Zobrazeno 1 - 10
of 88
pro vyhledávání: '"David G. Klapper"'
Autor:
Brittany C. Williams, David G. Klapper, Amanda L. Russell, Rickey P. Hicks, Antoine H. Srouji, Anne M. Spuches
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:1723-1739
The intent of this investigation was to determine the effect of varying the side chain length of the basic amino acids residues on the binding of a series of antimicrobial peptides (AMPs) to zwitterionic and anionic LUVs, SUVs and micelles. These AMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5122c6f9ff6494c11584ab11a103e054
https://doi.org/10.1016/j.bmc.2012.01.015
https://doi.org/10.1016/j.bmc.2012.01.015
Autor:
Divakaramenon Venugopal, Anthony Kennedy, Jayendra B. Bhonsle, Antoine H. Srouji, David G. Klapper, Rickey P. Hicks, Amanda L. Russell, William S. Gibson, Anne M. Spuches
Publikováno v:
Chemistry and Physics of Lipids. 164:740-758
Circular Dichroism (CD), isothermal calorimetry (ITC) and calcein fluorescence leakage experiments were conducted to provide insight into the mechanisms of binding of a series of antimicrobial peptides containing unnatural amino acids (Ac-XF-Tic-Oic-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13895a17cce247baa825eb031d17fbc4
https://doi.org/10.1016/j.chemphyslip.2011.09.003
https://doi.org/10.1016/j.chemphyslip.2011.09.003
Publikováno v:
Molecular Microbiology. 82:9-20
Polyamines, including spermine (Spm) and spermidine (Spd), are aliphatic cations that are reportedly synthesized by all living organisms. They exert pleiotropic effects on cells and are required for efficient nucleic acid and protein synthesis. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ced19795d40da9a1631d41d481a50c2
https://doi.org/10.1111/j.1365-2958.2011.07809.x
https://doi.org/10.1111/j.1365-2958.2011.07809.x
Autor:
Rickey P. Hicks, Brittany C. Williams, Allen J. Mueller, Antoine H. Srouji, Jayendra B. Bhonsle, David G. Klapper, Divakaramenon Venugopal, Richard Borschel, Amanda L. Russell
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:5137-5147
One of the greatest challenges facing modern medicine is the evolution of drug resistant strains of bacteria. In addition to traditional methods of exposure to traditional bacterial organisms there is a growing concerned of the use of bacteria as bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20df4bd9a731c3ecfaabb85a0c3bf7cf
https://doi.org/10.1016/j.bmc.2010.05.065
https://doi.org/10.1016/j.bmc.2010.05.065
Publikováno v:
Hybridoma. 28:189-197
An IgM monoclonal antibody, S11-23.4, raised against the 47-62 amino acid sequence in bovine prothrombin fragment 1 (F-1, the amino-terminal 156 residues of prothrombin), was purified from tissue culture supernatants and ascites using different purif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108d8a18c67d54d93d3c6cce9111e795
https://doi.org/10.1089/hyb.2008.0087
https://doi.org/10.1089/hyb.2008.0087
Publikováno v:
Human Antibodies. 17:85-96
Bovine prothrombin fragment 1 (F-1: the amino-terminal 156 residues of prothrombin) is used as a model to study the Ca(II) and phospholipid binding of prothrombin. The 35-46 segment in F-1 posses an α-helical region and three aromatic residues, cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d5c3e6e663f2c2536c8d46e843c169
https://doi.org/10.3233/hab-2008-173-406
https://doi.org/10.3233/hab-2008-173-406
Autor:
Leena A. Nylander-French, Tae-gyu Nam, Juei Chuan C. Kang-Sickel, John E. French, Donii D. Fox, Avram Gold, Louise M. Ball, David G. Klapper, K. Jayaraj
Publikováno v:
Chemical Research in Toxicology. 21:852-858
To measure biomarkers of skin exposure to ubiquitous industrial and environmental aromatic hydrocarbons, we sought to develop an ELISA to quantitate protein adducts of metabolites of benzene and naphthalene in the skin of exposed individuals. We hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493d102ff9454853c6aa5248c8566450
https://doi.org/10.1021/tx7003773
https://doi.org/10.1021/tx7003773
Publikováno v:
Pharmaceutical Research. 22:122-127
To understand the structural requirements in designing epitope-bearing oligonucleotides with high antibody-binding affinity.Binding affinity (KA) and stoichiometry (n) of dinitrophenyl (DNP)-derivatized model 27-mer oligonucleotides (ODNs), GGG(AAA)7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78262412ff0acac7aab1fdcad71a47d
https://doi.org/10.1007/s11095-004-9017-z
https://doi.org/10.1007/s11095-004-9017-z
Autor:
K. Jayaraj, Leena A. Nylander-French, David G. Klapper, Tae-gyu Nam, Avram Gold, Ramiah Sangaiah, Louise M. Ball, John E. French
Publikováno v:
Organic Preparations and Procedures International. 35:375-382
(2003). SYNTHESIS OF S-ARYL-D,L-CYSTEINES AND INCORPORATION INTO KERATIN SEQUENCES. Organic Preparations and Procedures International: Vol. 35, No. 4, pp. 375-382.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23aa9a9b394d7e72e3f35bead9c1fbc8
https://doi.org/10.1080/00304940309355843
https://doi.org/10.1080/00304940309355843
Viral fusion peptides are short N-terminal regions of type-1 viral fusion proteins that are critical for virus entry. Although the importance of viral fusion peptides in virus-cell membrane fusion is established, little is known about how they functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d25f96fd9ef8d20242cfa1989da6979
