Zobrazeno 1 - 10
of 509
pro vyhledávání: '"David G. McLeod"'
Autor:
Nischal Mahaveer Chand, Poornima K. Tekumalla, Matt T. Rosenberg, Albert Dobi, Amina Ali, Gregory M. Miller, Juan J. Aristizabal-Henao, Elder Granger, Stephen J. Freedland, Mark D. Kellogg, Shiv Srivastava, David G. McLeod, Niven R. Narain, Michael A. Kiebish
Publikováno v:
Cancers, Vol 16, Iss 4, p 712 (2024)
Prostate cancer represents a significant health risk to aging men, in which diagnostic challenges to the identification of aggressive cancers remain unmet. Prostate cancer screening is driven by the prostate-specific antigen (PSA); however, in men wi
Externí odkaz:
https://doaj.org/article/56e0d2224a37444f8776295d07e24c09
Autor:
William Gesztes, Cara Schafer, Denise Young, Jesse Fox, Jiji Jiang, Yongmei Chen, Huai-Ching Kuo, Kuwong B. Mwamukonda, Albert Dobi, Allen P. Burke, Judd W. Moul, David G. McLeod, Inger L. Rosner, Gyorgy Petrovics, Shyh-Han Tan, Jennifer Cullen, Shiv Srivastava, Isabell A. Sesterhenn
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract TP53 is one of the most frequently altered genes in prostate cancer. The precise assessment of its focal alterations in primary tumors by immunohistochemistry (IHC) has significantly enhanced its prognosis. p53 protein expression and lymphov
Externí odkaz:
https://doaj.org/article/6313f7adee48463cb7f343d5f4ced469
Autor:
Michael A. Kiebish, Poornima Tekumalla, Shobha Ravipaty, Albert Dobi, Shiv Srivastava, Wenfang Wu, Saurabh Patil, Tracey Friss, Allison Klotz, Alagarsamy Srinivasan, Jennifer Cullen, Inger L. Rosner, Amina Ali, Sandra Laszlo, Michele Petrovic, Neil Fleshner, Jeonifer Garren, Greg Miller, Nischal Mahaveer Chand, Leonardo O. Rodrigues, Elder Granger, Mark D. Kellogg, Shen Luan, Eleftherios Diamandis, Viatcheslav R. Akmaev, Rangaprasad Sarangarajan, Chas Bountra, Stephen J. Freedland, David G. McLeod, Niven R. Narain
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Prostate-specific antigen (PSA) screening for prostate cancer (PCa) is limited by the lack of specificity but is further complicated in the benign prostatic hyperplasia (BPH) population which also exhibit elevated PSA, representing a clear u
Externí odkaz:
https://doaj.org/article/30b5d2f52b594d5593705963e0ea8e51
Autor:
Michael A. Kiebish, Jennifer Cullen, Prachi Mishra, Amina Ali, Eric Milliman, Leonardo O. Rodrigues, Emily Y. Chen, Vladimir Tolstikov, Lixia Zhang, Kiki Panagopoulos, Punit Shah, Yongmei Chen, Gyorgy Petrovics, Inger L. Rosner, Isabell A. Sesterhenn, David G. McLeod, Elder Granger, Rangaprasad Sarangarajan, Viatcheslav Akmaev, Alagarsamy Srinivasan, Shiv Srivastava, Niven R. Narain, Albert Dobi
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-10 (2020)
Abstract Background Predicting the clinical course of prostate cancer is challenging due to the wide biological spectrum of the disease. The objective of our study was to identify prostate cancer prognostic markers in patients ‘sera using a multi-o
Externí odkaz:
https://doaj.org/article/4c95a22fa38048aeaa9f5cfd28ba10df
Autor:
Shashwat Sharad, Travis C. Allemang, Hua Li, Darryl Nousome, Anson Tai Ku, Nichelle C. Whitlock, Adam G. Sowalsky, Jennifer Cullen, Isabell A. Sesterhenn, David G. McLeod, Shiv Srivastava, Albert Dobi
