Liquid Biopsy for Proliferative Diabetic Retinopathy: Single-Cell Transcriptomics of Human Vitreous Reveals Inflammatory T-Cell Signature

Autor: Rachana Haliyur, MD, PhD, David H. Parkinson, MS, Feiyang Ma, PhD, Jing Xu, PhD, Qiang Li, MD, PhD, Yuanhao Huang, Lam C. Tsoi, PhD, Rachael Bogle, MS, Jie Liu, PhD, Johann E. Gudjonsson, MD, Rajesh C. Rao, MD

Publikováno v: Ophthalmology Science, Vol 4, Iss 6, Pp 100539- (2024)

Purpose: Current therapies for proliferative diabetic retinopathy (PDR) do not specifically target VEGF-independent, cell-type–specific processes that lead to vision loss, such as inflammatory pathways. This study aimed to identify targetable cell

Externí odkaz: https://doaj.org/article/f4ad998418104f48bf24a27ebc226ad3

Contributors

Autor: Richard L Abbott, Sean D Adrean, Abdulrahman Al-Muammar, Jihan Akhtar, Eduardo C Alfonso, Richard C Allen, M Camille Almond, Lênio Alvarenga, Wallace LM Alward, Renato Ambrósio, Mohammad Anwar, Dimitri T Azar, James L Ball, Neal P Barney, Rebecca M Bartow, Jules Baum, Michael W Belin, Jason H Bell, Beth Ann Benetz, Zachary Berbos, Roger W Beuerman, Arpita Kadakia Bhasin, Pooja V Bhat, Joseph M Biber, Maria Bidros, Andrea D Birnbaum, Charles S Bouchard, Jay C Bradley, James D Brandt, Richard D Brasington, Harilaos S Brilakis, Cat N Burkat, Marta Calatayud, J Douglas Cameron, Mauro Campos, Emmett F Carpel, H Dwight Cavanagh, Cordelia Chan, Richard I Chang, Bernard H Chang, Kenneth C Chern, Steven Ching, James Chodosh, Phillip H Choo, Gary Chung, Joseph B Ciolino, Janine A Clayton, Elisabeth J Cohen, Oliver Comyn, M Soledad Cortina, John W Cowden, Christopher R Croasdale, Richard S Davidson, Elizabeth A Davis, Sheraz M Daya, Denise de Freitas, David L DeMill, Lauro Augusto de Oliveira, Marc D de Smet, Luciene B de Sousa, Ali R Djalilian, Claes H Dohlman, Eric D Donnenfeld, Richard K Dortzbach, William T Driebe, Steven P Dunn, Ralph C Eagle, Sean L Edelstein, Richard A Eiferman, Joseph A Eliason, Marjan Farid, William J Faulkner, Robert S Feder, Vahid Feiz, Matthew T Feng, John H Fingert, George J Florakis, Luigi Fontana, Richard K Forster, C Stephen Foster, F Stuart Foster, Gary N Foulks, Mitchell H Friedlander, Masahiko Fukuda, Anat Galor, Theresa J Gan, Prashant Garg, Sumit Garg, David B Glasser, Kenneth M Goins, Debra A Goldstein, Chloe Gottlieb, Michael R Grimmett, Oscar Gris, Erich B Groos, William D Gruzensky, Jose L Güell, Preeya K Gupta, M Bowes Hamill, Kristin M Hammersmith, Pedram Hamrah, Sadeer B Hannush, David R Hardten, Andrew Harrison, Ellen L Heck, David G Heidemann, David C Herman, J Martin Heur, William G Hodge, Carol J Hoffman, Edward J Holland, Gary N Holland, Marc A Honig, Christopher T Hood, Eliza N Hoskins, Andrew J W Huang, David Huang, Jennifer I Hui, Joseph D Iuorno, W Bruce Jackson, Frederick A Jakobiec, Bennie H Jeng, James V Jester, David R Jordan, Terry L Kaiura, Carol L Karp, Douglas G Katz, Stephen C Kaufman, Robert C Kersten, Stephen S Khachikian, Jennifer H Kim, Joung Y Kim, Stella K Kim, Terry Kim, Colin M Kirkness, Stephen D Klyce, Douglas D Koch, Regis P Kowalski, Jay H Krachmer, Peter R Laibson, Stephen S Lane, Jonathan H Lass, W Barry Lee, Olivia A Lee, Michael A