Zobrazeno 1 - 10
of 959
pro vyhledávání: '"David H Sachs"'
Autor:
Nalu Navarro-Alvarez, Zurab Machaidze, Christian Schuetz, Alexander Zhu, Wei-Hui Liu, Jigesh A Shah, Parsia A Vagefi, Nahel Elias, Leo Buhler, David H Sachs, James F Markmann, Heidi Yeh
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207272 (2018)
The liver's regenerative capacity is unique, but too small a segment can overwhelm its ability to simultaneously regenerate and support the host, resulting in liver dysfunction and death. Here we tested a temporary Xenogeneic Heterotopic Auxiliary Li
Externí odkaz:
https://doaj.org/article/349929d6cc4145d2887c5aba56ebd041
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Focusing on complex extremity trauma and volumetric muscle loss (VML) injuries, this review highlights: 1) the current pathophysiologic limitations of the injury sequela; 2) the gene editing strategy of the pig as a model that provides a novel treatm
Externí odkaz:
https://doaj.org/article/8c9f8b99cee8408497446cba5c557eca
Autor:
Christian Binder, Filip Cvetkovski, Felix Sellberg, Stefan Berg, Horacio Paternina Visbal, David H. Sachs, Erik Berglund, David Berglund
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The glycoprotein CD2 is a costimulatory receptor expressed mainly on T and NK cells that binds to LFA3, a cell surface protein expressed on e.g., antigen-presenting cells. CD2 has an important role in the formation and organization of the immunologic
Externí odkaz:
https://doaj.org/article/f7b94ce0ad6b470fa0ea4e7a4ec1e524
Publikováno v:
Journal of Molecular and Cellular Cardiology. 172:109-119
End stage heart failure is a terminal disease, and the only curative therapy is orthotopic heart transplantation. Due to limited organ availability, alternative strategies have received intense interest for treatment of patients with advanced heart f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1f3b9145c90c4f4ee2a8ce93a6322f
https://doi.org/10.1016/j.yjmcc.2022.07.013
https://doi.org/10.1016/j.yjmcc.2022.07.013
Publikováno v:
Transplantation. 106:928-937
Over the last 40 y, a specialized herd of miniature swine has been intentionally bred to develop lines of animals homozygous for the swine major histocompatibility complex (MHC), which have facilitated transplantation studies across reproducible MHC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3596fe15153bdaaa300a9442061da1
https://doi.org/10.1097/tp.0000000000003977
https://doi.org/10.1097/tp.0000000000003977
Publikováno v:
XenotransplantationREFERENCES.
Cardiovascular disease is common and has a high mortality. Due to the limited number of organs available for orthotopic heart transplantation, alternative therapies have received intense interest. In this commentary we contrast xenotransplantation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5352c833e04ad08dc0c727e6235895f7
https://pubmed.ncbi.nlm.nih.gov/36367201
https://pubmed.ncbi.nlm.nih.gov/36367201
Autor:
Megan Sykes, David H. Sachs
Publikováno v:
Nat Rev Nephrol
A major limitation of organ allotransplantation is the insufficient supply of donor organs. Consequently, thousands of patients die every year while waiting for a transplant. Progress in xenotransplantation that has permitted pig organ graft survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0b65a17708ea7259f6f79dcb7c9c89
https://pubmed.ncbi.nlm.nih.gov/36198911
https://pubmed.ncbi.nlm.nih.gov/36198911
Autor:
Thomas R, Spitzer, David H, Sachs
Publikováno v:
New England Journal of Medicine. 386:2332-2333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f05ee9320582e5218fde25ac00fb066
https://doi.org/10.1056/nejme2204651
https://doi.org/10.1056/nejme2204651
Autor:
Erin M Duggan, Hiroshi Sakai, Benjamin Piegari, Sarah Merl, Nathaly P Llore, Jeffrey Stern, Karina Bruestle, Dominik Hajosi, Dilrukshi K Ekanayake-Alper, David H Sachs, Megan Sykes, Robert J Hawley, Adam D Griesemer
Publikováno v:
Transplantation. 106:S285-S285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5281c93c32f07ae3cb66d6fe2acdf059
https://doi.org/10.1097/01.tp.0000886900.57458.eb
https://doi.org/10.1097/01.tp.0000886900.57458.eb
Autor:
Gabriel Cara-Fuentes, Dilrukshi K. Ekanayake‐Alper, Hironosuke Watanabe, David H. Sachs, Lennan Boyd, Gabriela E. Garcia, Kazuhiro Takeuchi, Megan Sykes, Thomas Pomposelli, Yuichiro Okumura, Kazuhiko Yamada, Dasari Amarnath, Akira Shimizu, Richard J. Johnson, Yuichi Ariyoshi
Publikováno v:
Xenotransplantation
Background Nephrotic syndrome is a common complication of pig-to-baboon kidney xenotransplantation (KXTx) that adversely affects outcomes. We have reported that upregulation of CD80 and down-regulation of SMPDL-3b in glomeruli have an important role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1091df2f327cf4574f62116796660170
https://europepmc.org/articles/PMC8957703/
https://europepmc.org/articles/PMC8957703/