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Prostate cancer incidence in young men has increased. Patients diagnosed at an earlier age are likely to have aggressive prostate cancer and treatment decisions are continuing to be weighted by patient age and life expectancy. Identification of age-a
Externí odkaz:
https://doaj.org/article/590ccb1bab334107afadcbe761637168
Autor:
Gyorgy Petrovics, Hua Li, Tanja Stümpel, Shyh-Han Tan, Denise Young, Shilpa Katta, Qiyuan Li, Kai Ying, Bernward Klocke, Lakshmi Ravindranath, Indu Kohaar, Yongmei Chen, Dezső Ribli, Korbinian Grote, Hua Zou, Joseph Cheng, Clifton L. Dalgard, Shimin Zhang, István Csabai, Jacob Kagan, David Takeda, Massimo Loda, Sudhir Srivastava, Matthias Scherf, Martin Seifert, Timo Gaiser, David G. McLeod, Zoltan Szallasi, Reinhard Ebner, Thomas Werner, Isabell A. Sesterhenn, Matthew Freedman, Albert Dobi, Shiv Srivastava
Publikováno v:
EBioMedicine, Vol 2, Iss 12, Pp 1957-1964 (2015)
Evaluation of cancer genomes in global context is of great interest in light of changing ethnic distribution of the world population. We focused our study on men of African ancestry because of their disproportionately higher rate of prostate cancer (
Externí odkaz:
https://doaj.org/article/cae9c00da3ed473d85e39e12725fd539
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 8, Pp 15510-15531 (2013)
Prostate cancer is the most common non-skin cancer and the second leading cause of cancer-related death for men in the United States. Prostate cancer incidence and associated mortality are highest in African American men in comparison to other races.
Externí odkaz:
https://doaj.org/article/8c9cd952d63a4bddaa0898210299b8a2
Autor:
Jennifer Cullen, Stephen A. Brassell, Yongmei Chen, Christopher Porter, James L'Esperance, Timothy Brand, David G. McLeod
Publikováno v:
Prostate Cancer, Vol 2011 (2011)
Introduction. Concern regarding overtreatment of prostate cancer (CaP) is leading to increased attention on active surveillance (AS). This study examined CaP survivors on AS and compared secondary treatment patterns and overall survival by race/ethni
Externí odkaz:
https://doaj.org/article/bcac8bb97ead44beb202a63daf004144
Autor:
Shiv Srivastava, Albert Dobi, Gyorgy Petrovics, Alagarsamy Srinivasan, David G. McLeod, Taduru L. Sreenath, Eri S. Srivatsan, Meera Srivastava, Hua Li, Muhammad Jamal, Lakshmi Ravindranath, Wei Huang, Shilpa Katta, Charles P. Xavier, Shyh-Han Tan, Ahmed A. Mohamed
ERG binding sites on NOTCH1 and NOTCH2 promoters and primer sequences used to amplify these locations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cb6bc9b0765dd254924ae5b34c3e2b
https://doi.org/10.1158/1541-7786.22515540.v1
https://doi.org/10.1158/1541-7786.22515540.v1
Autor:
Shiv Srivastava, Albert Dobi, Gyorgy Petrovics, Alagarsamy Srinivasan, David G. McLeod, Taduru L. Sreenath, Eri S. Srivatsan, Meera Srivastava, Hua Li, Muhammad Jamal, Lakshmi Ravindranath, Wei Huang, Shilpa Katta, Charles P. Xavier, Shyh-Han Tan, Ahmed A. Mohamed
The oncogenic activation of the ETS-related gene (ERG) due to gene fusions is present in over half of prostate cancers in Western countries. Because of its high incidence and oncogenic role, ERG and components of ERG network have emerged as potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cae8bee2ba090953d25bd0253cdc4f9f
https://doi.org/10.1158/1541-7786.c.6541119
https://doi.org/10.1158/1541-7786.c.6541119