Zobrazeno 1 - 10
of 52
pro vyhledávání: '"David H. Peck"'
Publikováno v:
Biomarker Insights, Vol 2, Pp 377-384 (2007)
Introduction: The development of peritoneal metastases is a significant clinical issue in the treatment of abdominal cancers and is associated with poor prognosis. We have previously shown that ICAM-1-CD43 interaction plays a significant role in tumo
Externí odkaz:
https://doaj.org/article/ff39d3796a904192815c7310cba31a1c
Autor:
Paul Ziprin, Charles Bailey, David H. Peck, Rupert Negus, Robert D. Goldin, Alistair Morris, Ara Darzi, Paola Allavena
Publikováno v:
Clinical & Experimental Metastasis. 24:121-130
Chemokines promote tumour progression by enhancing proliferation and modifying the immune response. The purpose of this study was to test the hypothesis that CCL2 monocyte chemotactic protein-1 (MCP-1) contributes to the progression of colorectal can
Publikováno v:
Surgical Endoscopy. 19:747-750
Concern has long existed regarding the possible iatrogenic spread of variant Creutzfeldt-Jakob disease (v-CJD) through surgery. This had been fueled by recent reports of bovine spongiform encephalopathy in U.S. cattle and the first probable case of b
Autor:
Paul F. Ridgway, Ara Darzi, Nawar A. Alkhamesi, David H. Peck, Paul Ziprin, Paraskevas Paraskeva
Publikováno v:
Journal of Surgical Research. 124:180-186
Hypoxia within solid adenocarcinomas and protease up-regulation has been independently implicated as poor prognostic indicators in a variety of tumor types. The authors hypothesize that Matrix Metalloproteases (MMP) are up-regulated in direct respons
Publikováno v:
Wound Repair and Regeneration. 13:158-164
Reepithelialization is an essential step in successful cutaneous wound healing. Human keratinocytes, integral in this process, have been shown to have increased motility in the hypoxic healing edge of wounds correlating with the clinical success of s
Autor:
L. Harbin, P.B. Rajan, Paul Ziprin, David H. Peck, Paul F. Ridgway, Rosamond Jacklin, Ara Darzi
Publikováno v:
Journal of Surgical Research. 122:83-88
The recurring theme in cystosarcoma phyllodes (CSP) is one of underdiagnosis by pathologists and undertreatment by surgeons. Major areas of investigation relating to the diagnosis of CSP center on accurate preoperative diagnosis, elucidating the rele
Autor:
Robert D. Goldin, Colin Bicknell, Nawar A. Alkhamesi, Nicholas J.W. Cheshire, John H.N. Wolfe, Rodney A. Foale, Ara Darzi, M.W. Clark, Michael Jenkins, David H. Peck, Mark G. Cowling
Publikováno v:
Journal of Endovascular Therapy. 11:483-493
PURPOSE To investigate if relationships exist among macrophage infiltration, plasma matrix metalloproteinase (MMP) levels, and the number of emboli generated during endoluminal carotid interventions. METHODS Carotid endarterectomy specimens excised a
Publikováno v:
Cell Communication & Adhesion. 10:141-154
Peritoneal metastases frequently occur in different gastrointestinal cancers and have a poor prognosis. It is known that surgical injury promotes tumor growth and local recurrence rates and also the degree of surgical trauma correlated with the amoun
Autor:
Clare M. Isacke, David H. Peck
Publikováno v:
Journal of Cell Science. 111:1595-1601
CD44 is the principle transmembrane receptor for the extracellular matrix glycosaminoglycan hyaluronan. This receptor:ligand interaction plays an essential role in a number of physiological events including tumour progression, lymphocyte homing into
Autor:
David H. Peck, Clare M. Isacke
Publikováno v:
Current Biology. 6(7):884-890
Background: CD44 is a transmembrane receptor for the extracellular matrix glycosaminoglycan, hyaluronan. This receptor–ligand interaction plays an essential role in tumour progression, in embryonic tissue morphogenesis and in leukocyte migration du