Zobrazeno 1 - 10
of 1 800
pro vyhledávání: '"David Go"'
Autor:
Amy McCaughey-Chapman, Anne Lieke Burgers, Catharina Combrinck, Laura Marriott, David Gordon, Bronwen Connor
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Huntington’s disease (HD) is a genetic neurological disorder predominantly characterised by the progressive loss of GABAergic medium spiny neurons in the striatum resulting in motor dysfunction. One potential strategy for the tr
Externí odkaz:
https://doaj.org/article/53284fd4f2534acabd19ab512f31d9be
Autor:
Carlos Eduardo Rey Chaves, Sebastián Díaz, David Gómez Garnica, Oscar Cardenas, Paula Noguera, Manuela Ortíz Marín, Vanessa Velandia, Danny Conde, María Camila Rojas Gómez, María Gómez Zuleta
Publikováno v:
BMC Surgery, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background Splenectomy indications are well documented; however, several infectious complications and potentially life-threatening conditions could arise after splenectomy. We aim to describe a 20-year single-center experience of postoperati
Externí odkaz:
https://doaj.org/article/6a410d4f78d04cbc8a99821fc5c6a322
Autor:
David Gonzalez-Martinez, Lee Roth, Thomas R. Mumford, Juan Guan, Anh Le, Robert C. Doebele, Bo Huang, Asmin Tulpule, Magdalena Niewiadomska-Bugaj, Trever G. Bivona, Lukasz J. Bugaj
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Drug resistance remains a challenge for targeted therapy of cancers driven by EML4-ALK and related fusion oncogenes. EML4-ALK forms cytoplasmic protein condensates, which result from networks of interactions between oncogene and adapter prot
Externí odkaz:
https://doaj.org/article/369d4a9ed829495a9689692c1e1918f3
Publikováno v:
Journal of Orthopaedic Translation, Vol 49, Iss , Pp 107-118 (2024)
Background/Objective: Active vitamin D insufficiency accelerates the development of osteoporosis, with senescent bone cells and the senescence-associated secretory phenotype (SASP) playing crucial roles. This study aimed to investigate whether the se
Externí odkaz:
https://doaj.org/article/3cc72d33794d4a38ab28e7dd8c243e54
Autor:
Maria Francesca Di Feo, Ali Oghabian, Ella Nippala, Mathias Gautel, Heinz Jungbluth, Francesca Forzano, Edoardo Malfatti, Claudia Castiglioni, Ilona Krey, David Gomez Andres, Angela F. Brady, Maria Iascone, Anna Cereda, Lidia Pezzani, Daniel Natera De Benito, Andres Nascimiento Osorio, Berta Estévez Arias, Sergei A. Kurbatov, Tania Attie‐Bitach, Sheela Nampoothiri, Erin Ryan, Michelle Morrow, Svetlana Gorokhova, Brigitte Chabrol, Juha Sinisalo, Heli Tolppanen, Johanna Tolva, Francina Munell, Jessica Camacho Soriano, Maria Angeles Sanchez Duran, Mridul Johari, Homa Tajsharghi, Peter Hackman, Bjarne Udd, Marco Savarese
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 10, Pp 2745-2755 (2024)
Abstract Objective Biallelic titin truncating variants (TTNtv) have been associated with a wide phenotypic spectrum, ranging from complex prenatal muscle diseases with dysmorphic features to adult‐onset limb‐girdle muscular dystrophy, with or wit
Externí odkaz:
https://doaj.org/article/56fcca32800d4caeb1e23bc0b7d6e783
Autor:
Amit Kumar Rai, Natarajaseenivasan Suriya Muthukumaran, Noemi Nisini, Tiffany Lee, Ioannis D. Kyriazis, Claudio de Lucia, Michela Piedepalumbo, Rajika Roy, Shizuka Uchida, Konstantinos Drosatos, Malik Bisserier, Rajesh Katare, David Goukassian, Raj Kishore, Venkata Naga Srikanth Garikipati
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract More than 10% of adults in the United States have type 2 diabetes mellitus (DM) with a 2–4 times higher prevalence of ischemic heart disease than the non-diabetics. Despite extensive research approaches to limit this life-threatening condi
Externí odkaz:
https://doaj.org/article/de90f5e45f344d688ac06acf5133d832
Autor:
Pamela C. Köster, Ana M. Figueiredo, Jenny G. Maloney, Alejandro Dashti, Begoña Bailo, Rita T. Torres, Carlos Fonseca, Atle Mysterud, Miguel Á. Habela, Antonio Rivero-Juarez, Joaquín Vicente, Emmanuel Serrano, Maria C. Arnal, Daniel Fernández de Luco, José A. Armenteros, Ana Balseiro, Guillermo A. Cardona, João Carvalho, Dário Hipólito, Joana Fernandes, Josman D. Palmeira, Rafael Calero-Bernal, David González-Barrio, Monica Santin, David Carmena
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-12 (2024)
Abstract The ongoing increase in wild boar populations across Europe has fostered human–wildlife conflicts, including the transmission of emerging pathogens with zoonotic importance. Blastocystis is a ubiquitous, faecal-oral transmitted protist tha
Externí odkaz:
https://doaj.org/article/0b760eb0d6fe4b99a416a325f6a561ff
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract University entrance test-takers are a vulnerable group of students transitioning from adolescence to youth, a peak time for adopting unhealthy behaviors. However, limited studies investigate substance use behaviors among this group. This stu
Externí odkaz:
https://doaj.org/article/7021cbfd1913469aa9212ab68db05c15
Publikováno v:
Journal of Urban Research, Vol 48, Iss 4, Pp 47-64 (2024)
تتناول هذه الورقة البحثية البعد الصوتي لمدن الواحات وتوضح كيف ان الصوت العمراني يمكن ان يعزز ديناميكية جماعية، مما يمكن فريقًا متعدد الت
Externí odkaz:
https://doaj.org/article/11730004e3db4f49bc2a34902d3b9b43
Autor:
Jeremy W. Luk, Matthew F. Thompson, Laura A. Novak, Bethany L. Stangl, Melanie L. Schwandt, David Goldman, Vijay A. Ramchandani, Nancy Diazgranados
Publikováno v:
Psychiatric Research and Clinical Practice, Vol 6, Iss 3, Pp 78-86 (2024)
Objective Individuals with a history of suicidality may be especially vulnerable to the adverse impact of COVID‐related stressors, but this vulnerability has not been demonstrated. This study examined the longitudinal effects of suicidality history
Externí odkaz:
https://doaj.org/article/a72ddcf572cb49c3adc981931c2cbd1c