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pro vyhledávání: '"David Gordon Mcdowell"'
Autor:
Lynda J. Brown, John M. Mellor, Tom Brown, Neil Dobson, David John French, David Gordon Mcdowell
An FMOC-protected 2'-hydroxyethyl uridine phosphoramidite has been used to synthesise fluorescein-labelled HyBeacon probes and "FAM-ROX" dual-labelled fluorogenic oligonucleotides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbe240506f32f2c1555aebd62250b33
https://doi.org/10.1039/b302855k
https://doi.org/10.1039/b302855k
Autor:
Kenneth T. Douglas, David John French, Elena V. Bichenkova, David Gordon Mcdowell, Pranab K. Bhadra, Abigail H. R. Marks, Richard A. Bryce
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 23:49-62
HyBeacons, novel DNA probes for ultra-rapid detection of single nucleotide polymorphisms, contain a fluorophore covalently attached via a linker group to an internal nucleotide. As the probe does not require a quencher or self-complementarity to func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995b17efdbed9452cb0e2e1e0a83b997
https://doi.org/10.1080/07391102.2005.10507046
https://doi.org/10.1080/07391102.2005.10507046
Publikováno v:
Methods in Molecular Biology ISBN: 9781588297006
HyBeacon probes are single-stranded oligonucleotides with one or more internal base(s) labeled with a fluorescent dye. When a probe forms a duplex with its target sequence, the level of fluorescence emission increases considerably. HyBeacons have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26e08af97ff98d7c9e2df0ac32be3832
https://doi.org/10.1007/978-1-60327-040-3_12
https://doi.org/10.1007/978-1-60327-040-3_12
Publikováno v:
BMC Infectious Diseases
BMC Infectious Diseases, Vol 7, Iss 1, p 90 (2007)
BMC Infectious Diseases, Vol 7, Iss 1, p 90 (2007)
Background Resistance and susceptibility to scrapie has been associated with single nucleotide polymorphisms located within codons 136, 154 and 171 of the ovine prion protein gene (PRNP). Dual-labelled HyBeacon probes were developed to analyse single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e7c785af239a0c0c4d289b1fa4add0
http://europepmc.org/articles/PMC1994165
http://europepmc.org/articles/PMC1994165