Zobrazeno 1 - 10
of 21
pro vyhledávání: '"David Gacquer"'
Autor:
Debora Fumagalli, David Gacquer, Françoise Rothé, Anne Lefort, Frederick Libert, David Brown, Naima Kheddoumi, Adam Shlien, Tomasz Konopka, Roberto Salgado, Denis Larsimont, Kornelia Polyak, Karen Willard-Gallo, Christine Desmedt, Martine Piccart, Marc Abramowicz, Peter J. Campbell, Christos Sotiriou, Vincent Detours
Publikováno v:
Cell Reports, Vol 13, Iss 2, Pp 277-289 (2015)
Little is known about how RNA editing operates in cancer. Transcriptome analysis of 68 normal and cancerous breast tissues revealed that the editing enzyme ADAR acts uniformly, on the same loci, across tissues. In controlled ADAR expression experimen
Externí odkaz:
https://doaj.org/article/a873930351a44a2ba558664b8f0f36d9
Autor:
Matteo Serra, Laetitia Collet, Mattia Rediti, Frédéric Lifrange, David Venet, Xiaoxiao Wang, Delphine Vincent, Ghizlane Rouas, Danai Fimereli, David Gacquer, Andrea Joaquin Garcia, Isabelle Veys, Ligia Craciun, Denis Larsimont, Miikka Vikkula, François Duhoux, Françoise Rothé, Christos Sotiriou
Publikováno v:
Cancer Research. 82:P1-05
Background: Invasive lobular breast carcinoma (ILC) represents 5 to 15% of all invasive breast cancers (BCs). Here, we aim to investigate inter- and intra-tumor heterogeneity in terms of microenvironment composition, PAM50 molecular classification an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::332b2c61d5288e22b2e14e09cd296c92
https://doi.org/10.1158/1538-7445.sabcs21-p1-05-03
https://doi.org/10.1158/1538-7445.sabcs21-p1-05-03
Autor:
Xiaoxiao Wang, David Venet, Frédéric Lifrange, Denis Larsimont, Mattia Rediti, Linnea Stenbeck, David Gacquer, Floriane Dupont, Ghizlane Rouas, Matteo Serra, Joakim Lundeberg, Françoise Rothé, Christos Sotiriou
Publikováno v:
Cancer Research. 83:PD4-01
Background Triple negative breast cancer (TNBC) is a heterogeneous disease characterized by at least five molecular subtypes, namely basal like (BL), immunomodulatory (IM), luminal androgen receptor (LAR), mesenchymal (M) and mesenchymal stem like (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::014b15f85f7c619990ae17dcefa2cbe7
https://doi.org/10.1158/1538-7445.sabcs22-pd4-01
https://doi.org/10.1158/1538-7445.sabcs22-pd4-01
Autor:
Carine Maenhaut, Bernard Corvilain, David Gacquer, Laura Van Den Eeckhaute, Laure Twyffels, Aglaia Kyrilli, Vincent Detours, Anne Lefort, Frédérick Libert, Françoise Miot, Xavier De Deken, Jacques Emile Dumont, Aurélie Strickaert
Publikováno v:
The Journal of clinical endocrinology and metabolism, 105 (3
Background: The early molecular events in human thyrocytes after 131I exposure have not yet been unravelled. Therefore, we investigated the role of TSH in the 131I-induced DNA damage response and gene expression in primary cultured human thyrocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70d6d6f7b5624c48d51f532a77e7ce4
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/305014
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/305014
Autor:
Laetitia Collet, Matteo Serra, Mattia Rediti, Frédéric Lifrange, David Venet, XiaoXiao Wang, Delphine Vincent, Ghizlane Rouas, Danai Fimereli, David Gacquer, Andrea Joaquin Garcia, Isabelle Veys, Ligia Craciun, Denis Larsimont, Miikka Vikkula, François Duhoux, Françoise Rothé, Christos Sotiriou
Publikováno v:
Cancer Research. 82:PD14-02
Introduction: Invasive lobular breast cancer (ILC) is the most frequent special type of breast cancer. Recent studies showed the impact of intratumor heterogeneity (ITH) on patient outcome. Here, we aimed to better characterize ITH in ILC using spati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fef671b3e3224b85f2e2a57816565150
