Zobrazeno 1 - 10
of 1 603
pro vyhledávání: '"David H. Adams"'
Autor:
Dimosthenis Pandis, MD, MSc, Navindra David, BS, Ahmed EI-Eshmawi, MD, Marc A. Miller, MD, Percy Boateng, MD, Ana Claudia Costa, MD, PhD, Philip Robson, PhD, Maria Giovanna Trivieri, MD, Zahi Fayad, PhD, Anelechi C. Anyanwu, MD, MSc, David H. Adams, MD
Publikováno v:
JTCVS Open, Vol 19, Iss , Pp 94-113 (2024)
Objective: The effect of mitral valve (MV) surgery on the natural history of ventricular arrhythmia (VA) in patients with arrhythmic MV prolapse remains unknown. We sought to evaluate the cumulative incidence of VA at 1 year after surgical mitral rep
Externí odkaz:
https://doaj.org/article/6e09588a8f2245a2814c5446524c6321
Autor:
Gideon M. Hirschfield, Katherine Arndtz, Amanda Kirkham, Yung-Yi Chen, Richard Fox, Anna Rowe, Jessica Douglas-Pugh, Douglas Thorburn, Eleanor Barnes, Guruprasad P. Aithal, Diana Hull, Khushpreet Bhandal, Kathryn Olsen, Paul Woodward, Siân Lax, Philip Newsome, David J. Smith, Antero Kallio, David H. Adams, Victoria Homer, Chris J. Weston
Publikováno v:
Hepatology Communications, Vol 8, Iss 5 (2024)
Background:. Primary sclerosing cholangitis is a progressive inflammatory liver disease characterized by biliary and liver fibrosis. Vascular adhesion protein-1 (VAP-1) is important in the inflammatory process driving liver fibrosis. We evaluated the
Externí odkaz:
https://doaj.org/article/1b222fe6ac3c4e409c92ca04f98f474a
Autor:
Aaron J. Weiss, MD, PhD, Arjun S. Yadaw, PhD, David L. Meretzky, MA, Matthew A. Levin, MD, David H. Adams, MD, Ken McCardle, MS, Gaurav Pandey, PhD, Ravi Iyengar, PhD
Publikováno v:
JTCVS Open, Vol 14, Iss , Pp 214-251 (2023)
Background: The Society of Thoracic Surgeons risk scores are widely used to assess risk of morbidity and mortality in specific cardiac surgeries but may not perform optimally in all patients. In a cohort of patients undergoing cardiac surgery, we dev
Externí odkaz:
https://doaj.org/article/10c37875637647a0b731be8f1022516d
Autor:
Alex L. Wilkinson, Samuel Hulme, James I. Kennedy, Emily R. Mann, Paul Horn, Emma L. Shepherd, Kelvin Yin, Marco Y.W. Zaki, Gareth Hardisty, Wei-Yu Lu, Pia Rantakari, David H. Adams, Marko Salmi, Matthew Hoare, Daniel A. Patten, Shishir Shetty
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107966- (2023)
Summary: Liver sinusoidal endothelial cells (LSEC) undergo significant phenotypic change in chronic liver disease (CLD), and yet the factors that drive this process and the impact on their function as a vascular barrier and gatekeeper for immune cell
Externí odkaz:
https://doaj.org/article/58c0bb4699c74d3e8cde69d28ccda647
Autor:
Kathryn Olsen, James Hodson, Vincenzo Ronca, Amber G. Bozward, Jennifer Hayden, Grace Wootton, Matthew Armstrong, David H. Adams, Omar El‐Sherif, James Ferguson, Ellen Knox, Tracey Johnston, Fiona Thompson, Ye Htun Oo
Publikováno v:
Hepatology Communications, Vol 5, Iss 7, Pp 1252-1264 (2021)
Autoimmune hepatitis (AIH) is an immune‐mediated chronic liver disease that affects all ages, including women of childbearing age. Optimal management during pregnancy is poorly defined. We aimed to explore the clinical and biochemical course of AIH
Externí odkaz:
https://doaj.org/article/f08765a8d480426d83d9baa2dbcebdaa
Autor:
Hynek Mergental, Richard W. Laing, Amanda J. Kirkham, M. Thamara P. R. Perera, Yuri L. Boteon, Joseph Attard, Darren Barton, Stuart Curbishley, Manpreet Wilkhu, Desley A. H. Neil, Stefan G. Hübscher, Paolo Muiesan, John R. Isaac, Keith J. Roberts, Manuel Abradelo, Andrea Schlegel, James Ferguson, Hentie Cilliers, Julian Bion, David H. Adams, Chris Morris, Peter J. Friend, Christina Yap, Simon C. Afford, Darius F. Mirza
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The shortage of viable donated livers limits patient access to liver transplantation. Here the authors report the use of normothermic machine perfusion to help identify viable organs from livers discarded based on current clinical criteria, which are
Externí odkaz:
https://doaj.org/article/c280eba6b1264d549b001554a3c7ab18
Autor:
Abhishek Chauhan, Lozan Sheriff, Mohammed T. Hussain, Gwilym J. Webb, Daniel A. Patten, Emma L. Shepherd, Robert Shaw, Christopher J. Weston, Debashis Haldar, Samuel Bourke, Rajan Bhandari, Stephanie Watson, David H. Adams, Steve P. Watson, Patricia F. Lalor
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The molecular mechanisms that drive irreversible acute liver failure remain poorly characterized. Here, the authors show that the recently discovered platelet receptor CLEC-2 (C-type lectin-like receptor) perpetuates and worsens liver damage during a
Externí odkaz:
https://doaj.org/article/a6f8dbdcb34b42c0a82ada447cf8eac9
Publikováno v:
JACC: Case Reports, Vol 1, Iss 4, Pp 495-499 (2019)
Mitral annular calcification tends to be significant in patients of advanced age or with underlying processes such as increased mechanical stress. When severe, it can significantly affect perioperative outcomes, especially if mitral decalcification i
Externí odkaz:
https://doaj.org/article/c1ea5c13635847ddaf5ae0d919d4c450
Autor:
Nwe Ni Than, James Hodson, Daniel Schmidt-Martin, Richard Taubert, Rebecca E. Wawman, Meemee Botter, Nishant Gautam, Kilian Bock, Rebecca Jones, Gautham D Appanna, Andrew Godkin, Aldo J. Montano-Loza, Frank Lammert, Christoph Schramm, Michael P. Manns, Mark Swain, Kelly W. Burak, David H. Adams, Gideon M Hirschfield, Ye Htun Oo
Publikováno v:
JHEP Reports, Vol 1, Iss 6, Pp 437-445 (2019)
Background & Aims: Treatment options remain limited for patients with autoimmune hepatitis (AIH), while there are still concerns over the consequences of long-term corticosteroid use. A few studies have suggested a role for B cell-driven autoimmune l
Externí odkaz:
https://doaj.org/article/bcb9f7c48c3a4df4a706283363e04ef1
Autor:
Yung-Yi Chen, Kathryn Arndtz, Gwilym Webb, Margaret Corrigan, Sarah Akiror, Evaggelia Liaskou, Paul Woodward, David H. Adams, Chris J. Weston, Gideon M. Hirschfield
Publikováno v:
JHEP Reports, Vol 1, Iss 5, Pp 369-376 (2019)
Background & Aims: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive inflammatory and fibrotic injury to the biliary tree. We sought to further delineate the contribution of macrophage lineages i
Externí odkaz:
https://doaj.org/article/f2463d17726849958175a35e455840f2