Zobrazeno 1 - 5
of 5
pro vyhledávání: '"David G. Donne"'
Autor:
David G. Gorenstein, Varatharasa Thiviyanathan, David G. Donne, Bruce A. Luxon, Nishantha Illangasekare, Neocles B. Leontis
Publikováno v:
Journal of Biomolecular NMR. 14:209-221
Homonuclear 3D NOESY-NOESY has shown great promise for the structural refinement of large biomolecules. A computationally efficient hybrid-hybrid relaxation matrix refinement methodology, using 3D NOESY-NOESY data, was used to refine the structure of
Autor:
Ingrid Mehlhorn, David G. Donne, He Liu, Shauna Farr-Jones, Fred E. Cohen, Kiyotoshi Kaneko, Nikolai B. Ulyanov, Hong Zhang, Thomas L. James, Darlene Groth, Stanley B. Prusiner
Publikováno v:
Proceedings of the National Academy of Sciences. 94:10086-10091
The scrapie prion protein (PrP Sc ) is the major, and possibly the only, component of the infectious prion; it is generated from the cellular isoform (PrP C ) by a conformational change. N-terminal truncation of PrP Sc by limited proteolysis produces
Autor:
David G. Gorenstein, David G. Donne
Publikováno v:
Concepts in Magnetic Resonance. 9:95-111
A complete pictorial representation for the product operator formalism has been developed to describe arbitrary multidimensional and multinuclear NMR experiments. A complete set of 16 multiple-headed vectors has been derived for a weakly coupled, two
Publikováno v:
Magnetic Resonance in Chemistry. 34:S125-S135
A hybrid-hybrid relaxation rate matrix refinement of 3D NOESY-NOESY data was tested by simulated refinement calculations on a dodecamer duplex DNA structure. 'Experimental' 3D data sets were generated from the known target structure for the simulated
Autor:
Darlene Groth, Peter E. Wright, John H. Viles, Ingrid Mehlhorn, Thomas L. James, Stanley B. Prusiner, H.J. Dyson, Fred E. Cohen, David G. Donne
The prion diseases seem to be caused by a conformational change of the prion protein (PrP) from the benign cellular form PrP C to the infectious scrapie form PrP Sc ; thus, detailed information about PrP structure may provide essential insights into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a02076d5c495a3eefa1a22889877d24
https://europepmc.org/articles/PMC28326/
https://europepmc.org/articles/PMC28326/