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pro vyhledávání: '"David Heinkel"'
Publikováno v:
Osteoarthritis and Cartilage. 11(6):463-470
Objectives : Thyroid hormones induce features of the hypertrophic phenotype in mature articular chondrocytes as well as in growth plate chondrocytes. Hypertrophic chondrocytes are responsible for extracellular matrix mineralization, with formation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee1b8194c362d1b8d76bc8f05ac11c9
Autor:
David Heinkel, Kevin R. Seibenlist, Michael W. Mosesson, Claudia M. Gohr, Ann K. Rosenthal, Ikuko Masuda
Publikováno v:
Thrombosis and haemostasis. 91(3)
SummaryTransglutaminases are a family of enzymes that catalyze the formation of ɛ-(γ-glutamyl)lysine isopeptide bonds in proteins, an activity that has been implicated in the pathogenesis of cartilage matrix mineralization in degenerative arthritis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fae307db33cb7376cbd48a90d09247
https://pubmed.ncbi.nlm.nih.gov/14983233
https://pubmed.ncbi.nlm.nih.gov/14983233
Publikováno v:
Frontiers in Bioscience. 9:3257
Calcium pyrophosphate dihydrate (CPPD) crystals are common components of osteoarthritic joints and correlate with a poor prognosis. Transglutaminase (Tgase) enzymes have been implicated in pathologic mineralization in cartilage; yet, definitive studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee69d57b18132ff69510e9ba756b032
https://doi.org/10.2741/1477
https://doi.org/10.2741/1477