https://doi.org/10.1158/1538-7445.sabcs21-pd14-02
https://doi.org/10.1158/1538-7445.sabcs21-pd14-02
Autor:
Denis Larsimont, Françoise Rothé, Vincent Detours, David N Brown, David Gacquer, Roberto Salgado, Debora Fumagalli, Danai Fimereli, Christos Sotiriou
Publikováno v:
Genes, Chromosomes and Cancer. 57:331-338
The advent of next generation sequencing technologies has boosted the interest in exploring the role of fusion genes in the development and progression of solid tumors. In breast cancer, most of the detected gene fusions seem to be "passenger" events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949098c5f311fbb6bcafff9c60a11f4a
https://doi.org/10.1002/gcc.22533
https://doi.org/10.1002/gcc.22533
Autor:
Vincent Detours, Franck Polleux, Marta Wojno, Adèle Herpoel, Devesh Kumar, Roxane Van Heurck, Pierre Vanderhaeghen, David Gacquer, Angéline Bilheu, Nelle Lambert, Ikuo K. Suzuki, Julian Cheron
Publikováno v:
Cell, 173 (6
The cerebral cortex underwent rapid expansion and increased complexity during recent hominid evolution. Gene duplications constitute a major evolutionary force, but their impact on human brain development remains unclear. Using tailored RNA sequencin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a5bfdc9e7c737575a63ca3baf79bd0
https://lirias.kuleuven.be/handle/123456789/647821
https://lirias.kuleuven.be/handle/123456789/647821
Autor:
Benoit Haerlingen, David Gacquer, X De Deken, Robert Opitz, Sabine Costagliola, Frédérick Libert, Achim Trubiroha, Anne Lefort, Pierre Gillotay, Nicoletta Giusti
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Scientific reports, 8 (1
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Scientific reports, 8 (1
The foregut endoderm gives rise to several organs including liver, pancreas, lung and thyroid with important roles in human physiology. Understanding which genes and signalling pathways regulate their development is crucial for understanding developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8b05adb1e2b57e09f4d67bfd7164a3
http://europepmc.org/articles/PMC5884836
http://europepmc.org/articles/PMC5884836
Autor:
Adam Shlien, Denis Larsimont, Martine Piccart, Marc Abramowicz, Naima Kheddoumi, David Gacquer, Debora Fumagalli, Karen Willard-Gallo, David N Brown, Christine Desmedt, Tomasz Konopka, Vincent Detours, Anne Lefort, Kornelia Polyak, Frédérick Libert, Françoise Rothé, Christos Sotiriou, Peter J. Campbell, Roberto Salgado
Publikováno v:
Cell Reports, Vol 13, Iss 2, Pp 277-289 (2015)
Cell Reports
Cell reports
Cell Reports
Cell reports
Summary Little is known about how RNA editing operates in cancer. Transcriptome analysis of 68 normal and cancerous breast tissues revealed that the editing enzyme ADAR acts uniformly, on the same loci, across tissues. In controlled ADAR expression e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc9d9fcd39d5adbd112f2d83a10ca57
http://www.sciencedirect.com/science/article/pii/S2211124715010438
http://www.sciencedirect.com/science/article/pii/S2211124715010438
Autor:
Carine Maenhaut, Maxime Tarabichi, Christophe Trésallet, Gil Tomás, Frédérique Savagner, David Gacquer, Tomasz Konopka, Vincent Detours, Danai Fimereli, Guy Andry, Myriam Decaussin-Petrucci, Soazig Le Pennec, Denis Larsimont
Publikováno v:
Endocrine-Related Cancer. 22:205-216
The contribution of intratumor heterogeneity to thyroid metastatic cancers is still unknown. The clonal relationships between the primary thyroid tumors and lymph nodes (LN) or distant metastases are also poorly understood. The objective of this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7cff3abe75b83317ea1c4cf4749a8db
https://doi.org/10.1530/erc-14-0351
https://doi.org/10.1530/erc-14-0351