Zobrazeno 1 - 5
of 5
pro vyhledávání: '"David Häckes"'
Autor:
Alba Muniesa-Vargas, Carlota Davó-Martínez, Cristina Ribeiro-Silva, Melanie van der Woude, Karen L. Thijssen, Ben Haspels, David Häckes, Ülkem U. Kaynak, Roland Kanaar, Jurgen A. Marteijn, Arjan F. Theil, Maayke M. P. Kuijten, Wim Vermeulen, Hannes Lans
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Congenital nucleotide excision repair (NER) deficiency gives rise to several cancer-prone and/or progeroid disorders. It is not understood how defects in the same DNA repair pathway cause different disease features and severity. Here, we sho
Externí odkaz:
https://doaj.org/article/93db3bf48b4e441887ae6a50279dcc97
Autor:
Katjana Schwab, Luis Coronel, Konstantin Riege, Erika K. Sacramento, Norman Rahnis, David Häckes, Emilio Cirri, Marco Groth, Steve Hoffmann, Martin Fischer
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Recurrently mutated in lymphoid neoplasms, the transcription factor RFX7 is emerging as a tumor suppressor. Previous reports suggested that RFX7 may also have a role in neurological and metabolic disorders. We recently reported that RFX7 res
Externí odkaz:
https://doaj.org/article/49b81b484eb94360a680e1b62c99d075
Autor:
Katjana Schwab, Luis Coronel, Konstantin Riege, Erika K. Sacramento, Norman Rahnis, David Häckes, Emilio Cirri, Marco Groth, Steve Hoffmann, Martin Fischer
Recurrently mutated in lymphoid neoplasms, the transcription factor RFX7 is emerging as a tumor suppressor. Previous reports suggested that RFX7 may also have a role in neurological and metabolic disorders. We recently reported that RFX7 responds to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d0078a83c5e50a718a77a5c215ab6e
https://doi.org/10.1101/2022.12.05.519097
https://doi.org/10.1101/2022.12.05.519097
Publikováno v:
Oncogene. 41(7)
In recent years the tumor suppressor p53 has been increasingly recognized as a potent regulator of the cell metabolism and for its ability to inhibit the critical pro-survival kinases AKT and mTOR. The mechanisms through which p53 controls AKT and mT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226bd5b79ee38fcfa9bdf0a534ecd1f6
https://pubmed.ncbi.nlm.nih.gov/34907345
https://pubmed.ncbi.nlm.nih.gov/34907345
Autor:
Steve Hoffmann, Stephan H. Bernhart, Luis Coronel, Reiner Siebert, Martin Fischer, Silke Förste, Lena Semerau, David Häckes, Katjana Schwab, Konstantin Riege
Publikováno v:
Nucleic Acids Research
Nucleic acids research, 49(13):7437-7456
Nucleic acids research, 49(13):7437-7456
Despite its prominence, the mechanisms through which the tumor suppressor p53 regulates most genes remain unclear. Recently, the regulatory factor X 7 (RFX7) emerged as a suppressor of lymphoid neoplasms, but its regulation and target genes mediating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c23ccaea6fe28945d0112e62d31e221
https://doi.org/10.1101/2021.03.25.436917
https://doi.org/10.1101/2021.03.25.436917