Zobrazeno 1 - 10
of 94
pro vyhledávání: '"David GARRICK"'
Autor:
Kutaiba Alhaj Hussen, Emna Chabaane, Elisabeth Nelson, Shalva Lekiashvili, Samuel Diop, Seydou Keita, Bertrand Evrard, Aurélie Lardenois, Marc Delord, Els Verhoeyen, Kerstin Cornils, Zeinab Kasraian, Elizabeth A. Macintyre, Ana Cumano, David Garrick, Michele Goodhardt, Guillaume P. Andrieu, Vahid Asnafi, Frederic Chalmel, Bruno Canque
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107890- (2023)
Summary: The developmental cartography of human lymphopoiesis remains incompletely understood. Here, we establish a multimodal map demonstrating that lymphoid specification follows independent direct or stepwise hierarchic routes converging toward th
Externí odkaz:
https://doaj.org/article/06171025b16245b4bbab3a99462d5ce3
Autor:
Seydou Keita, Samuel Diop, Shalva Lekiashvili, Emna Chabaane, Elisabeth Nelson, Marion Strullu, Chloé Arfeuille, Fabien Guimiot, Thomas Domet, Sophie Duchez, Bertrand Evrard, Thomas Darde, Jerome Larghero, Els Verhoeyen, Ana Cumano, Elizabeth A. Macintyre, Zeinab Kasraian, François Jouen, Michele Goodhardt, David Garrick, Frederic Chalmel, Kutaiba Alhaj Hussen, Bruno Canque
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112618- (2023)
Summary: Changes in lymphocyte production patterns occurring across human ontogeny remain poorly defined. In this study, we demonstrate that human lymphopoiesis is supported by three waves of embryonic, fetal, and postnatal multi-lymphoid progenitors
Externí odkaz:
https://doaj.org/article/159f2d831f9a402db5b8c2adc8fa3349
Autor:
Audrey Abecassis, Nathalie Roders, Maxime Fayon, Caroline Choisy, Elisabeth Nelson, Stephanie Harel, Bruno Royer, Camille Villesuzanne, Alexis Talbot, David Garrick, Michele Goodhardt, Jean‐Paul Fermand, Mike Burbridge, Bertrand Arnulf, Jean‐Christophe Bories
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 970-974 (2022)
Abstract Chimeric antigen receptor T cells (CAR‐T) have provided promising results in multiple myeloma (MM). However, many patients still relapse, pointing toward the need of improving this therapy. Here, we analyzed peripheral blood T cells from M
Externí odkaz:
https://doaj.org/article/338bcbe39cad4692acdfb83db0d67b2b
Autor:
Louie N. van de Lagemaat, Maria Flenley, Magnus D. Lynch, David Garrick, Simon R. Tomlinson, Kamil R. Kranc, Douglas Vernimmen
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-18 (2018)
Abstract Background The mechanism by which protein complexes interact to regulate the deposition of post-translational modifications of histones remains poorly understood. This is particularly important at regulatory regions, such as CpG islands (CGI
Externí odkaz:
https://doaj.org/article/35a4722afad1463599673d8a85287c6a
Autor:
Dounia Djeghloul, Klaudia Kuranda, Isabelle Kuzniak, Daniela Barbieri, Irina Naguibneva, Caroline Choisy, Jean-Christophe Bories, Christine Dosquet, Marika Pla, Valérie Vanneaux, Gérard Socié, Françoise Porteu, David Garrick, Michele Goodhardt
Publikováno v:
Stem Cell Reports, Vol 6, Iss 6, Pp 970-984 (2016)
Summary: The capacity of hematopoietic stem cells (HSC) to generate B lymphocytes declines with age, contributing to impaired immune function in the elderly. Here we show that the histone methyltransferase SUV39H1 plays an important role in human B l
Externí odkaz:
https://doaj.org/article/2bfd3069f5604216847aab88774cdd80
Autor:
David Garrick, Jackie A Sharpe, Ruth Arkell, Lorraine Dobbie, Andrew J H Smith, William G Wood, Douglas R Higgs, Richard J Gibbons
Publikováno v:
PLoS Genetics, Vol 2, Iss 4, p e58 (2006)
ATRX is an X-encoded member of the SNF2 family of ATPase/helicase proteins thought to regulate gene expression by modifying chromatin at target loci. Mutations in ATRX provided the first example of a human genetic disease associated with defects in s
Externí odkaz:
https://doaj.org/article/cc53af1d8839453cb64656e6be6797c5
Autor:
Nathalie Roders, Cecilia Nakid-Cordero, Fabio Raineri, Maxime Fayon, Audrey Abecassis, Caroline Choisy, Elisabeth Nelson, Claire Maillard, David GARRICK, Alexis Talbot, Jean-Paul Fermand, Bertrand Arnulf, JEAN-CHRISTOPHE BORIES
Chimeric antigen receptor T-cell (CAR-T) therapy for multiple myeloma (MM) targeting B-cell maturation antigen (BCMA) induces high overall response rates. However, relapse still occurs and novel strategies for targeting MM cells by CAR-T are needed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e957aef2600c52fb7ef6f5dd5c9ef7ae
https://doi.org/10.21203/rs.3.rs-2687786/v1
https://doi.org/10.21203/rs.3.rs-2687786/v1
Autor:
Seydou Keita, Samuel Diop, Shalva Lekiashvili, Emna Chabaane, Elisabeth Nelson, Marion Strullu, Chloé Arfeuille, Fabien Guimiot, Thomas Domet, Sophie Duchez, Bertrand Evrard, Thomas Darde, Jerome Larghero, Els Verhoeyen, Ana Cumano, Elizabeth A. Macintyre, François Jouen, Michele Goodhardt, David Garrick, Frederic Chalmel, Kutaiba Alhaj Hussen, Bruno Canque
SUMMARYChanges in lymphocyte production patterns occurring across human ontogeny remain poorly defined. In this study, we demonstrate that human lymphopoiesis is supported by three waves of embryonic, fetal, and postnatal multi-lymphoid progenitors (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00d647b6d406dc3d4604b2ae0b816e68
https://doi.org/10.1101/2022.12.12.520060
https://doi.org/10.1101/2022.12.12.520060
Autor:
Kutaiba Alhaj Hussen, Emna Chabaane, Elisabeth Nelson, Shalva Lekiashvili, Samuel Diop, Seydou Keita, Bertrand Evrard, Aurélie Lardenois, Marc Delord, Els Verhoeyen, Kerstin Cornils, Zeinab Kasraian, Elizabeth A. Macintyre, Ana Cumano, David Garrick, Michele Goodhardt, Guillaume P. Andrieu, Vahid Asnafi, Frederic Chalmel, Bruno Canque
SUMMARYThe developmental cartography of human lymphopoiesis remains incompletely understood. Here, we establish a multimodal map that extends the current view of lymphoid development. Our results demonstrate that lymphoid specification follows indepe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d26727dd33abaa4c4d2f79334bb64197
https://doi.org/10.1101/2022.12.12.520022
https://doi.org/10.1101/2022.12.12.520022
Autor:
David Garrick, Michele Goodhardt
Publikováno v:
Hématologie. 27:242-252
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0062b767b86733eebd96e8eac09b7ce4
https://doi.org/10.1684/hma.2021.1685
https://doi.org/10.1684/hma.2021.1685