Photofrin and many other drugs. The reasons for this are not yet known but are likely to be associated with the mechanism of uptake of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eb9d3104c1827d983d76774b41a7792
https://doi.org/10.1111/j.1751-1097.1999.tb03316.x
https://doi.org/10.1111/j.1751-1097.1999.tb03316.x
Publikováno v:
Langmuir. 24:9230-9232
We report a new supramolecular method for the synthesis of well-defined pristine C 60/polymer colloid nanocomposites in water. The colloids include polymer micelles and emulsion particles. To a polymer colloid solution in water or alcohol, we introdu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d49866cea1215f139f89274382b57e0
https://doi.org/10.1021/la801968x
https://doi.org/10.1021/la801968x