Zobrazeno 1 - 10
of 12
pro vyhledávání: '"David H Burkhardt"'
Publikováno v:
eLife, Vol 6 (2017)
Bacterial mRNAs are organized into operons consisting of discrete open reading frames (ORFs) in a single polycistronic mRNA. Individual ORFs on the mRNA are differentially translated, with rates varying as much as 100-fold. The signals controlling di
Externí odkaz:
https://doaj.org/article/d0fa25ac86db4f76a38945f52bf3b527
Autor:
Virgil A Rhodius, Thomas H Segall‐Shapiro, Brian D Sharon, Amar Ghodasara, Ekaterina Orlova, Hannah Tabakh, David H Burkhardt, Kevin Clancy, Todd C Peterson, Carol A Gross, Christopher A Voigt
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-13 (2013)
Abstract Cells react to their environment through gene regulatory networks. Network integrity requires minimization of undesired crosstalk between their biomolecules. Similar constraints also limit the use of regulators when building synthetic circui
Externí odkaz:
https://doaj.org/article/008a5930ca7040cdb7fd5b0a748f5ffe
Publikováno v:
Journal of Biological Chemistry. 293:777-793
Cellular protein levels are dictated by the balance between gene transcription, mRNA translation, and protein degradation, among other factors. Translation requires the interplay of several RNA hybridization processes, which are expected to be temper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89608a83805657a872f1320c178b22be
https://doi.org/10.1074/jbc.ra117.000284
https://doi.org/10.1074/jbc.ra117.000284
Publikováno v:
The Journal of biological chemistry. 293(3)
Cellular protein levels are dictated by the balance between gene transcription, mRNA translation, and protein degradation, among other factors. Translation requires the interplay of several RNA hybridization processes, which are expected to be temper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5fe687b576acf203739c6bf62ec0d7cd
https://pubmed.ncbi.nlm.nih.gov/29183994
https://pubmed.ncbi.nlm.nih.gov/29183994
Autor:
David H. Burkhardt, Jonathan S. Weissman, Carol A. Gross, Silvi Rouskin, Yan Zhang, Gene-Wei Li
Publikováno v:
PMC
Molecular cell, vol 70, iss 2
Molecular cell, vol 70, iss 2
Temperature influences the structural and functional properties of cellular components, necessitating stress responses to restore homeostasis following temperature shift. Whereas the circuitry controlling the heat shock response is well understood, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de316b0b1f6cc039957b58cd9d15ac6
https://pubmed.ncbi.nlm.nih.gov/29677488
https://pubmed.ncbi.nlm.nih.gov/29677488
Cellular protein levels are dictated by the balance between gene transcription, mRNA translation and protein degradation, among other factors. Cells must manage their proteomes during stress; one way in which they may do so, in principle, is by diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792293e8754721f01e21449ede8c801b
https://doi.org/10.1101/109264
https://doi.org/10.1101/109264
Publikováno v:
Cell, vol 157, iss 3
SummaryQuantitative views of cellular functions require precise measures of rates of biomolecule production, especially proteins—the direct effectors of biological processes. Here, we present a genome-wide approach, based on ribosome profiling, for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1c61588c273374cb8e2f672bb625c2
Autor:
Jonathan S. Weissman, Silvi Rouskin, David H. Burkhardt, Gene-Wei Li, Yan Zhang, Carol A. Gross
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Bacterial mRNAs are organized into operons consisting of discrete open reading frames (ORFs) in a single polycistronic mRNA. Individual ORFs on the mRNA are differentially translated, with rates varying as much as 100-fold. The signals controlling di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad7b7f0e0926c1694653318043f256b
http://hdl.handle.net/1721.1/115142
http://hdl.handle.net/1721.1/115142
Autor:
Amar Ghodasara, Brian D. Sharon, Carol A. Gross, David H. Burkhardt, Thomas H. Segall-Shapiro, Virgil A. Rhodius, Todd Peterson, Hannah Tabakh, Christopher A. Voigt, Ekaterina Orlova, Kevin Clancy
Publikováno v:
Molecular Systems Biology
Nature Publishing Group
Nature Publishing Group
Cells react to their environment through gene regulatory networks. Network integrity requires minimization of undesired crosstalk between their biomolecules. Similar constraints also limit the use of regulators when building synthetic circuits for en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cc1451e1c2e9d082d7c44c6da2b5c5
https://pubmed.ncbi.nlm.nih.gov/24169405
https://pubmed.ncbi.nlm.nih.gov/24169405