Zobrazeno 1 - 10
of 85
pro vyhledávání: '"David H, Farb"'
Autor:
Marcia H. Ratner, David H. Farb
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Adverse effects of drugs on the human nervous system are rarely possible to anticipate based on preclinical neurotoxicity data, thus propagating the centuries long single most important obstacle to drug discovery and development for disorders of the
Externí odkaz:
https://doaj.org/article/90f8ae6d47374477afffd9e16719b00b
Autor:
Marcia H. Ratner, Scott S. Downing, Ouyang Guo, KathrynAnn E. Odamah, Tara M. Stewart, Vidhya Kumaresan, R. Jonathan Robitsek, Weiming Xia, David H. Farb
Publikováno v:
Heliyon, Vol 7, Iss 9, Pp e07895- (2021)
Decades of research attempting to slow the onset of Alzheimer's disease (AD) indicates that a better understanding of memory will be key to the discovery of effective therapeutic approaches. Here, we ask whether prodromal neural network dysfunction m
Externí odkaz:
https://doaj.org/article/7e085454662b404193745061c47c2261
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Memory dysfunction is a symptomatic feature of many neurologic and neuropsychiatric disorders; however, the basic underlying mechanisms of memory and altered states of circuitry function associated with disorders of memory remain a vast unexplored te
Externí odkaz:
https://doaj.org/article/a3e2c81de730418a9fabff83cd06049a
Autor:
Marcia Ratner, David H. Farb
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.
Autor:
Marcia H, Ratner, David H, Farb
Publikováno v:
Frontiers in toxicology. 4
Adverse effects of drugs on the human nervous system are rarely possible to anticipate based on preclinical neurotoxicity data, thus propagating the centuries long single most important obstacle to drug discovery and development for disorders of the
Autor:
David H. Farb, Tara M. Stewart, R. Jonathan Robitsek, Weiming Xia, Vidhya Kumaresan, Scott S. Downing, Ouyang Guo, Marcia H. Ratner, KathrynAnn E. Odamah
Publikováno v:
Heliyon, Vol 7, Iss 9, Pp e07895-(2021)
Decades of research attempting to slow the onset of Alzheimer's disease (AD) indicates that a better understanding of memory will be key to the discovery of effective therapeutic approaches. Here, we ask whether prodromal neural network dysfunction m
Autor:
John F. Cryan, David H. Farb, Norman G. Bowery, Wolfgang Foestl, Klemens Kaupmann, S.J. Enna, Bernhard Bettler, Jean-Philippe Pin
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
Functional GABAB receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on GABAB receptors [11, 71]) are formed from the heterodimerization of two similar 7TM subunits termed GABAB1 and GABAB2 [11, 70, 28, 71, 87]. GABAB receptors are widesp
Autor:
Klemens Kaupmann, Bernhard Bettler, Norman G. Bowery, David H. Farb, S.J. Enna, Jean-Philippe Pin, Wolfgang Foestl, John F. Cryan
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2019
Functional GABAB receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on GABAB receptors [11, 72]) are formed from the heterodimerization of two similar 7TM subunits termed GABAB1 and GABAB2 [11, 71, 28, 72, 85]. GABAB receptors are widesp
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Frontiers in Endocrinology
Frontiers in Endocrinology
Memory dysfunction is a symptomatic feature of many neurologic and neuropsychiatric disorders; however, the basic underlying mechanisms of memory and altered states of circuitry function associated with disorders of memory remain a vast unexplored te
Publikováno v:
Hippocampus. 25:1541-1555
Learning and memory deficits associated with age-related mild cognitive impairment have long been attributed to impaired processing within the hippocampus. Hyperactivity within the hippocampal CA3 region that is associated with aging is mediated in p