Zobrazeno 1 - 10
of 284
pro vyhledávání: '"David H, Overstreet"'
Autor:
Alan L. Pehrson, Christoffer Bundgaard, Cécile Bétry, Arne Mørk, Nasser Haddjeri, Connie Sanchez, David H. Overstreet
Publikováno v:
Pharmacology Biochemistry and Behavior. 131:136-142
More effective treatments for major depression are needed. We studied if the selective 5-HT3 receptor antagonist ondansetron can potentiate the antidepressant potential of the selective serotonin (5-HT) reuptake inhibitor (SSRI) paroxetine using beha
Publikováno v:
World Journal of Neuroscience. :225-239
This brief review discusses the behavioral consequences of two pharmacologically selected lines of rats. Flinders Sensitive (FSL) and Flinders Resistant (FRL) Lines of rats were selected on the basis of differential hypothermic and behavioral respons
Autor:
Darin J. Knapp, Sarah E. Sinnett, Robert A. Angel, David H. Overstreet, Tiffany A. Wills, Buddy A. Whitman, George R. Breese, Mae Huang
Publikováno v:
Psychopharmacology. 218:179-189
Stress may elevate ethanol drinking and anxiety associated with ethanol drinking. Studies to identify relevant neurobiological substrates are needed.To assess roles of brain regions in corticotrophin releasing factor (CRF) effects on stressor-enhance
Publikováno v:
Alcoholism: Clinical and Experimental Research. 34:1603-1612
Adolescence is known to be a time of increased use of alcohol, and this use is the strongest predictor of alcohol dependence in adulthood (Grant, 1998; Grant and Dawson, 1997). Additionally, the dependency course (time between initial use and depende
Autor:
Ivan Diamond, Maria Pia Arolfo, Tao Guoxin, Bert L. Vallee, Louis G. Lange, Justin T. Gass, Wing Ming Keung, Emanuel Rubin, Helen Anni, Brent Blackburn, Clyde W. Hodge, Peidong Fan, David H. Overstreet, Andrew J Lawrence, Lina Yao, Joyce Besheer, Jeff Zablocki, Kwan Leung, M. Foster Olive
Publikováno v:
Alcohol Clin Exp Res
Background: Inherited human aldehyde dehydrogenase 2 (ALDH-2) deficiency reduces the risk for alcoholism. Kudzu plants and extracts have been used for 1,000 years in traditional Chinese medicine to treat alcoholism. Kudzu contains daidzin, which inhi
Autor:
Mae M. Huang, Darin J. Knapp, Jean Rivier, George R. Breese, Tiffany A. Wills, Wylie Vale, Robert A. Angel, David H. Overstreet, Montserrat Navarro
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 332:298-307
In abstinent alcoholics, stress induces negative affect—a response linked to craving and relapse. In rats, repeated stresses at weekly intervals before 5-day ethanol diet sensitize withdrawal-induced anxiety-like behavior (“anxiety”) that is bl
Autor:
Matthew S. McMurray, Thomas M. Jarrett, Sarah K. Williams, Cheryl H. Walker, David H. Overstreet, Elizabeth Cox, Josephine M. Johns, Emily E. Fay
Publikováno v:
Neurotoxicology and Teratology. 31:291-302
Ethanol consumption and smoking during pregnancy are common, despite the known adverse effects on the fetus. The teratogenicity of each drug independently is well established; however, the effects of concurrent exposure to ethanol and nicotine in pre
Publikováno v:
Alcoholism: Clinical and Experimental Research. 33:1366-1373
Background: Since 1994, when naltrexone (Revia®) was approved by the FDA for the treatment of alcoholism, only 2 other drugs (Campral® and Topamax®) have been approved for alcoholism treatment. However, various experimental drugs, including antiep
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33:398-402
A strong positive association between depression and alcoholism is evident in epidemiological studies. Curiously, the incidence of smoking (nicotine intake) is also very high among depressed individuals. Because neuronal nicotinic receptors have been
Autor:
Laxminarayan G. Hegde, Mary W. Walker, Vrej Jubian, Mariusz Papp, Mohammad R. Marzabadi, Douglas A. Craig, Christophe P. G. Gerald, David H. Overstreet, Silke Miller, Gamini Chandrasena, Huailing Zhong, Toni D. Wolinsky, Douglas A. Marsteller, Xinyan Huang
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 328:900-911
Neuropeptide Y (NPY) regulates physiological processes via receptor subtypes (Y1, Y2, Y4, Y5, and y6). The Y5 receptor is well known for its role in appetite. Based on expression in the limbic system, we hypothesized that the Y5 receptor might also m