Zobrazeno 1 - 10
of 58
pro vyhledávání: '"David H. Root"'
Autor:
Jayson B. Ball, Connor J. McNulty, Suzanne M. Green-Fulgham, Joseph M. Dragavon, Igor R. Correia Rocha, Maggie R. Finch, Emily D. Prévost, Imaad I. Siddique, Brodie J. Woodall, Linda R. Watkins, Michael V. Baratta, David H. Root
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
A challenge for central nervous system (CNS) tissue analysis in neuroscience research has been the difficulty to codetect and colocalize gene and protein expression in the same tissue. Given the importance of identifying gene expression relative to p
Externí odkaz:
https://doaj.org/article/853326147cf740d7bc6e261533903e46
Publikováno v:
iScience, Vol 2, Iss , Pp 51-62 (2018)
Summary: Ventral tegmental area (VTA) neurons play roles in reward and aversion. The VTA has, in addition to dopamine neurons, glutamatergic neurons expressing VGluT2. Here, by determining the firing patterns of VTA-VGluT2 neurons expressing channelr
Externí odkaz:
https://doaj.org/article/fa821e8806cf4d9e86bf3ed3e81891ef
Autor:
David J. Barker, Jorge Miranda-Barrientos, Shiliang Zhang, David H. Root, Hui-Ling Wang, Bing Liu, Erin S. Calipari, Marisela Morales
Publikováno v:
Cell Reports, Vol 21, Iss 7, Pp 1757-1769 (2017)
Summary: The lateral habenula (LHb) is a brain structure that participates in cognitive and emotional processing and has been implicated in several mental disorders. Although one of the largest inputs to the LHb originates in the lateral preoptic are
Externí odkaz:
https://doaj.org/article/23e296b0772e4a4992657edd16043089
Autor:
Connor J. McNulty, Isabella P. Fallon, Jose Amat, Rory J. Sanchez, Nathan R. Leslie, David H. Root, Steven F. Maier, Michael V. Baratta
Publikováno v:
Neuropsychopharmacology. 48:498-507
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7bebf753a4c137d6612b353a9e500b5
https://doi.org/10.1038/s41386-022-01443-w
https://doi.org/10.1038/s41386-022-01443-w
Autor:
Emily D. Prévost, Alysabeth Phillips, Kristoffer Lauridsen, Gunnar Enserro, Bodhi Rubinstein, Daniel Alas, Dillon J. McGovern, Annie Ly, Makaila Banks, Connor McNulty, Yoon Seok Kim, Lief E. Fenno, Charu Ramakrishnan, Karl Deisseroth, David H. Root
A unique population of ventral tegmental area (VTA) neurons co-transmits glutamate and GABA as well as functionally signals rewarding and aversive outcomes. However, the circuit inputs to VTA VGluT2+VGaT+ neurons are unknown, limiting our understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb794d20eeed59b8fca71e7e271e49d
https://doi.org/10.1101/2023.04.06.535959
https://doi.org/10.1101/2023.04.06.535959
Autor:
Dillon J. McGovern, Abigail M. Polter, Annie Ly, Emily D. Prevost, Connor McNulty, David H. Root
A two-neuron model of ventral tegmental area (VTA) opioid function classically involves VTA GABA neuron regulation of VTA dopamine neurons via a mu-opioid receptor dependent inhibitory circuit. However, this model predates the discovery of a third ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a89d3224dabcbfde9814721d27ad8098
https://doi.org/10.1101/2022.12.11.519972
https://doi.org/10.1101/2022.12.11.519972
Autor:
Dillon J. McGovern, Annie Ly, Koy L. Ecton, David T. Huynh, Emily D. Prévost, Shamira C. Gonzalez, Connor J. McNulty, Andrew R. Rau, Shane T. Hentges, Tanya L. Daigle, Bosiljka Tasic, Michael V. Baratta, David H. Root
Publikováno v:
Molecular Psychiatry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64d6e47c6cf5934a40c420579ccce94a
https://doi.org/10.1038/s41380-022-01858-3
https://doi.org/10.1038/s41380-022-01858-3
Publikováno v:
J Neurosci
Ventral tegmental area (VTA) glutamate neurons signal and participate in reward and aversion-based behaviors. However, the neurochemical mechanisms that underlie how these neurons contribute to motivated behaviors is unknown. We used a combination of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43aa7c35cb618b2912ba15deb1037f1f
https://doi.org/10.1523/jneurosci.1419-20.2021
https://doi.org/10.1523/jneurosci.1419-20.2021
Autor:
Annie, Ly, David H, Root
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 47(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::658152be9a18762a6978660c0627fc48
https://pubmed.ncbi.nlm.nih.gov/34916591
https://pubmed.ncbi.nlm.nih.gov/34916591
Ventral tegmental area glutamate neurons mediate the nonassociative consequences of traumatic stress
Autor:
Ly A, David H. Root, Ecton Kl, Andrew R. Rau, David T. Huynh, Shane T. Hentges, Baratta Mv, Dillon J. McGovern
SUMMARYExposure to trauma is a risk factor for the development of a number of mood disorders, and may enhance vulnerability to future adverse life events. Recent data implicate ventral tegmental area (VTA) glutamate neuronal activity as functionally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b3303cced2e2287a998984a17534904
https://doi.org/10.1101/2021.04.02.438264
https://doi.org/10.1101/2021.04.02.438264