Zobrazeno 1 - 10
of 248
pro vyhledávání: '"David G. Fernig"'
Autor:
Jessica M. Rustia, Judith P. Antonino, Ravelina R. Velasco, Marcelo A. Lima, Edwin A. Yates, David G. Fernig
Publikováno v:
Fishes, Vol 8, Iss 10, p 493 (2023)
The windowpane oyster Placuna placenta lives in brackish coastal waters and has long been economically important to the Philippines because of its durable and translucent shell, which is used as a glass substitute and material for making windowpanes
Externí odkaz:
https://doaj.org/article/feeb52a00d544feaaabb69d88caef443
Publikováno v:
Open Biology, Vol 12, Iss 9 (2022)
Fibroblasts are widely distributed cells found in most tissues and upon tissue injury, they are able to differentiate into myofibroblasts, which express abundant extracellular matrix (ECM) proteins. Overexpression and unordered organization of ECM pr
Externí odkaz:
https://doaj.org/article/f2969f3ce5cd4e68839f0ad95cc1ee84
Autor:
Christopher A. W. David, M. Estela del Castillo Busto, Susana Cuello-Nuñez, Heidi Goenaga-Infante, Michael Barrow, David G. Fernig, Patricia Murray, Matthew J. Rosseinsky, Andrew Owen, Neill J. Liptrott
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Background Safe and rational development of nanomaterials for clinical translation requires the assessment of potential biocompatibility. Autophagy, a critical homeostatic pathway intrinsically linked to cellular health and inflammation, has
Externí odkaz:
https://doaj.org/article/d61717e8f0e94888a27f085b19fa15aa
Autor:
Stephen Kaye, Keri McLean, Dominic Byrne, Craig Winstanley, Daniel M Foulkes, Marta Sloniecka, Atikah S Haneef, Neil G Berry, David G Fernig
Publikováno v:
BMJ Open Ophthalmology, Vol 7, Iss Suppl 1 (2022)
Externí odkaz:
https://doaj.org/article/b5ea491a594d42a396902e0d903d5a3a
Autor:
Courtney J Mycroft-West, Anthony J Devlin, Lynsay C Cooper, Patricia Procter, Gavin J Miller, David G Fernig, Marco Guerrini, Scott E Guimond, Marcelo A Lima, Edwin A Yates, Mark Andrew Skidmore
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 8, Pp 1546-1553 (2020)
The pharmaceutical and anticoagulant agent heparin, a member of the glycosaminoglycan family of carbohydrates, has previously been identified as a potent inhibitor of a key Alzheimer’s disease drug target, the primary neuronal β-secretase, β-site
Externí odkaz:
https://doaj.org/article/d30637bf9c56424598842f9e806a405d
Autor:
Changye Sun, Mengxin Liu, Panwen Sun, Mingming Yang, Edwin A. Yates, Zhikun Guo, David G. Fernig
Publikováno v:
FEBS Open Bio, Vol 9, Iss 8, Pp 1477-1487 (2019)
Fibroblast growth factors (FGFs) regulate embryonic development and homeostasis, including tissue and organ repair and specific aspects of metabolism. The basic FGF and acidic FGF, now known as FGF2 and FGF1, are widely used protein drugs for tissue
Externí odkaz:
https://doaj.org/article/eb45c05452324b728998c57b92881765
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 1038-1047 (2019)
The influenza (“flu”) type-A virus is a major medical and veterinary health concern and causes global pandemics. The peptide “FluPep” is an established inhibitor of influenza virus infectivity in model systems. We have explored the potential
Externí odkaz:
https://doaj.org/article/2bb63c09eb904f6e96dfafab88ed836e
Autor:
Quentin M Nunes, Dunhao Su, Philip J Brownridge, Deborah M Simpson, Changye Sun, Yong Li, Thao P Bui, Xiaoying Zhang, Wei Huang, Daniel J Rigden, Robert J Beynon, Robert Sutton, David G Fernig
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217633 (2019)
Acute pancreatitis (AP) is acute inflammation of the pancreas, mainly caused by gallstones and alcohol, driven by changes in communication between cells. Heparin-binding proteins (HBPs) play a central role in health and diseases. Therefore, we used h
Externí odkaz:
https://doaj.org/article/42f521e277b448e89cb95674604e666f
Autor:
Courtney J. Mycroft-West, Anthony J. Devlin, Lynsay C. Cooper, Scott E. Guimond, Patricia Procter, Marco Guerrini, Gavin J. Miller, David G. Fernig, Edwin A. Yates, Marcelo A. Lima, Mark A. Skidmore
Publikováno v:
Marine Drugs, Vol 19, Iss 4, p 203 (2021)
Only palliative therapeutic options exist for the treatment of Alzheimer’s Disease; no new successful drug candidates have been developed in over 15 years. The widely used clinical anticoagulant heparin has been reported to exert beneficial effects
Externí odkaz:
https://doaj.org/article/9cb423e1e6474f8a8ed5966155f70135
Autor:
Simon Wheeler, Colum Breen, Yong Li, Sarah H. Hewitt, Erin Robertson, Edwin A. Yates, Igor L. Barsukov, David G. Fernig, Stephen J. Butler
Publikováno v:
Organic & Biomolecular Chemistry. 20:596-605
Sulfotransferases constitute a ubiquitous class of enzymes which are poorly understood due to the lack of a convenient tool for screening their activity. These enzymes use the anion PAPS (adenosine-3'-phosphate-5'-phosphosulfate) as a donor for a bro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c4ba002eddb606bce9281e92068bbd
https://doi.org/10.1039/d1ob02071d
https://doi.org/10.1039/d1ob02071d