Zobrazeno 1 - 10
of 13
pro vyhledávání: '"David G. Waters"'
Autor:
Rodney Decker, Ronald B. DeMattos, Eugene Y Zhen, Li Li, Mosun Ayan-Oshodi, Ann Marie Hake, Peng Liu, David G. Waters, Brian A. Willis
Publikováno v:
Journal of Alzheimer's disease : JAD. 68(1)
LY2599666 is a humanized, affinity-optimized monoclonal antibody antigen-binding fragment linked to a PEG molecule and targets soluble amyloid-β (Aβ) monomers. This first-in-human dose ascending study assessed pharmacokinetics (PK) (measured as ser
Autor:
Bharvin K. R. Patel, Valerie Andre, Paul C Francis, David G. Waters, Sophie Callies, Michael Burgess, Michael Lahn
Publikováno v:
British Journal of Clinical Pharmacology. 71:416-428
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • The plasma pharmacokinetics (PK) of second generation antisense oligonucleotides (ASOs) are fairly well understood with well conserved pharmacokinetic properties across species, moderate clearance and exte
Autor:
Thomas Marbury, Jolene Kay Berg, Brian S. Decker, Sophie Callies, Matthew J. Sheetz, David G. Waters, Philip Barrington, Paul Berg, Donna Pappas
Publikováno v:
Blood. 128:1280-1280
Introduction: The iron transporter ferroportin is a membrane protein expressed in enterocytes that absorb dietary iron, macrophages of the spleen and liver that recycle iron from old red blood cells (RBCs), and hepatocytes that store and release iron
Publikováno v:
Journal of Pharmaceutical Sciences. 86:768-773
Glucagon-like insulinotropic peptide (GLP-1) and its analogs are of interest because of their therapeutic potential in type II diabetes. LY315902 is a GLP-1-(7–37)-OH analog with a modified N-terminus (IP7), an octanoic acid (C8) acylated on the ly
Publikováno v:
Journal of Chromatography A. 712:365-371
This paper presents the synthesis of some novel chiral surfactants based on (R,R)-tartaric acid and long-chain aliphatic amines. Evidence for their ability to form micelles based on surface tension measurements will be given. Several chiral separatio
Publikováno v:
Journal of Microcolumn Separations. 7:513-520
This article describes the synthesis of a novel chiral surfactant based on (R,R)-tartaric acid. (R,R)-Tartaric acid is acetylated while simultaneously forming a cyclic anhydride, which is then reacted with n-decylamine forming a chiral, long chain ca
Publikováno v:
Alzheimer's & Dementia. 2
Autor:
David G. Waters, Ian D. Smith
Publikováno v:
Journal of chromatography. 596(2)
This paper presents a method to identify and determine topanol A and topanol O antioxidants in methylmethacrylate and 11-bromoundecylmethacrylate. The method is both simple and rapid. Analysis is performed on a 10 m x 0.53 mm I.D. HP-1 capillary gas
Autor:
Ian D. Smith, David G. Waters
Publikováno v:
Journal of High Resolution Chromatography. 15:696-697
Autor:
Chris J. Goodwin, K. D. Altria, S. D. Filbey, A. Scott, P. R. Vojvodic, N. H. Anderson, B. J. Clark, Alison E. Bretnall, Thomas Cowen, Rachel Howling, George Hutchinson, K. M. Sereda, T. C. Hardman, M. R. Dilloway, A. F. Lant, Ian D. Smith, Paul D. Blackler, David G. Waters
Publikováno v:
Analytical Proceedings. 30:361