Lemp, Phoebe D Lenhart, Yan Li, Thomas J Liesegang, Michele C Lim, Lily Koo Lin, Michael P Lin, Thomas D Lindquist, Richard L Lindstrom, David Litoff, Christopher Liu, Careen Y Lowder, Anthony J Lubniewski, Hall T McGee, Ian W McLean, Marian S Macsai, Felicidad Manero, Mark J Mannis, Dimosthenis Mantopoulos, Carlos E Martinez, Csaba L Mártonyi, Raneen S Mashor, William D Mathers, Manisha N Mehta, David M Meisler, Shahzad I Mian, Darlene Miller, Corey A Miller, Monty Montoya, Merce Morral, Andrew L Moyes, Michael L Murphy, Nariman Nassiri, Kristiana D Neff, J Daniel Nelson, Jeffrey A Nerad, Marcelo V Netto, Christopher J Newton, Lisa M Nijm, Teruo Nishida, Bruce A Noble, Michael L Nordlund, Robert B Nussenblatt, David G O'Day, Jenny V Ongkosuwito, Karen W Oxford, David A Palay, Florentino E Palmon, Deval R Paranjpe, Mansi Parikh, David H Park, D J John Park, Matthew R Parsons, Charles J Pavlin, Eric S Pearlstein, Alicia Perry, W Matthew Petroll, Daryl R Pfister, Roswell R Pfister, Stephen C Pflugfelder, Francis W Price, Marianne O Price, Louis E Probst, John J Purcell, Andrew A E Pyott, Michael B Raizman, Leela V Raju, J Bradley Randleman, Gullapalli N Rao, Christopher J Rapuano, Charles D Reilly, Adimara de Candelaria Renesto, Renata A Rezende, Danielle M Robertson, David S Rootman, Jason S Rothman, Roy Scott Rubinfeld, Alan E Sadowsky, Shizuya Saika, Monali V Sakhalkar, James J Salz, Virender S Sangwan, Marinho Scarpi, Bradley H Scharf, Greg Schmidt, Artur Schmitt, Fernanda Piccoli Schmitt, Miriam T Schteingart, Ivan R Schwab, Brian L Schwam, Gary S Schwartz, H Nida Sen, Michael B Shapiro, Shigeto Shimmura, Neera Singal, Heather M Skeens, Craig A Skolnick, Allan R Slomovic, Janine A Smith, Michael E Snyder, Renée Solomon, Sarkis H Soukiasian, Sathish Srinivasan, John F Stamler, Roger F Steinert, Glenn L Stoller, Barbara W Streeten, R Doyle Stulting, Alan Sugar, Joel Sugar, Donald Tan, Joseph Tauber, Mark A Terry, Howard H Tessler, Marta Torrabadella, Elias I Traboulsi, William B Trattler, Julie H Tsai, David T Tse, Elmer Y Tu, Roxana Ursea, Pravin K Vaddavalli, Woodford S Van Meter, Gary A Varley, Roshni Vasaiwala, Anthony J Verachtert, David D Verdier, Ana Carolina Vieira, Vanee V Virasch, Li Wang, George O Waring, Michael A Warner, Kevin J Warrian, Guy F Webster, Mitchell P Weikert, Robert W Weisenthal, Jayne S Weiss, Pongmas Wichiensin, Kirk R Wilhelmus, Steven E Wilson, Maria A Woodward, Richard W Yee, Sonya Yoo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4b98029da83cc92c271fdbbe3702508
https://doi.org/10.1016/b978-0-323-06387-6.00005-2

Traumatic flap displacement and subsequent diffuse lamellar keratitis after laser in situ keratomileusis

Autor: David H. Park, Susan Schloff, Gary S. Schwartz, Stephen S. Lane

Publikováno v: Journal of cataract and refractive surgery. 27(5)

A 45-year-old man was struck in the left eye by the edge of a paper shopping bag 3 weeks after having laser in situ keratomileusis (LASIK). The injury resulted in partial displacement of the LASIK flap. The patient developed diffuse lamellar keratiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e50e98501b4712248e144c4a5743f22
https://pubmed.ncbi.nlm.nih.gov/11377912