Aerodynamic optimization of the exhaust system of an aft-mounted boundary layer ingestion propulsor

Autor: Jesús Matesanz-García, Tommaso Piovesan, David G. MacManus

Publikováno v: International Journal of Numerical Methods for Heat & Fluid Flow. 33:1295-1318

Purpose Novel aircraft propulsion configurations require a greater integration of the propulsive system with the airframe. As a consequence of the closer integration of the propulsive system, higher levels of flow distortion at the fan face are expec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabbd495ec8913ae00df1fe1d0992c51
https://doi.org/10.1108/hff-06-2022-0362

Safety and efficacy of bexarotene in patients with relapsing-remitting multiple sclerosis (CCMR One): a randomised, double-blind, placebo-controlled, parallel-group, phase 2a study

Autor: Charles ffrench-Constant, David G. MacManus, Jonathan Stutters, Owen R Pearson, DT Chard, Baris Kanber, Edward Needham, Zoya Georgieva, Joanne L. Jones, David Rog, Alasdair Coles, Rebecca S. Samson, Claudia A. M. Wheeler-Kingshott, J William L Brown, Ferran Prados, Peter Connick, Andrew W. Michell, Siddharthan Chandran, James Overell, Daniel R. Altmann, Paul D Flynn, Robin J.M. Franklin, Nick G Cunniffe, Carla Moran

Publikováno v: Brown, J W L, Cunniffe, N G, Prados, F, Kanber, B, Jones, J L, Needham, E, Georgieva, Z, Rog, D, Pearson, O R, Overell, J, Macmanus, D, Samson, R S, Stutters, J, Ffrench-constant, C, Gandini Wheeler-kingshott, C A M, Moran, C, Flynn, P D, Michell, A W, Franklin, R J M, Chandran, S, Altmann, D R, Chard, D T, Connick, P & Coles, A J 2021, ' Safety and efficacy of bexarotene in patients with relapsing-remitting multiple sclerosis (CCMR One): a randomised, double-blind, placebo-controlled, parallel-group, phase 2a study ', The Lancet Neurology, vol. 20, no. 9, pp. 709-720 . https://doi.org/10.1016/S1474-4422(21)00179-4

Summary Background Progressive disability in multiple sclerosis occurs because CNS axons degenerate as a late consequence of demyelination. In animals, retinoic acid receptor RXR-gamma agonists promote remyelination. We aimed to assess the safety and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d23ac9c1ac3d67ed9a8f869f9bb4d7
https://doi.org/10.1016/s1474-4422(21)00179-4

Framework for estimation of nacelle drag on isolated aero-engines with separate jets

Autor: Santiago Ramirez-Rubio, David G. MacManus

Publikováno v: Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering. 234:2025-2040

Typically, the evaluation of nacelle drag in preliminary design is required to find an overall optimum engine cycle and flight trajectory. This work focuses on the drag characteristics of aero-engine nacelles with separate jet exhausts. The main body

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda32dcdae7a86e2970743bb58454ccc
https://doi.org/10.1177/0954410020922928

Numerical investigation of the unsteady distortion for an Sduct intake with mechanical vortex generators

Autor: Geoffrey Tanguy, David G. MacManus, Eric Garnier

Publikováno v: International Journal of Heat and Fluid Flow
International Journal of Heat and Fluid Flow, 2022, 95, pp.108975. ⟨10.1016/j.ijheatfluidflow.2022.108975⟩
International Journal of Heat and Fluid Flow, Elsevier, 2022, 95, pp.108975. ⟨10.1016/j.ijheatfluidflow.2022.108975⟩

International audience; Flow control devices are used within complex intakes to reduce the flow distortion which can adversely impact the stability and performance of embedded engines. There is a need to assess the capability of modern computational

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59796b0a3914480cf7afd3679476a699
https://hal.science/hal-03714576

Surrogate models for the prediction of the aerodynamic performance of exhaust systems

Autor: Ioannis Goulos, Giorgio Giangaspero, David G. MacManus

Publikováno v: Aerospace Science and Technology. 92:77-90

The aerodynamic performance of the exhaust system is becoming more important in the design of engines for civil aircraft applications. To increase propulsive efficiency and reduce specific fuel consumption, it is expected that future engines will ope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3be460b1c8bb9dc0ecc1ff0731007d
https://doi.org/10.1016/j.ast.2019.05.027