Zobrazeno 1 - 10
of 13
pro vyhledávání: '"David Gonzalez-Martin"'
Autor:
David Gonzalez-Martinez, Lee Roth, Thomas R. Mumford, Juan Guan, Anh Le, Robert C. Doebele, Bo Huang, Asmin Tulpule, Magdalena Niewiadomska-Bugaj, Trever G. Bivona, Lukasz J. Bugaj
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Drug resistance remains a challenge for targeted therapy of cancers driven by EML4-ALK and related fusion oncogenes. EML4-ALK forms cytoplasmic protein condensates, which result from networks of interactions between oncogene and adapter prot
Externí odkaz:
https://doaj.org/article/369d4a9ed829495a9689692c1e1918f3
Publikováno v:
Journal of the Foot & Ankle, Vol 15, Iss 3 (2021)
This study proposes an update on conservative treatment of hallux rigidus based on scientific evidence. This is a narrative review of 19 articles that analyzed conservative treatment of hallux rigidus in its different modalities. Conservative treatme
Autor:
Gonzalo de Cabo, M.D., Pablo Ramos-Murillo, M.D., David González-Martín, M.D., Ph.D., Nuria Álvarez-Benito, M.D., Francisco Poyato-Núñez, M.D., Silvia Virginia Campesino-Nieto, M.D., Manuel Leyes, M.D., Ph.D.
Publikováno v:
Arthroscopy Techniques, Vol 13, Iss 11, Pp 103115- (2024)
Multidirectional shoulder instability represents an ongoing challenge for orthopaedic surgeons, and multiple techniques have been described to treat this condition. Posterior glenoid dysplasia is a known risk factor for posterior instability as well
Externí odkaz:
https://doaj.org/article/f83883bd923d42e1b191f4451b9339e3
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 7; Pages: 1851
Hip fracture is the most feared complication of osteoporosis, producing up to 30% mortality at the first year. With the aging of society, it is increasingly common to deal with ethical dilemmas that involve decision making in the elderly patient with
Publikováno v:
Journal of the Foot & Ankle, Vol 15, Iss 3 (2021)
This study performs a literature review on the treatment of hallux rigidus and proposes a treatment algorithm.This literature systematic review expanded a similar study conducted in 2014 by the authors and analyzed the levels of recommendation accord
Autor:
Alexander Chan, Rebecca M. Haley, Mohd Altaf Najar, David Gonzalez-Martinez, Lukasz J. Bugaj, George M. Burslem, Michael J. Mitchell, Andrew Tsourkas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Recently, targeted degradation has emerged as a powerful therapeutic modality. Relying on “event-driven” pharmacology, proteolysis targeting chimeras (PROTACs) can degrade targets and are superior to conventional inhibitors against undru
Externí odkaz:
https://doaj.org/article/c8e03480a79f42f1b05ddadc6ec0b9d3
Autor:
William Benman, Saachi Datta, David Gonzalez-Martinez, Gloria Lee, Juliette Hooper, Grace Qian, Gabrielle Leavitt, Lana Salloum, Gabrielle Ho, Sharvari Mhatre, Michael S. Magaraci, Michael Patterson, Sevile G. Mannickarottu, Saurabh Malani, Jose L. Avalos, Brian Y. Chow, Lukasz J. Bugaj
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract The ability to perform sophisticated, high-throughput optogenetic experiments has been greatly enhanced by recent open-source illumination devices that allow independent programming of light patterns in single wells of microwell plates. Howe
Externí odkaz:
https://doaj.org/article/3efa70a4a8c0485dbec94aa00969e823
Autor:
Gonzalo de Cabo, M.D., Nuria Álvarez-Benito, M.D., Pablo Ramos-Murillo, M.D., Francisco Poyato-Núñez, M.D., David González-Martín, M.D., Ph.D., Manuel Leyes, M.D., Ph.D.
Publikováno v:
Arthroscopy Techniques, Vol 12, Iss 12, Pp e2153-e2159 (2023)
Several arthroscopic techniques to treat anterior shoulder instability have been described. Bankart repair may be insufficient in cases with some degree of bone loss, and arthroscopic Latarjet is technically challenging. It is not rare to find at the
Externí odkaz:
https://doaj.org/article/004273e1b2264574acd6607f543405de
Autor:
Gonzalo de Cabo, M.D., David González-Martín, M.D., Ph.D., Alberto Martínez de Aragón, M.D., Juan A. Rubio, M.D., Manuel Leyes, M.D., Ph.D.
Publikováno v:
Arthroscopy Techniques, Vol 12, Iss 7, Pp e1233-e1240 (2023)
Massive irreparable cuff tears may represent as many as 20% to 40% of total cases of operated rotator cuff tears and can be a challenging clinical problem. Many treatment options have been proposed for their treatment. Among these options, latissimus
Externí odkaz:
https://doaj.org/article/647ff2594bb64ce29c847d6899d7b011
Autor:
Gonzalo de Cabo, M.D., David González-Martín, M.D., Ph.D., Alberto Martínez de Aragón, M.D., Juan A. Rubio, M.D., Manuel Leyes, M.D., Ph.D.
Publikováno v:
Arthroscopy Techniques, Vol 12, Iss 3, Pp e387-e394 (2023)
Anterior shoulder instability remains one of the main indications for shoulder surgery. We present a modified way of treating anterior shoulder instability in the beach-chair position from an anterior arthroscopic approach through the rotator interva
Externí odkaz:
https://doaj.org/article/8d044c31d5224a489064cb8341c131a3