Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David Hill-Eubanks"'
Autor:
Viktoria Csato, Sharifah Z. S. A. Kadir, Kaivan Khavandi, Hayley Bennett, Sarah Sugden, Alison M. Gurney, Harry A. T. Pritchard, David Hill‐Eubanks, Philip Eaton, Mark T. Nelson, Adam S. Greenstein
Publikováno v:
Physiological Reports, Vol 7, Iss 22, Pp n/a-n/a (2019)
Abstract We investigated the biomechanical relationship between intraluminal pressure within small mesenteric resistance arteries, oxidant activation of PKG, Ca2+ sparks, and BK channel vasoregulation. Mesenteric resistance arteries from wild type (W
Externí odkaz:
https://doaj.org/article/8785c9dfa9f3404c9c302b284da289f5
Publikováno v:
eLife, Vol 7 (2018)
We recently reported that the inward-rectifier Kir2.1 channel in brain capillary endothelial cells (cECs) plays a major role in neurovascular coupling (NVC) by mediating a neuronal activity-dependent, propagating vasodilatory (hyperpolarizing) signal
Externí odkaz:
https://doaj.org/article/36a3959b2839416b96d944daee300602
Publikováno v:
The Journal of Physiology. 601:889-901
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0632a11b446270e4b7385017f5523003
https://doi.org/10.1113/jp282246
https://doi.org/10.1113/jp282246
Autor:
Nicholas R. Klug, Maria Sancho, Albert L. Gonzales, Thomas J. Heppner, Rochelle Irene C. O’Brien, David Hill-Eubanks, Mark T. Nelson
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Arteriolar smooth muscle cells (SMCs) and capillary pericytes dynamically regulate blood flow in the central nervous system in the face of fluctuating perfusion pressures. Pressure-induced depolarization and Ca 2+ elevation provide a mechanism for re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ae658ac3b0a418e887c9b4eac1c5012
https://doi.org/10.1073/pnas.2216421120
https://doi.org/10.1073/pnas.2216421120
Autor:
Maria Sancho, Nicholas R. Klug, Amreen Mughal, Masayo Koide, Saul Huerta de la Cruz, Thomas J. Heppner, Adrian D. Bonev, David Hill-Eubanks, Mark T. Nelson
Publikováno v:
Sci Signal
The dense network of capillaries composed of capillary endothelial cells (cECs) and pericytes lies in close proximity to all neurons, ideally positioning it to sense neuron- and glial-derived compounds that enhance regional and global cerebral perfus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3454ce1c75f0c8fb2383cf7f7d31555e
https://europepmc.org/articles/PMC9623876/
https://europepmc.org/articles/PMC9623876/
Publikováno v:
Proc Natl Acad Sci U S A
The phosphoinositide, phosphatidylinositol 4,5-bisphosphate (PIP(2)), has long been established as a major contributor to intracellular signaling, primarily by virtue of its role as a substrate for phospholipase C (PLC). Signaling by G(q)-protein–c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5b987d1ee54356bcfdf98d4e33c7eda
https://pubmed.ncbi.nlm.nih.gov/32764146
https://pubmed.ncbi.nlm.nih.gov/32764146
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(15)
Capillaries, the smallest blood vessels, mediate the on-demand delivery of oxygen and nutrients required to support the function of active cells throughout the brain. But how blood flow is directed to cells in active brain regions to satisfy their en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aef1d03a79b1120983f534be99306775
https://pubmed.ncbi.nlm.nih.gov/29581272
https://pubmed.ncbi.nlm.nih.gov/29581272
Autor:
Thomas A, Longden, Fabrice, Dabertrand, Masayo, Koide, Albert L, Gonzales, Nathan R, Tykocki, Joseph E, Brayden, David, Hill-Eubanks, Mark T, Nelson
Publikováno v:
Nature neuroscience. 20(5)
Blood flow into the brain is dynamically regulated to satisfy the changing metabolic requirements of neurons, but how this is accomplished has remained unclear. Here we demonstrate a central role for capillary endothelial cells in sensing neural acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c0054638a5d523664c091181c2aec4a
https://pubmed.ncbi.nlm.nih.gov/28440803
https://pubmed.ncbi.nlm.nih.gov/28440803