Zobrazeno 1 - 10
of 43
pro vyhledávání: '"David Goldeck"'
Autor:
David Goldeck, Claudia Schulte, Marcia Cristina Teixeira dos Santos, Dieter Scheller, Lilly Öttinger, Graham Pawelec, Christian Deuschle, Daniela Berg, Andre Nogueira da Costa, Walter Maetzler
Publikováno v:
Journal of Ageing and Longevity, Vol 3, Iss 1, Pp 1-10 (2022)
Immune cells are thought to be involved in a destructive cycle of sterile cerebral inflammatory responses in neurodegenerative diseases such as Parkinson’s Disease (PD). Despite their peripheral origin, immune cells may enter the CNS due to impaire
Externí odkaz:
https://doaj.org/article/865ea649649542adb5276a4db21b9db7
Autor:
Julia Sbierski-Kind, David Goldeck, Nikolaus Buchmann, Joachim Spranger, Hans-Dieter Volk, Elisabeth Steinhagen-Thiessen, Graham Pawelec, Ilja Demuth, Dominik Spira
Publikováno v:
Immunity & Ageing, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background Obesity is associated with chronic low-grade inflammation leading to metabolic and cardiovascular diseases, but a subset of obese individuals is considered insulin sensitive (IS). The underlying pathophysiologic mechanisms remain
Externí odkaz:
https://doaj.org/article/7426f08b681a43c2b985733f0d298f56
Autor:
Fakhri Hassouneh, David Goldeck, Alejandra Pera, Diana van Heemst, P. Eline Slagboom, Graham Pawelec, Rafael Solana
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9973 (2021)
Cytomegalovirus (CMV) latent infection and aging contribute to alterations in the function and phenotype of the T-cell pool. We have demonstrated that CMV-seropositivity is associated with the expansion of polyfunctional CD57+ T-cells in young and mi
Externí odkaz:
https://doaj.org/article/efa038739fd04c029cfcc80743bc341c
Autor:
David Goldeck, Lisbeth Aagaard Larsen, Kaare Christensen, Klaus Hamprecht, Lilly Öttinger, Karin Hähnel, Graham Pawelec
Publikováno v:
Pathogens, Vol 10, Iss 8, p 963 (2021)
Frequencies and proportions of regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSCs) in peripheral blood may be informative biomarkers for certain disease states. The influence of genetics and lifetime pathogen exposures on Treg and
Externí odkaz:
https://doaj.org/article/45e9e06de78249f19918ae52dc56dc87
Autor:
David Goldeck, Dana M. Perry, Jack W. P. Hayes, Luke P. M. Johnson, Jordan E. Young, Parimal Roychoudhury, Elle L. McLuskey, Katy Moffat, Arjen Q. Bakker, Mark J. Kwakkenbos, Jean-Pierre Frossard, Raymond R. R. Rowland, Michael P. Murtaugh, Simon P. Graham
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The rapid evolution of porcine reproductive and respiratory syndrome viruses (PRRSV) poses a major challenge to effective disease control since available vaccines show variable efficacy against divergent strains. Knowledge of the antigenic targets of
Externí odkaz:
https://doaj.org/article/dadacc05142c4eaf8915c7523c7afee9
Autor:
Nikolaus Buchmann, Ursula Kassner, Kristina Norman, David Goldeck, Rahel Eckardt, Graham Pawelec, Elisabeth Steinhagen-Thiessen, Ilja Demuth
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139040 (2015)
Reduced pulmonary function and elevated serum cholesterol levels are recognized risk factors for cardiovascular disease. Currently, there is some controversy concerning relationships between cholesterol, LDL-cholesterol, HDL-cholesterol, serum trigly
Externí odkaz:
https://doaj.org/article/ea8574f72c5f44e5844ba04f60e7a0da
Autor:
David Goldeck, Anis Larbi, Mariavaleria Pellicanó, Iftikhar Alam, Inga Zerr, Christian Schmidt, Tamas Fulop, Graham Pawelec
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66664 (2013)
Although primarily a neurological complaint, systemic inflammation is present in Alzheimer's Disease, with higher than normal levels of proinflammatory cytokines and chemokines in the periphery as well as the brain. A gradient of these factors may en
Externí odkaz:
https://doaj.org/article/0ff1bda3e1054c1f9c1c4c185ed3e958
Autor:
David Goldeck, Farmen K, Sara K. Nissen, Kathrin Brockmann, Marina Romero-Ramos, Claudia Schulte, Carstensen M
Publikováno v:
Konstantin Nissen, S, Farmen, K, Carstensen, M, Schulte, C, Goldeck, D, Brockmann, K & Romero-Ramos, M 2022, ' Changes in CD163+, CD11b+, and CCR2+ peripheral monocytes relate to Parkinson's disease and cognition ', Brain, Behavior, and Immunity, vol. 101, pp. 182-193 . https://doi.org/10.1016/j.bbi.2022.01.005
Brain, behavior and immunity 101, 182-193 (2022). doi:10.1016/j.bbi.2022.01.005
Brain, behavior and immunity 101, 182-193 (2022). doi:10.1016/j.bbi.2022.01.005
1.AbstractAlpha-synuclein pathology is associated with immune activation and neurodegeneration in Parkinson’s disease. The immune activation involves not only microglia but also peripheral immune cells, such as mononuclear phagocytes found in blood
Autor:
David Goldeck, Catharina Matheï, Jean-Marie Degryse, Klaus Hamprecht, Graham Pawelec, Bert Vaes, Wim Adriaensen, Lilly Oettinger, Gijs Van Pottelbergh
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 76, no. 8, p. 1356-1361 (2021)
Frailty has been related to inflammaging and certain immune parameters. In previous analyses of participants older than 80 years of age in the longitudinal BELFRAIL cohort study, the main focus was on T-cell phenotypes and the association with cytome
Autor:
Rafael Solana, Alejandra Pera, David Goldeck, P. Eline Slagboom, Diana van Heemst, Fakhri Hassouneh, Graham Pawelec
Publikováno v:
International Journal of Molecular Sciences, 22(18). MDPI
International Journal of Molecular Sciences 22(18), 9973 (2021)
Helvia. Repositorio Institucional de la Universidad de Córdoba
instname
International Journal of Molecular Sciences, Vol 22, Iss 9973, p 9973 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences 22(18), 9973 (2021)
Helvia. Repositorio Institucional de la Universidad de Córdoba
instname
International Journal of Molecular Sciences, Vol 22, Iss 9973, p 9973 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 18
Cytomegalovirus (CMV) latent infection and aging contribute to alterations in the function and phenotype of the T-cell pool. We have demonstrated that CMV-seropositivity is associated with the expansion of polyfunctional CD57+ T-cells in young and mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5584ac81a6e207d42208e21c101c587
https://hdl.handle.net/10668/18580
https://hdl.handle.net/10668/18580