Zobrazeno 1 - 10
of 18
pro vyhledávání: '"David G Nickens"'
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12368 (2010)
BACKGROUND: In vitro selection of kinase ribozymes for small molecule metabolites, such as free nucleosides, will require partition systems that discriminate active from inactive RNA species. While nucleic acid catalysis of phosphoryl transfer is wel
Externí odkaz:
https://doaj.org/article/55e3316d4b00498294adad62b383b79c
Autor:
Prasangi Rajapaksha, Robert H. Simmons, Spencer J. Gray, David J. Sun, Phoebe Nguyen, David G. Nickens, Matthew L. Bochman
Publikováno v:
Methods Enzymol
Helicase Enzymes Part B ISBN: 9780323997737
Helicase Enzymes Part B ISBN: 9780323997737
DNA helicases are involved in nearly all facets of genome integrity, and in humans, mutations in helicase-encoding genes are often linked to diseases of genomic instability. Two highly studied and evolutionarily conserved helicase families are the PI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca967304a10cb499bf5bbd19de41451
https://pubmed.ncbi.nlm.nih.gov/35965006
https://pubmed.ncbi.nlm.nih.gov/35965006
Autor:
David G. Nickens, Matthew L. Bochman
Publikováno v:
Methods (San Diego, Calif.). 204
DNA helicases function in many types of nucleic acid transactions, and as such, they are vital for genome integrity. Although they are often considered individually, work from many groups demonstrates that these enzymes often genetically and biochemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d997d94e821167211e9630f6a098e84b
https://pubmed.ncbi.nlm.nih.gov/35483549
https://pubmed.ncbi.nlm.nih.gov/35483549
Autor:
Matthew L. Bochman, David G. Nickens
Publikováno v:
Methods Enzymol
Methods in Enzymology ISBN: 9780323907330
Methods in Enzymology ISBN: 9780323907330
Eukaryotes with linear chromosomes circumvent the end replication problem via the action of a specialized ribonucleoprotein reverse transcriptase known as telomerase. Cells lacking telomerase activity will senesce when their chromosome ends shorten t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5317fba5c981a9bb7d3a2f2c84f65534
https://pubmed.ncbi.nlm.nih.gov/34776218
https://pubmed.ncbi.nlm.nih.gov/34776218
Autor:
Fábio Pereira Leivas Leite, David J. Sun, Matthew L. Bochman, David G. Nickens, Renan Eugênio Araujo Piraine
Thousands of yeasts have the potential for industrial application, though many were initially considered contaminants in the beer industry. However, these organisms are currently considered important components in beers because they contribute new fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47f0e2b3925cabaf71cd58f620eaa20d
https://doi.org/10.1101/2021.07.21.453216
https://doi.org/10.1101/2021.07.21.453216
Publikováno v:
Journal of Biological Chemistry. 293:14481-14496
Telomere length homeostasis is vital to maintaining genomic stability and is regulated by multiple factors, including telomerase activity and DNA helicases. TheSaccharomyces cerevisiaePif1 helicase was the first discovered catalytic inhibitor of telo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d298e372c4bf1e50b9f2162e31d752
https://doi.org/10.1074/jbc.ra118.004092
https://doi.org/10.1074/jbc.ra118.004092
Publikováno v:
Food microbiology. 82
We previously reported the isolation a suite of wild lactic acid-producing yeasts (LAYs) that enable “primary souring” during beer fermentation without the use of lactic acid bacteria. With sour meads gaining popularity in modern mead making, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79caf211570ec74129cd20539359932e
https://pubmed.ncbi.nlm.nih.gov/31027799
https://pubmed.ncbi.nlm.nih.gov/31027799
Publikováno v:
Nucleic Acids Research
Accommodation of donor and acceptor substrates is critical to the catalysis of (thio)phosphoryl group transfer, but there has been no systematic study of donor nucleotide recognition by kinase ribozymes, and there is relatively little known about the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a07b051224401411bb2ea0127738484
http://europepmc.org/articles/PMC2965213
http://europepmc.org/articles/PMC2965213
Publikováno v:
RNA Biology. 3:163-169
Pausing by reverse transcriptase (RT) during retroviral replication increases the frequency of homologous strand transfer, nucleotide misincorporation, and non-templated nucleotide addition. Pausing frequency increases at sites of DNA damage or upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847de056a2ab7324b69ef14825704695
https://doi.org/10.4161/rna.3.4.4020
https://doi.org/10.4161/rna.3.4.4020
Publikováno v:
RNA. 9:1029-1033
A better understanding of aptamer function in bacteria would help to establish simple model systems for screening RNA–protein interactions within an intracellular context. Escherichia coli DNA polymerase I mutants (Pol Its) fail to grow at 37°C un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2109a709a28054f5d6da1a57ddd4d3
https://doi.org/10.1261/rna.5550103
https://doi.org/10.1261/rna.5550103