Zobrazeno 1 - 10
of 178
pro vyhledávání: '"David Gomez‐Cabrero"'
Autor:
Sara Palomino-Echeverria, Estefania Huergo, Asier Ortega-Legarreta, Eva M. Uson Raposo, Ferran Aguilar, Carlos de la Peña-Ramirez, Cristina López-Vicario, Carlo Alessandria, Wim Laleman, Alberto Queiroz Farias, Richard Moreau, Javier Fernandez, Vicente Arroyo, Paolo Caraceni, Vincenzo Lagani, Cristina Sánchez-Garrido, Joan Clària, Jesper Tegner, Jonel Trebicka, Narsis A. Kiani, Nuria Planell, Pierre-Emmanuel Rautou, David Gomez-Cabrero
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Patient heterogeneity poses significant challenges for managing individuals and designing clinical trials, especially in complex diseases. Existing classifications rely on outcome-predicting scores, potentially overlooking crucial
Externí odkaz:
https://doaj.org/article/afc33b047ee34914a86a10e0483c2fdb
Autor:
Maryam Alowaysi, Robert Lehmann, Mohammad Al-Shehri, Moayad Baadhaim, Hajar Alzahrani, Doaa Aboalola, Asima Zia, Dalal Malibari, Mustafa Daghestani, Khaled Alghamdi, Ali Haneef, Dunia Jawdat, Fahad Hakami, David Gomez-Cabrero, Jesper Tegner, Khaled Alsayegh
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Human iPSCs' derivation and use in clinical studies are transforming medicine. Yet, there is a high cost and long waiting time associated with autologous iPS-based cellular therapy, and the genetic engineering of hypo-immunogenic
Externí odkaz:
https://doaj.org/article/6dd0a040a789495da7871c502a54028c
Autor:
Lara Kular, Ewoud Ewing, Maria Needhamsen, Majid Pahlevan Kakhki, Ruxandra Covacu, David Gomez-Cabrero, Lou Brundin, Maja Jagodic
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1311-1330 (2022)
Multiple Sclerosis (MS), the leading cause of non-traumatic neurological disability in young adults, is a chronic inflammatory and neurodegenerative disease of the central nervous system (CNS). Due to the poor accessibility to the target organ, CNS-c
Externí odkaz:
https://doaj.org/article/c51728ccf3754d1c82a7db4b5d73b72f
Autor:
Miren Lasaga, Paula Río, Amaia Vilas-Zornoza, Nuria Planell, Susana Navarro, Diego Alignani, Beatriz Fernández-Varas, Daniel Mouzo, Josune Zubicaray, Roser M. Pujol, Eileen Nicoletti, Jonathan D. Schwartz, Julián Sevilla, Marina Ainciburi, Asier Ullate-Agote, Jordi Surrallés, Rosario Perona, Leandro Sastre, Felipe Prosper, David Gomez-Cabrero, Juan A. Bueren
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Clinical trials have shown that lentiviral-mediated gene therapy can ameliorate bone marrow failure (BMF) in nonconditioned Fanconi anemia (FA) patients resulting from the proliferative advantage of corrected FA hematopoietic stem and progenitor cell
Externí odkaz:
https://doaj.org/article/d53a95898f024aef96171022924acc08
Autor:
Marina Ainciburu, Teresa Ezponda, Nerea Berastegui, Ana Alfonso-Pierola, Amaia Vilas-Zornoza, Patxi San Martin-Uriz, Diego Alignani, Jose Lamo-Espinosa, Mikel San-Julian, Tamara Jiménez-Solas, Felix Lopez, Sandra Muntion, Fermin Sanchez-Guijo, Antonieta Molero, Julia Montoro, Guillermo Serrano, Aintzane Diaz-Mazkiaran, Miren Lasaga, David Gomez-Cabrero, Maria Diez-Campelo, David Valcarcel, Mikel Hernaez, Juan P Romero, Felipe Prosper
Publikováno v:
eLife, Vol 12 (2023)
Early hematopoiesis is a continuous process in which hematopoietic stem and progenitor cells (HSPCs) gradually differentiate toward specific lineages. Aging and myeloid malignant transformation are characterized by changes in the composition and regu
Externí odkaz:
https://doaj.org/article/3e9c063b4a474f658aaf2538b69955f6
Autor:
Sumeer Ahmad Khan, Robert Lehmann, Xabier Martinez-de-Morentin, Alberto Maillo, Vincenzo Lagani, Narsis A Kiani, David Gomez-Cabrero, Jesper Tegner
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281315 (2023)
Recent progress in Single-Cell Genomics has produced different library protocols and techniques for molecular profiling. We formulate a unifying, data-driven, integrative, and predictive methodology for different libraries, samples, and paired-unpair
Externí odkaz:
https://doaj.org/article/018fa0f3e61941afa9def054ff5a72ae
Autor:
Lara Kular, Dennis Klose, Amaya Urdánoz-Casado, Ewoud Ewing, Nuria Planell, David Gomez-Cabrero, Maria Needhamsen, Maja Jagodic
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundMultiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS) characterized by irreversible disability at later progressive stages. A growing body of evidence suggests that disease progressi
Externí odkaz:
https://doaj.org/article/aa9b6d4c84d341598d715e8337737b59
Autor:
Rasmus Magnusson, Olof Rundquist, Min Jung Kim, Sandra Hellberg, Chan Hyun Na, Mikael Benson, David Gomez-Cabrero, Ingrid Kockum, Jesper N. Tegnér, Fredrik Piehl, Maja Jagodic, Johan Mellergård, Claudio Altafini, Jan Ernerudh, Maria C. Jenmalm, Colm E. Nestor, Min-Sik Kim, Mika Gustafsson
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Profiling of mRNA expression is an important method to identify biomarkers but complicated by limited correlations between mRNA expression and protein abundance. We hypothesised that these correlations could be improved by mathematical models based o
Externí odkaz:
https://doaj.org/article/382998380f194fbbbb24e92340e5edd7
Autor:
Abeer Shaalan, Sunjae Lee, Catherine Feart, Esther Garcia-Esquinas, David Gomez-Cabrero, Esther Lopez-Garcia, Martine Morzel, Eric Neyraud, Fernando Rodriguez-Artalejo, Ricarda Streich, Gordon Proctor
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
The Mediterranean diet (MedDiet) represents the traditional food consumption patterns of people living in countries bordering the Mediterranean Sea and is associated with a reduced incidence of obesity and type-2 diabetes mellitus (T2DM). The objecti
Externí odkaz:
https://doaj.org/article/d400fc8b98d04b55995d5d5f615e650c
Autor:
Jin Ye, Isabel A. Calvo, Itziar Cenzano, Amaia Vilas, Xabier Martinez-de-Morentin, Miren Lasaga, Diego Alignani, Bruno Paiva, Ana C. Viñado, Patxi San Martin-Uriz, Juan P. Romero, Delia Quilez Agreda, Marta Miñana Barrios, Ignacio Sancho-González, Gabriele Todisco, Luca Malcovati, Nuria Planell, Borja Saez, Jesper N. Tegner, Felipe Prosper, David Gomez-Cabrero
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104225- (2022)
Summary: Understanding the regulation of normal and malignant human hematopoiesis requires comprehensive cell atlas of the hematopoietic stem cell (HSC) regulatory microenvironment. Here, we develop a tailored bioinformatic pipeline to integrate publ
Externí odkaz:
https://doaj.org/article/ccde1bb022e24ec1a1f2e788e69807b2