Zobrazeno 1 - 9
of 9
pro vyhledávání: '"David G. Twigg"'
Autor:
Tze Han Sum, Tze Jing Sum, Warren R. J. D. Galloway, Súil Collins, David G. Twigg, Florian Hollfelder, David R. Spring
Publikováno v:
Molecules, Vol 21, Iss 9, p 1230 (2016)
Flavonoids are a large family of compounds associated with a broad range of biologically useful properties. In recent years, synthetic compounds that contain two flavonoid units linked together have attracted attention in drug discovery and developme
Externí odkaz:
https://doaj.org/article/684e9beba67746929b222fe32973dd5a
Publikováno v:
Journal of Medicinal Chemistry. 65:7476-7488
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dba539a02fb3494e0c41dd1f77740e12
https://doi.org/10.1021/acs.jmedchem.2c00164
https://doi.org/10.1021/acs.jmedchem.2c00164
Autor:
David G. Twigg, Tze Jing Sum, Warren R. J. D. Galloway, Tze Han Sum, Joe J. Ciardiello, David R. Spring
Publikováno v:
Tetrahedron. 74:5089-5101
Synthetic biflavonoids are associated with interesting biological activities, yet they remain poorly explored within drug discovery. Recent years have witnessed a growing interest in synthetic approaches that can provide access to structurally novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f22cfeeb4e98de9ef68316ac8c313a48
https://doi.org/10.1016/j.tet.2018.05.003
https://doi.org/10.1016/j.tet.2018.05.003
Autor:
David G. Twigg, Noriyasu Kondo, Sophie L. Mitchell, Warren R. J. D. Galloway, Hannah F. Sore, Andrew Madin, David R. Spring
Publikováno v:
Angewandte Chemie. 128:12667-12671
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8c22138df156418f740b3734dcb6195
https://doi.org/10.1002/ange.201606496
https://doi.org/10.1002/ange.201606496
Autor:
Warren R. J. D. Galloway, Leonardo Baldassarre, David R. Spring, David G. Twigg, Elizabeth C. Frye
Publikováno v:
Organic letters. 20(6)
The first total synthesis of bussealin E, a natural product with a unique cycloheptadibenzofuran scaffold, is reported. A strategy inspired by a proposed biosynthesis was employed whereby a diphenylpropane derivative underwent an oxidative phenolic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358064bb41d57951ada729cb505f0d7e
https://pubmed.ncbi.nlm.nih.gov/29498280
https://pubmed.ncbi.nlm.nih.gov/29498280
Publikováno v:
Journal of natural products. 80(10)
Operationally simple, stereocontrolled semisyntheses of the anticancer rotenoids elliptone and 12aβ-hydroxyelliptone, isolated from Derris elliptica and Derris trifoliata, respectively, are described. Inspired by the work of Singhal, elliptone was p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8041fe7902012f635bcfe86b03c10a
https://pubmed.ncbi.nlm.nih.gov/29039664
https://pubmed.ncbi.nlm.nih.gov/29039664
Autor:
Elizabeth C. Frye, David G. Hulcoop, Cornelius J. O'Connor, David G. Twigg, David R. Spring, Luca Laraia, Ashok R. Venkitaraman, Bryony L. Elbert
Publikováno v:
ChemInform. 43
The title Hiyama reaction is performed with allylic chlorides and bromides, and benzylic chlorides, bromides, tosylates and mesylates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d577e819c8158effd272b259662e0f
https://doi.org/10.1002/chin.201246041
https://doi.org/10.1002/chin.201246041
Autor:
Cornelius J. O' Connor, David G. Twigg, Elizabeth C. Frye, Luca Laraia, David R. Spring, David G. Hulcoop, Ashok R. Venkitaraman, Bryony Elbert
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 18(28)
The Hiyama cross-coupling reaction is a powerful method for carbon-carbon bond formation. To date, the substrate scope of this reaction has predominantly been limited to sp(2)-sp(2) coupling reactions. Herein, the palladium-catalysed Hiyama type cros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8604774e41e01a1c738ee1b6c5c413a9
https://pubmed.ncbi.nlm.nih.gov/22678946
https://pubmed.ncbi.nlm.nih.gov/22678946
Autor:
David G. Twigg, Warren R. J. D. Galloway, Tze Jing Sum, Florian Hollfelder, Súil Collins, Tze Han Sum, David R. Spring
Publikováno v:
Organic & Biomolecular Chemistry
Biflavonoids are associated with a variety of biologically useful properties. However, synthetic biflavonoids are poorly explored within drug discovery. There is considerable structural diversity possible within this compound class and large regions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7adca147278ccc7fd5e6f6e81c3fb87a