Zobrazeno 1 - 9
of 9
pro vyhledávání: '"David G. Ryan"'
Publikováno v:
The Journal of Physiology. 592:1457-1477
Postsynaptic kainate receptors mediate excitatory synaptic transmission over a broad range of temporal frequencies. In heterologous systems, the temporal responses of kainate receptors vary when different channel-forming and auxiliary subunits are co
Autor:
Robert M. Lavker, Anees Fatima, Spiro Getsios, Jia Yu, David G. Ryan, Michelle Oliveira-Fernandes
Publikováno v:
Proceedings of the National Academy of Sciences. 105:19300-19305
Despite their potential to regulate approximately one-third of the whole genome, relatively few microRNA (miRNA) targets have been experimentally validated, particularly in stratified squamous epithelia. Here we demonstrate not only that the lipid ph
Publikováno v:
Journal of Biological Chemistry. 272:21151-21159
We have identified two distinct cDNAs encoding the alpha-subunit of pig heart succinyl-CoA synthetase. The derived amino acid sequence of one of these, PHalpha57, is highly similar to the alpha-subunit of the rat liver precursor enzyme. The second cD
Autor:
David G. Ryan, William A. Bridger
Publikováno v:
Journal of Molecular Biology. 219:165-174
This study comprises a detailed evaluation of factors that are necessary to achieve high levels of expression of eukaryotic proteins in bacterial systems. We attempted to express a rat liver cDNA clone encoding the precursor to the α-subunit of succ
Publikováno v:
Molecular vision. 12
In mammals, endogenous, noncoding RNAs, designated as microRNAs (miRNAs), inhibit the translation of a target messenger RNA, thereby silencing protein production. MiRNAs have been shown to regulate many aspects of development and differentiation in a
Publikováno v:
The Journal of biological chemistry. 281(16)
Two isoforms of succinyl-CoA synthetase exist in mammals, one specific for ATP and the other for GTP. The GTP-specific form of pig succinyl-CoA synthetase has been crystallized in the presence of GTP and the structure determined to 2.1 A resolution.
Publikováno v:
Journal of cellular physiology. 206(1)
Using suppressive subtractive hybridization, we have identified a novel gene, which we named early epithelial differentiation associated (EEDA), which is uniquely associated with an early stage of stratified epithelial differentiation. In epidermis,
Publikováno v:
Investigative ophthalmologyvisual science. 44(10)
PURPOSE S100A4 is a member of the S100 family of calcium-binding proteins. Members of the S100 family have been implicated in a variety of cellular events, including growth, signaling, differentiation, and motility. It has been suggested that S100A4
Publikováno v:
Biochemistry. 41(2)
Succinyl-CoA synthetase catalyzes the reversible reaction succinyl-CoA + NDP + P(i)--succinate + CoA + NTP (N denoting adenosine or guanosine). The enzyme consists of two different subunits, designated alpha and beta. During the reaction, a histidine