Zobrazeno 1 - 10
of 76
pro vyhledávání: '"David G. C. Owens"'
Autor:
Louise Robinson, Michael D Spencer, Lindsay D G Thomson, Andrew C Stanfield, David G C Owens, Jeremy Hall, Eve C Johnstone
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36078 (2012)
UNLABELLED: There have been concerns that individuals with autism spectrum disorders (ASDs) are over-represented but not recognised in prison populations. A screening tool for ASDs in prisons has therefore been developed. AIMS: We aimed to evaluate t
Externí odkaz:
https://doaj.org/article/80d89fd44a8c4d419b58313405ae2d37
Autor:
David G. C. Owens
Publikováno v:
British Journal of Psychiatry. 215:516-518
SummarySodium valproate and related preparations have recently undergone regulatory review following concern about effects on the unborn child and doctors' failure to communicate risk. The issues are wider. Valproate is overused in psychiatry based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4339c4da85230a3e0478606e3447c153
https://doi.org/10.1192/bjp.2019.137
https://doi.org/10.1192/bjp.2019.137
Autor:
Eve C. Johnstone, Stephen M. Lawrie, David G. C. Owens, Andrew McKechanie, Andrew C. Stanfield
Publikováno v:
The British journal of psychiatry : the journal of mental science. 215(1)
BackgroundPsychotic symptoms and psychotic disorders occur at increased rates in adults with intellectual disability, including borderline intellectual functioning, compared with the general population. Little is known about the development of such s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1685f66d4d43f1009b914f6ede3f59
https://pubmed.ncbi.nlm.nih.gov/30693855
https://pubmed.ncbi.nlm.nih.gov/30693855
Autor:
Stephen M. Lawrie, Emma Neilson, Heather C. Whalley, Eve C. Johnstone, Catherine Bois, Andrew M. McIntosh, David G. C. Owens, Victoria Barker
Publikováno v:
Barker, V, Bois, C, Neilson, E, Johnstone, E C, Owens, D, Whalley, H, McIntosh, A & Lawrie, S 2016, ' Childhood adversity and hippocampal and amygdala volumes in a population at familial high risk of schizophrenia ', Schizophrenia Research . https://doi.org/10.1016/j.schres.2016.04.028
Background There is an established link between childhood adversity (CA) and schizophrenia. Hippocampus and amygdala abnormalities pre-date onset in those at high familial risk (fHR) of schizophrenia, but it is not clear whether these alterations are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd51e29e165567651623528771afcb97
https://doi.org/10.1016/j.schres.2016.04.028
https://doi.org/10.1016/j.schres.2016.04.028
Autor:
Andrew C. Stanfield, Stephen M. Lawrie, David G. C. Owens, Heather C. Whalley, T.W. Moorhead, Eve C. Johnstone, Andrew McKechanie
Publikováno v:
McKechanie, A, Moorhead, T W J, Stanfield, A C, Whalley, H C, Johnstone, E, Lawrie, S M & Owens, D G C 2016, ' Negative symptoms and longitudinal gray matter tissue loss in adolescents at risk of psychosis : Preliminary findings from a 6-year follow-up study. ', British Journal of Psychiatry, vol. 208, no. 6, pp. 565-570 . https://doi.org/10.1192/bjp.bp.114.154526
BackgroundNegative symptoms are perhaps the most disabling feature of schizophrenia. Their pathogenesis remains poorly understood and it has been difficult to assess their development over time with imaging techniques.AimsTo examine, using tensor-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddffb2e9f6ff1a6e6af855b82ebe134
https://doi.org/10.1192/bjp.bp.114.154526
https://doi.org/10.1192/bjp.bp.114.154526
Autor:
David G. C. Owens, Eve C. Johnstone
Publikováno v:
Brain and Neuroscience Advances
Antipsychotic drugs revolutionised psychiatric practice and provided a range of tools for exploring brain function in health and disease. Their development and introduction were largely empirical but based on long and honourable scientific credential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f504472121a16e5a506b87fa17488180
http://europepmc.org/articles/PMC7058266
http://europepmc.org/articles/PMC7058266
Autor:
Heather C. Whalley, Eve C. Johnstone, Andrew M. McIntosh, David G. C. Owens, Catherine Bois, Victoria Barker, Stephen M. Lawrie
Publikováno v:
Psychological Medicine. 46:891-896
BackgroundThere is now a well-established link between childhood adversity (CA) and schizophrenia. Similar structural abnormalities to those found in schizophrenia including alterations in grey-matter volume have also been shown in those who experien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe5e6781ddfa4ca40a021a8ca7aa380
https://doi.org/10.1017/s0033291715002585
https://doi.org/10.1017/s0033291715002585
Autor:
Lisa Hall, Emma Neilson, Catherine Bois, Eve C. Johnstone, Stephen M. Lawrie, Toni-Kim Clarke, Andrew M. McIntosh, David G. C. Owens, Heather C. Whalley
Publikováno v:
Neilson, E, Bois, C, Clarke, T-K, Hall, L, Johnstone, E C, Owens, D G C, Whalley, H C, McIntosh, A M & Lawrie, S M 2018, ' Polygenic risk for schizophrenia, transition and cortical gyrification : a high-risk study ', Psychological Medicine, vol. 48, no. 9, pp. 1532-1539 . https://doi.org/10.1017/S0033291717003087
BackgroundSchizophrenia is a highly heritable disorder, linked to several structural abnormalities of the brain. More specifically, previous findings have suggested that increased gyrification in frontal and temporal regions are implicated in the pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b832fed486651b225136a43100feb0e
https://pubmed.ncbi.nlm.nih.gov/29065934
https://pubmed.ncbi.nlm.nih.gov/29065934
Autor:
Eve C. Johnstone, Vincent Valton, Thomas W.J. Moorhead, Stephen M. Lawrie, David G. C. Owens, Heather C. Whalley, Liana Romaniuk, Maria R. Dauvermann
Publikováno v:
NeuroImage. 73:16-29
Nonlinear Dynamic Causal Modelling (DCM) for fMRI provides computational modelling of gating mechanisms at the neuronal population level. It allows for estimations of connection strengths with nonlinear modulation within task-dependent networks. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cc3ddecfec9f20d06421dae3b9a3b8
https://doi.org/10.1016/j.neuroimage.2013.01.063
https://doi.org/10.1016/j.neuroimage.2013.01.063
Publikováno v:
Zarogianni, E, Storkey, A J, Johnstone, E C, Owens, D G C & Lawrie, S M 2016, ' Improved individualized prediction of schizophrenia in subjects at familial high risk, based on neuroanatomical data, schizotypal and neurocognitive features ', Schizophrenia Research . https://doi.org/10.1016/j.schres.2016.08.027
To date, there are no reliable markers for predicting onset of schizophrenia in individuals at high risk (HR). Substantial promise is, however, shown by a variety of pattern classification approaches to neuroimaging data. Here, we examined the predic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70c49e4c20fbcba614bd9e813f408ed
https://pubmed.ncbi.nlm.nih.gov/27613509
https://pubmed.ncbi.nlm.nih.gov/27613509