Zobrazeno 1 - 10
of 78
pro vyhledávání: '"David H. Bechhofer"'
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT The Bacillus subtilis genome encodes four 3′ exoribonucleases: polynucleotide phosphorylase (PNPase), RNase R, RNase PH, and YhaM. Previous work showed that PNPase, encoded by the pnpA gene, is the major 3′ exonuclease involved in mRNA t
Externí odkaz:
https://doaj.org/article/4bfff2e6f17e44d68c5b4ed1d6b35d57
Publikováno v:
RNA Biology. 18:1692-1701
Polynucleotide phosphorylase (PNPase), a 3' exoribonuclease that degrades RNA in the 3'-to-5' direction, is the major mRNA decay activity in Bacillus subtilis. PNPase is known to be inhibited in vitro by strong RNA secondary structure, and rapid mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::411a2f19fedff2dc023de8fed42f74a0
https://doi.org/10.1080/15476286.2020.1864183
https://doi.org/10.1080/15476286.2020.1864183
Autor:
Shakti, Ingle, Shivani, Chhabra, Jiandong, Chen, Michael B, Lazarus, Xing, Luo, David H, Bechhofer
Publikováno v:
RNA (New York, N.Y.). 28(2)
The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7eaec0f4792e4790d959f9b2d623e349
https://pubmed.ncbi.nlm.nih.gov/34815358
https://pubmed.ncbi.nlm.nih.gov/34815358
Autor:
Shakti, Ingle, Shivani, Chhabra, Denise, Laspina, Elizabeth, Salvo, Bo, Liu, David H, Bechhofer
Publikováno v:
RNA Biol
Polynucleotide phosphorylase (PNPase), a 3ʹ exoribonuclease that degrades RNA in the 3ʹ-to-5ʹ direction, is the major mRNA decay activity in Bacillus subtilis. PNPase is known to be inhibited in vitro by strong RNA secondary structure, and rapid m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c117ab2a7e5df3fb7e873738004b20b1
https://pubmed.ncbi.nlm.nih.gov/33323028
https://pubmed.ncbi.nlm.nih.gov/33323028
Publikováno v:
Critical reviews in biochemistry and molecular biology. 54(3)
Ribonucleases (RNases) are mediators in most reactions of RNA metabolism. In recent years, there has been a surge of new information about RNases and the roles they play in cell physiology. In this review, a detailed description of bacterial RNases i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76f25c19d15351a59903389723e4acb
https://pubmed.ncbi.nlm.nih.gov/31464530
https://pubmed.ncbi.nlm.nih.gov/31464530
Publikováno v:
Nucleic Acids Research
The recent findings that the narrow-specificity endoribonuclease RNase III and the 5′ exonuclease RNase J1 are not essential in the Gram-positive model organism, Bacillus subtilis, facilitated a global analysis of internal 5′ ends that are genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b277762102dcc9d2845b6d8104283205
http://europepmc.org/articles/PMC4838370
http://europepmc.org/articles/PMC4838370
Publikováno v:
Nucleic Acids Research
Timely turnover of RNA is an important element in the control of bacterial gene expression, but relatively few specific targets of RNA turnover regulation are known. Deletion of the Bacillus subtilis pnpA gene, encoding the major 3′ exonuclease tur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ccaf02c057ab1eacb4aac0a486aa9e
http://europepmc.org/articles/PMC4838369
http://europepmc.org/articles/PMC4838369
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c147a1528d2a13927845eb9f7e9319f3
https://doi.org/10.1096/fasebj.2020.34.s1.01988
https://doi.org/10.1096/fasebj.2020.34.s1.01988
Publikováno v:
Molecular Microbiology. 95:270-282
Stable RNA maturation is a key process in the generation of functional RNAs, and failure to correctly process these RNAs can lead to their elimination through quality control mechanisms. Studies of the maturation pathways of ribosomal RNA and transfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee544b739f582b2ccb8702ed24d9dc54
https://doi.org/10.1111/mmi.12863
https://doi.org/10.1111/mmi.12863
Publikováno v:
Molecular Microbiology. 94:41-55
Messenger RNA decay in Bacillus subtilis is accomplished by a combination of exoribonucleases and endoribonucleases. Intermediates in the decay process have not been readily detectable, and previous studies on mRNA decay have used a handful of highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91072a2ee6790f61ad9ba19e75578251
https://doi.org/10.1111/mmi.12748
https://doi.org/10.1111/mmi.12748