Zobrazeno 1 - 10
of 92
pro vyhledávání: '"David Hepworth"'
Autor:
Justin Hall, Amy Brault, Fabien Vincent, Shawn Weng, Hong Wang, Darren Dumlao, Ann Aulabaugh, Dikran Aivazian, Dana Castro, Ming Chen, Jeffrey Culp, Ken Dower, Joseph Gardner, Steven Hawrylik, Douglas Golenbock, David Hepworth, Mark Horn, Lyn Jones, Peter Jones, Eicke Latz, Jing Li, Lih-Ling Lin, Wen Lin, David Lin, Frank Lovering, Nootaree Niljanskul, Ryan Nistler, Betsy Pierce, Olga Plotnikova, Daniel Schmitt, Suman Shanker, James Smith, William Snyder, Timothy Subashi, John Trujillo, Edyta Tyminski, Guoxing Wang, Jimson Wong, Bruce Lefker, Leslie Dakin, Karen Leach
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184843 (2017)
Cyclic GMP-AMP synthase (cGAS) initiates the innate immune system in response to cytosolic dsDNA. After binding and activation from dsDNA, cGAS uses ATP and GTP to synthesize 2', 3' -cGAMP (cGAMP), a cyclic dinucleotide second messenger with mixed 2'
Externí odkaz:
https://doaj.org/article/6bb0be80b7c34a3aa6c36d9154eb7079
Autor:
Olga V. Sinitsyna, Valentine V. Makarov, Kara McGeachy, Tatyana Bukharova, Eric Whale, David Hepworth, Igor V. Yaminsky, Natalia O. Kalinina, Michael E. Taliansky, Andrew J. Love
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 8, p 1814 (2019)
We produced and isolated tobacco mosaic virus-like particles (TMV VLPs) from bacteria, which are devoid of infectious genomes, and found that they have a net negative charge and can bind calcium ions. Moreover, we showed that the TMV VLPs could assoc
Externí odkaz:
https://doaj.org/article/762c07f8ca9942d7b47abb7413a95963
Autor:
Jonathan David Hepworth
Publikováno v:
Mormon Studies Review. 9:166-170
Autor:
Olga V. Sinitsyna, Eric Whale, Igor V. Yaminsky, Andrew J. Love, Kara D. McGeachy, Natalia O. Kalinina, Michael Taliansky, David Hepworth
Publikováno v:
Cellulose. 27:2381-2387
Tobacco mosaic virus-like nanoparticles and nanocellulose are materials with great potential for use in bionanotechnology. We used atomic force microscopy to study the interaction between these materials at the nanoscale. It was found that they could
Autor:
Agustin Casimiro-Garcia, Christophe Allais, Agnes Brennan, Chulho Choi, Gabriela Dower, Kathleen A. Farley, Margaret Fleming, Andrew Flick, Richard K. Frisbie, Justin Hall, David Hepworth, Hannah Jones, John D. Knafels, Steve Kortum, Frank E. Lovering, John P. Mathias, Sashi Mohan, Paul M. Morgan, Chuenlei Parng, Kevin Parris, Nick Pullen, Franklin Schlerman, John Stansfield, Joseph W. Strohbach, Felix F. Vajdos, Fabien Vincent, Hong Wang, Xiaolun Wang, Robert Webster, Stephen W. Wright
Publikováno v:
Journal of medicinal chemistry. 65(1)
A diaryl ketone series was identified as vanin-1 inhibitors from a high-throughput screening campaign. While this novel scaffold provided valuable probe
Autor:
Patrick Robert Verhoest, David Hepworth, Tristan S. Maurer, Charlotte Moira Norfor Allerton, Martin Paul Edwards
Publikováno v:
Drug discovery today. 27(2)
Successful small-molecule drug design requires a molecular target with inherent therapeutic potential and a molecule with the right properties to unlock its potential. Present-day drug design strategies have evolved to leave little room for improveme
Autor:
David Hepworth
Der berühmteste Zebrastreifen der Welt … führt zu den Abbey Road Studios Das ikonenhafte Covermotiv der Beatles vom Abbey Road-Album löste einen unvergleichlichen Hype aus. Jeder Musikfan musste sich von nun an auf dem kleinen Straßenabschnitt
Autor:
David Hepworth
The incredible history of how Abbey Road became the most famous recording studio in the world.'There are certain things that are mythical. Abbey Road is mythical.'—Nile Rodgers Many people will recognize the famous crosswalk. Some visitors may ha
Autor:
Jeanne Chang, Ravi G. Kurumbail, Margaret Fleming, Joanne Brodfuehrer, Katherine L. Lee, Frank Lovering, Shashi Mohan, Heather V. Dowty, Fabien Vincent, Jayasankar Jasti, Steve Kortum, Christoph W. Zapf, Jotham Wadsworth Coe, Christophe Allais, Strohbach Joseph Walter, Nikolaos Papaioannou, Ann Aulabaugh, Julia A. Guzova, Paul Morgan, Richard K. Frisbie, WeiDong Ding, David Hepworth
Publikováno v:
European Journal of Medicinal Chemistry. 145:606-621
Many diseases are believed to be driven by pathological levels of reactive oxygen species (ROS) and oxidative stress has long been recognized as a driver for inflammatory disorders. Apoptosis signal-regulating kinase 1 (ASK1) has been reported to be
Autor:
Mohamed Saafi, Yin Chi, Bo Huang, Colin J. Lambert, Eric Whale, David Hepworth, Nigel J. Fullwood, Jianqiao Ye
Publikováno v:
Construction and Building Materials. 299:123867
Ordinary Portland cement (OPC) is the binding element in concrete materials and, CO2 emissions associated with its manufacturing and use is about 8% of the world's CO2 emissions. The engineering properties of hardened concrete depend on the amount of