Zobrazeno 1 - 10
of 49
pro vyhledávání: '"David H Ardell"'
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Eukaryotes acquired the trait of oxygenic photosynthesis through endosymbiosis of the cyanobacterial progenitor of plastid organelles. Despite recent advances in the phylogenomics of Cyanobacteria, the phylogenetic root of plastid
Externí odkaz:
https://doaj.org/article/70008b7895d44176a38f1d69341a0fe4
Autor:
Paul Kelly, Fatemeh Hadi-Nezhad, Dennis Y Liu, Travis J Lawrence, Roger G Linington, Michael Ibba, David H Ardell
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 2, p e0007983 (2020)
The development of chemotherapies against eukaryotic pathogens is especially challenging because of both the evolutionary conservation of drug targets between host and parasite, and the evolution of strain-dependent drug resistance. There is a strong
Externí odkaz:
https://doaj.org/article/2bcd2afbb04e4533845b81c890cb991e
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 2, p e1003454 (2014)
Molecular phylogenetics and phylogenomics are subject to noise from horizontal gene transfer (HGT) and bias from convergence in macromolecular compositions. Extensive variation in size, structure and base composition of alphaproteobacterial genomes h
Externí odkaz:
https://doaj.org/article/c164ee64e4f64689bfe4086374a06188
Autor:
David H Ardell, Leif A Kirsebom
Publikováno v:
PLoS Computational Biology, Vol 1, Iss 1, p e12 (2005)
In fast-growing microorganisms, a tRNA concentration profile enriched in major isoacceptors selects for the biased usage of cognate codons. This optimizes translational rate for the least mass invested in the translational apparatus. Such translation
Externí odkaz:
https://doaj.org/article/932b448927aa4304bd7de567f8dae605
Autor:
David H. Ardell, Julie Baker Phillips
Publikováno v:
Journal of Molecular Evolution
The evolution of tRNA multigene families remains poorly understood, exhibiting unusual phenomena such as functional conversions of tRNA genes through anticodon shift substitutions. We improved FlyBase tRNA gene annotations from twelve Drosophila spec
Publikováno v:
Bioinformatics
Motivation Structure-conditioned information statistics have proven useful to predict and visualize tRNA Class-Informative Features (CIFs) and their evolutionary divergences. Although permutation P-values can quantify the significance of CIF divergen
Autor:
Julie Baker Phillips, David H. Ardell
The evolution of tRNA multigene families remains poorly understood, exhibiting unusual phenomena such as functional conversions of tRNA genes through anticodon shift substitutions. We improved FlyBase tRNA gene annotations from twelve Drosophila spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dd23b440524534ad1ed058ca668c63e
https://doi.org/10.1101/2020.07.24.220558
https://doi.org/10.1101/2020.07.24.220558
Autor:
Fatemeh Hadi-Nezhad, Travis J Lawrence, Paul Kelly, David H. Ardell, Michael Ibba, Dennis Y. Liu, Roger G. Linington
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 14, Iss 2, p e0007983 (2020)
PLoS Neglected Tropical Diseases, Vol 14, Iss 2, p e0007983 (2020)
The development of chemotherapies against eukaryotic pathogens is especially challenging because of both the evolutionary conservation of drug targets between host and parasite, and the evolution of strain-dependent drug resistance. There is a strong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c86bf90fa74038cb9e6441b22cfe6b
https://doi.org/10.1101/711697
https://doi.org/10.1101/711697
Publikováno v:
BMC Evolutionary Biology
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-13 (2019)
BMC evolutionary biology, vol 19, iss 1
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-13 (2019)
BMC evolutionary biology, vol 19, iss 1
Background Eukaryotes acquired the trait of oxygenic photosynthesis through endosymbiosis of the cyanobacterial progenitor of plastid organelles. Despite recent advances in the phylogenomics of Cyanobacteria, the phylogenetic root of plastids remains
Autor:
Andy Collins-Hed, David H. Ardell
We introduce rugged fitness landscapes called match landscapes for the coevolution of feature-based assortative interactions betweenP≥ 2 cognate pairs of tRNAs and aminoacyl-tRNA synthetases (aaRSs) in aaRS-tRNA interaction networks. Our genotype-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e462140311721e0440444d1b67708fd