Zobrazeno 1 - 10
of 312
pro vyhledávání: '"David Hardy"'
Serotonin reuptake inhibitors improve muscle stem cell function and muscle regeneration in male mice
Autor:
Mylène Fefeu, Michael Blatzer, Anita Kneppers, David Briand, Pierre Rocheteau, Alexandre Haroche, David Hardy, Mélanie Juchet-Martin, Anne Danckaert, François Coudoré, Abdulkarim Tutakhail, Corinne Huchet, Aude Lafoux, Rémi Mounier, Olivier Mir, Raphaël Gaillard, Fabrice Chrétien
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Serotonin reuptake inhibitor antidepressants such as fluoxetine are widely used to treat mood disorders. The mechanisms of action include an increase in extracellular level of serotonin, neurogenesis, and growth of vessels in the brain. We i
Externí odkaz:
https://doaj.org/article/e38e2d2ee87c4271aef118d9c4f7a763
Autor:
Alexandra Maure, Emeline Lawarée, Francesco Fiorentino, Alexandre Pawlik, Saideep Gona, Alexandre Giraud-Gatineau, Matthew J G Eldridge, Anne Danckaert, David Hardy, Wafa Frigui, Camille Keck, Claude Gutierrez, Olivier Neyrolles, Nathalie Aulner, Antonello Mai, Mélanie Hamon, Luis B Barreiro, Priscille Brodin, Roland Brosch, Dante Rotili, Ludovic Tailleux
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002259 (2024)
Antituberculosis drugs, mostly developed over 60 years ago, combined with a poorly effective vaccine, have failed to eradicate tuberculosis. More worryingly, multiresistant strains of Mycobacterium tuberculosis (MTB) are constantly emerging. Innovati
Externí odkaz:
https://doaj.org/article/e2eedf80218b48f79d34efc207ddd2fb
Autor:
Nick Sevdalis, Mario Petrou, Katie Richards, Rashmi Kumar, Lucy Goulding, Kia-Chong Chua, Kathryn Watson, Joanna Burridge, DAVID HARDY, Sunil Bhudia, Manuela Russo, Rachel Rowan Olive, Barbora Krausova, Avlonitis Vassilios, Baig Kamran, Noorani Alia, Khan Habib
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Introduction Being on a waiting list for elective (planned) cardiac surgery can be physically and psychologically challenging for patients. Research suggests that stress associated with waiting for surgery is dependent on different individual and con
Externí odkaz:
https://doaj.org/article/a3a7b2633bd14e7aa1049ea67018cf7a
Publikováno v:
ACS Omega, Vol 8, Iss 45, Pp 42311-42318 (2023)
Externí odkaz:
https://doaj.org/article/c58340c982594b38b0e0b269e796eea0
Autor:
Alexis Lamiable, Tiphaine Champetier, Francesco Leonardi, Ethan Cohen, Peter Sommer, David Hardy, Nicolas Argy, Achille Massougbodji, Elaine Del Nery, Gilles Cottrell, Yong-Jun Kwon, Auguste Genovesio
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Biological sciences, drug discovery and medicine rely heavily on cell phenotype perturbation and microscope observation. However, most cellular phenotypic changes are subtle and thus hidden from us by natural cell variability: two cells in t
Externí odkaz:
https://doaj.org/article/998060b82d274222910792db9a50f65a
Autor:
Guilherme Dias de Melo, Victoire Perraud, Flavio Alvarez, Alba Vieites-Prado, Seonhee Kim, Lauriane Kergoat, Anthony Coleon, Bettina Salome Trüeb, Magali Tichit, Aurèle Piazza, Agnès Thierry, David Hardy, Nicolas Wolff, Sandie Munier, Romain Koszul, Etienne Simon-Lorière, Volker Thiel, Marc Lecuit, Pierre-Marie Lledo, Nicolas Renier, Florence Larrous, Hervé Bourhy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Anosmia was identified as a hallmark of COVID-19 early in the pandemic, however, with the emergence of variants of concern, the clinical profile induced by SARS-CoV-2 infection has changed, with anosmia being less frequent. Here, we assessed
Externí odkaz:
https://doaj.org/article/dc7c96ca45ad44e181d1a009fdd44754
Autor:
Laëtitia Douguet, Ingrid Fert, Jodie Lopez, Benjamin Vesin, Fabien Le Chevalier, Fanny Moncoq, Pierre Authié, Trang‐My Nguyen, Amandine Noirat, Fabien Névo, Catherine Blanc, Maryline Bourgine, David Hardy, François Anna, Laleh Majlessi, Pierre Charneau
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract Human papillomavirus (HPV) infections are the cause of all cervical and numerous oropharyngeal and anogenital cancers. The currently available HPV vaccines, which induce neutralizing antibodies, have no therapeutic effect on established tumo
Externí odkaz:
https://doaj.org/article/322a19d1d52f4623ae50d523d363e035
Autor:
Guilherme Dias de Melo, Victoire Perraud, Flavio Alvarez, Alba Vieites-Prado, Seonhee Kim, Lauriane Kergoat, Anthony Coleon, Bettina Salome Trüeb, Magali Tichit, Aurèle Piazza, Agnès Thierry, David Hardy, Nicolas Wolff, Sandie Munier, Romain Koszul, Etienne Simon-Lorière, Volker Thiel, Marc Lecuit, Pierre-Marie Lledo, Nicolas Renier, Florence Larrous, Hervé Bourhy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/4bea1d38cb7045f78395dc43c3604dea
Autor:
Phanramphoei N. Frantz, Aleksandr Barinov, Claude Ruffié, Chantal Combredet, Valérie Najburg, Guilherme Dias de Melo, Florence Larrous, Lauriane Kergoat, Samaporn Teeravechyan, Anan Jongkaewwattana, Emmanuelle Billon-Denis, Jean-Nicolas Tournier, Matthieu Prot, Laurine Levillayer, Laurine Conquet, Xavier Montagutelli, Magali Tichit, David Hardy, Priyanka Fernandes, Hélène Strick-Marchand, James Di Santo, Etienne Simon-Lorière, Hervé Bourhy, Frédéric Tangy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Here the authors generate a measles virus-based vaccine expressing SARSCoV-2 spike protein and show immunogenicity and protection in mice and hamsters, including neutralization of circulating variants of concerns in vitro.
Externí odkaz:
https://doaj.org/article/5eea106784d445baadd6d500eadbdebc
Autor:
Benoît Henry, Geoffroy Volle, Hilaire Akpovi, Laure Gineau, Camille Roussel, Papa Alioune Ndour, Félicien Tossou, Felipe Suarez, Friso Palstra, Aurélie Fricot, Charlotte Chambrion, Julien Solinc, Julie Nguyen, Mathilde Garé, Florentin Aussenac, Charles-Henry Cottart, Christine Keyser, Rafiou Adamou, Magali Tichit, David Hardy, Nadine Fievet, Jérôme Clain, André Garcia, David Courtin, Olivier Hermine, Audrey Sabbagh, Pierre Buffet
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104167- (2022)
Summary: Background: In malaria-endemic areas, subjects from specific groups like Fulani have a peculiar protection against malaria, with high levels of IgM but also frequent anaemia and splenomegaly. The mechanisms underlying this phenotype remain e
Externí odkaz:
https://doaj.org/article/44ce45a575c74486830d8723e954cac6