Zobrazeno 1 - 10
of 51
pro vyhledávání: '"David G. Ashbrook"'
Autor:
Khyobeni Mozhui, James P. O’Callaghan, David G. Ashbrook, Pjotr Prins, Wenyuan Zhao, Lu Lu, Byron C. Jones
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Of the nearly 1 million military personnel who participated in the 1990–1991 Gulf War, between 25% and 35% became ill with what now is referred to as Gulf War Illness (GWI) by the Department of Defense. Symptoms varied from gastrointestinal distres
Externí odkaz:
https://doaj.org/article/46d99daf5f1b41e38b60dbc925700c88
Autor:
Xinfeng Wang, Akhilesh K. Bajpai, Qingqing Gu, David G. Ashbrook, Athena Starlard-Davenport, Lu Lu
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Acute myeloid leukemia (AML) is the most common type of leukemia in adults. However, there is a gap in understanding the molecular basis of the disease, partly because key genes associated with AML have not been extensively explored. In
Externí odkaz:
https://doaj.org/article/b44c2be3b68f41d2853ca18bc75b858b
Autor:
Qingqing Gu, Buyan-Ochir Orgil, Akhilesh Kumar Bajpai, Yufeng Chen, David G. Ashbrook, Athena Starlard-Davenport, Jeffrey A. Towbin, Djamel Lebeche, Enkhsaikhan Purevjav, Hongzhuan Sheng, Lu Lu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12759 (2023)
Background: Troponin-I interacting kinase encoded by the TNNI3K gene is expressed in nuclei and Z-discs of cardiomyocytes. Mutations in TNNI3K were identified in patients with cardiac conduction diseases, arrhythmias, and cardiomyopathy. Methods: We
Externí odkaz:
https://doaj.org/article/505c10670a8244e99f27e59f887a98a1
Autor:
Paula Dietrich, Shanta Alli, Megan K. Mulligan, Rachel Cox, David G. Ashbrook, Robert W. Williams, Ioannis Dragatsis
Publikováno v:
Neurobiology of Disease, Vol 162, Iss , Pp 105581- (2022)
Mitochondria dysfunction occurs in the aging brain as well as in several neurodegenerative disorders and predisposes neuronal cells to enhanced sensitivity to neurotoxins. 3-nitropropionic acid (3-NP) is a naturally occurring plant and fungal neuroto
Externí odkaz:
https://doaj.org/article/d56f2e4c0c394707995eb84a7cac2bbc
Autor:
Alexandra Noël, David G. Ashbrook, Fuyi Xu, Stephania A. Cormier, Lu Lu, James P. O’Callaghan, Shyam K. Menon, Wenyuan Zhao, Arthur L. Penn, Byron C. Jones
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12461 (2022)
Air pollution is a known environmental health hazard. A major source of air pollution includes diesel exhaust (DE). Initially, research on DE focused on respiratory morbidities; however, more recently, exposures to DE have been associated with neurol
Externí odkaz:
https://doaj.org/article/2582620027c7477fa36c8d24065a3a05
Autor:
Samantha C. Lauby, David G. Ashbrook, Hannan R. Malik, Diptendu Chatterjee, Pauline Pan, Alison S. Fleming, Patrick O. McGowan
Publikováno v:
Brain and Behavior, Vol 11, Iss 4, Pp n/a-n/a (2021)
Abstract Introduction Rat mothers exhibit natural variations in care that propagate between generations of female offspring. However, there is limited information on genetic variation that could influence this propagation. Methods We assessed early
Externí odkaz:
https://doaj.org/article/5b06931bbde74ab5b0037b6019642948
Publikováno v:
Genes, Vol 13, Iss 4, p 614 (2022)
Gene-by-environment interactions are important for all facets of biology, especially behaviour. Families of isogenic strains of mice, such as the BXD strains, are excellently placed to study these interactions, as the same genome can be tested in mul
Externí odkaz:
https://doaj.org/article/7ba3aad86abc48258a2526eded4f2641
Autor:
Fuyi Xu, Jun Gao, Silke Bergmann, Amy C. Sims, David G. Ashbrook, Ralph S. Baric, Yan Cui, Colleen B. Jonsson, Kui Li, Robert W. Williams, Klaus Schughart, Lu Lu
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Acute lung injury (ALI) is an important cause of morbidity and mortality after viral infections, including influenza A virus H1N1, SARS-CoV, MERS-CoV, and SARS-CoV-2. The angiotensin I converting enzyme 2 (ACE2) is a key host membrane-bound protein t
Externí odkaz:
https://doaj.org/article/9dc74bbdac0144dd90695b511625fcda
Autor:
Nian Wang, Robert J. Anderson, David G. Ashbrook, Vivek Gopalakrishnan, Youngser Park, Carey E. Priebe, Yi Qi, Rick Laoprasert, Joshua T. Vogelstein, Robert W. Williams, G. Allan Johnson
Publikováno v:
NeuroImage, Vol 222, Iss , Pp 117274- (2020)
Genome-wide association studies have demonstrated significant links between human brain structure and common DNA variants. Similar studies with rodents have been challenging because of smaller brain volumes. Using high field MRI (9.4 T) and compresse
Externí odkaz:
https://doaj.org/article/03ebff223e424c88a43324508638004b
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Background: Prepulse inhibition (PPI) of the startle response is a highly conserved form of sensorimotor gating, disruption of which is found in schizophrenia patients and their unaffected first-degree relatives. PPI can be measured in many species,
Externí odkaz:
https://doaj.org/article/7b5aba28fe844c1681f8cfd0417c3400