Zobrazeno 1 - 10
of 27
pro vyhledávání: '"David G. Hancock"'
Autor:
Elizabeth Kicic-Starcevich, David G. Hancock, Thomas Iosifidis, Patricia Agudelo-Romero, Jose A. Caparros-Martin, Yuliya V. Karpievitch, Desiree Silva, Lidija Turkovic, Peter N. Le Souef, Anthony Bosco, David J. Martino, Anthony Kicic, Susan L. Prescott, Stephen M. Stick
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
IntroductionRecurrent wheezing disorders including asthma are complex and heterogeneous diseases that affect up to 30% of all children, contributing to a major burden on children, their families, and global healthcare systems. It is now recognized th
Externí odkaz:
https://doaj.org/article/63c7867954a64ed681c2a2469b6882d0
Autor:
David G. Hancock, William Ditcham, Eleanor Ferguson, Yuliya V. Karpievitch, Stephen M. Stick, Grant W. Waterer, Barry S. Clements
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundCurrent treatments for respiratory infections are severely limited. Ethanol’s unique properties including antimicrobial, immunomodulatory, and surfactant-like activity make it a promising candidate treatment for respiratory infections if
Externí odkaz:
https://doaj.org/article/c51e8bdc15cf4f109ca1055ab2a86f0b
Autor:
José A. Castro-Rodriguez, Eleanor N. Fish, Samuel T. Montgomery, Tobias R. Kollmann, Carolina Iturriaga, Casey Shannon, Yuliya Karpievitch, Joseph Ho, Virginia Chen, Robert Balshaw, Rym Ben-Othman, Radhouane Aniba, Francisca Gidi-Yunge, Lucy Hartnell, David G. Hancock, Guillermo Pérez-Mateluna, Marcela Urzúa, Scott J. Tebbutt, Diego García-Huidobro, Cecilia Perret, Arturo Borzutzky, Stephen M. Stick
Publikováno v:
EClinicalMedicine, Vol 62, Iss , Pp 102082- (2023)
Summary: Background: Accumulating evidence indicates that an early, robust type 1 interferon (IFN) response to SARS-CoV-2 is important in determining COVID-19 outcomes, with an inadequate IFN response associated with disease severity. Our objective w
Externí odkaz:
https://doaj.org/article/d8d8e7c67f0844a18d712d629bff8ce5
Autor:
Olga M. Pena, David G. Hancock, Ngan H. Lyle, Adam Linder, James A. Russell, Jianguo Xia, Christopher D. Fjell, John H. Boyd, Robert E.W. Hancock
Publikováno v:
EBioMedicine, Vol 1, Iss 1, Pp 64-71 (2014)
Background: Sepsis involves aberrant immune responses to infection, but the exact nature of this immune dysfunction remains poorly defined. Bacterial endotoxins like lipopolysaccharide (LPS) are potent inducers of inflammation, which has been associa
Externí odkaz:
https://doaj.org/article/1c734797dbc24577918cab5ecd96cdb8
Publikováno v:
JBI Evidence Synthesis. 20:60-120
The objective of this review was to investigate the available qualitative evidence to enhance understanding of the experiences of children and young adults living with juvenile idiopathic arthritis, and their carers, in any setting.Juvenile idiopathi
Autor:
Nathaniel Schrein, Darren Campbell, Choo Keong Ong, Bradley Gardner, Justin Lightner, David G. Hancock
Publikováno v:
Electrical Transmission and Substation Structures 2022.
Autor:
David G Hancock, Elena Shklovskaya, Thomas V Guy, Reza Falsafi, Chris D Fjell, William Ritchie, Robert E W Hancock, Barbara Fazekas de St Groth
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100613 (2014)
Dendritic cells (DCs) are critical for regulating CD4 and CD8 T cell immunity, controlling Th1, Th2, and Th17 commitment, generating inducible Tregs, and mediating tolerance. It is believed that distinct DC subsets have evolved to control these diffe
Externí odkaz:
https://doaj.org/article/117bf5d8a4c744028ff45d77176fdb29
Publikováno v:
JBI evidence synthesis. 18(9)
OBJECTIVE The objective of this review was to investigate the available qualitative evidence to enhance understanding of the experiences of children, young adults, and their carers living with Juvenile Idiopathic Arthritis in any setting. INTRODUCTIO
Autor:
Rachel Jones, Matthew Horsfall, William A. Parsonage, Derek P. Chew, Rebecca Bystrom, Ming Yu Anthony Chuang, Louise Cullen, Amera Halabi, David G. Hancock
Publikováno v:
Emergency Medicine Australasia. 29:664-671
Objective Many meta-analyses have provided synthesised likelihood ratio data to aid clinical decision-making. However, much less has been published on how to safely combine clinical information in practice. We aimed to explore the benefits and risks
Autor:
Holly A. Bolton, Elena Shklovskaya, Barbara Fazekas de St Groth, David G. Hancock, Thomas V. Guy, Alexandra M. Terry
Publikováno v:
Cancer Immunology, Immunotherapy. 65:885-896
The primary immune role of B cells is to produce antibodies, but they can also influence T cell function via antigen presentation and, in some contexts, immune regulation. Whether their roles in tumour immunity are similar to those in other chronic i