Výsledky vyhledávání - "David G C Owens"

Akademický článek

Evaluation of a screening instrument for autism spectrum disorders in prisoners.

Autor: Louise Robinson, Michael D Spencer, Lindsay D G Thomson, Andrew C Stanfield, David G C Owens, Jeremy Hall, Eve C Johnstone

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e36078 (2012)

UNLABELLED: There have been concerns that individuals with autism spectrum disorders (ASDs) are over-represented but not recognised in prison populations. A screening tool for ASDs in prisons has therefore been developed. AIMS: We aimed to evaluate t

Externí odkaz: https://doaj.org/article/80d89fd44a8c4d419b58313405ae2d37

Zobrazit plný text záznamu

Sodium valproate in psychiatric practice: time for a change in perception

Autor: David G. C. Owens

Publikováno v: British Journal of Psychiatry. 215:516-518

SummarySodium valproate and related preparations have recently undergone regulatory review following concern about effects on the unborn child and doctors' failure to communicate risk. The issues are wider. Valproate is overused in psychiatry based o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4339c4da85230a3e0478606e3447c153
https://doi.org/10.1192/bjp.2019.137

Zobrazit plný text záznamu

Predictors of psychotic symptoms among young people with special educational needs

Autor: Eve C. Johnstone, Stephen M. Lawrie, David G. C. Owens, Andrew McKechanie, Andrew C. Stanfield

Publikováno v: The British journal of psychiatry : the journal of mental science. 215(1)

BackgroundPsychotic symptoms and psychotic disorders occur at increased rates in adults with intellectual disability, including borderline intellectual functioning, compared with the general population. Little is known about the development of such s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1685f66d4d43f1009b914f6ede3f59
https://pubmed.ncbi.nlm.nih.gov/30693855

Zobrazit plný text záznamu

Childhood adversity and hippocampal and amygdala volumes in a population at familial high risk of schizophrenia

Autor: Stephen M. Lawrie, Emma Neilson, Heather C. Whalley, Eve C. Johnstone, Catherine Bois, Andrew M. McIntosh, David G. C. Owens, Victoria Barker

Publikováno v: Barker, V, Bois, C, Neilson, E, Johnstone, E C, Owens, D, Whalley, H, McIntosh, A & Lawrie, S 2016, ' Childhood adversity and hippocampal and amygdala volumes in a population at familial high risk of schizophrenia ', Schizophrenia Research . https://doi.org/10.1016/j.schres.2016.04.028

Background There is an established link between childhood adversity (CA) and schizophrenia. Hippocampus and amygdala abnormalities pre-date onset in those at high familial risk (fHR) of schizophrenia, but it is not clear whether these alterations are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd51e29e165567651623528771afcb97
https://doi.org/10.1016/j.schres.2016.04.028

Zobrazit plný text záznamu

Negative symptoms and longitudinal grey matter tissue loss in adolescents at risk of psychosis: Preliminary findings from a 6-year follow-up study

Autor: Andrew C. Stanfield, Stephen M. Lawrie, David G. C. Owens, Heather C. Whalley, T.W. Moorhead, Eve C. Johnstone, Andrew McKechanie

Publikováno v: McKechanie, A, Moorhead, T W J, Stanfield, A C, Whalley, H C, Johnstone, E, Lawrie, S M & Owens, D G C 2016, ' Negative symptoms and longitudinal gray matter tissue loss in adolescents at risk of psychosis : Preliminary findings from a 6-year follow-up study. ', British Journal of Psychiatry, vol. 208, no. 6, pp. 565-570 . https://doi.org/10.1192/bjp.bp.114.154526

BackgroundNegative symptoms are perhaps the most disabling feature of schizophrenia. Their pathogenesis remains poorly understood and it has been difficult to assess their development over time with imaging techniques.AimsTo examine, using tensor-bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddffb2e9f6ff1a6e6af855b82ebe134
https://doi.org/10.1192/bjp.bp.114.154526

Zobrazit plný text záznamu

The development of antipsychotic drugs

Autor: David G. C. Owens, Eve C. Johnstone

Publikováno v: Brain and Neuroscience Advances

Antipsychotic drugs revolutionised psychiatric practice and provided a range of tools for exploring brain function in health and disease. Their development and introduction were largely empirical but based on long and honourable scientific credential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f504472121a16e5a506b87fa17488180
http://europepmc.org/articles/PMC7058266

Zobrazit plný text záznamu

Childhood adversity and cortical thickness and surface area in a population at familial high risk of schizophrenia

Autor: Heather C. Whalley, Eve C. Johnstone, Andrew M. McIntosh, David G. C. Owens, Catherine Bois, Victoria Barker, Stephen M. Lawrie

Publikováno v: Psychological Medicine. 46:891-896

BackgroundThere is now a well-established link between childhood adversity (CA) and schizophrenia. Similar structural abnormalities to those found in schizophrenia including alterations in grey-matter volume have also been shown in those who experien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe5e6781ddfa4ca40a021a8ca7aa380
https://doi.org/10.1017/s0033291715002585

Zobrazit plný text záznamu

Polygenic risk for schizophrenia, transition and cortical gyrification: a high-risk study

Autor: Lisa Hall, Emma Neilson, Catherine Bois, Eve C. Johnstone, Stephen M. Lawrie, Toni-Kim Clarke, Andrew M. McIntosh, David G. C. Owens, Heather C. Whalley

Publikováno v: Neilson, E, Bois, C, Clarke, T-K, Hall, L, Johnstone, E C, Owens, D G C, Whalley, H C, McIntosh, A M & Lawrie, S M 2018, ' Polygenic risk for schizophrenia, transition and cortical gyrification : a high-risk study ', Psychological Medicine, vol. 48, no. 9, pp. 1532-1539 . https://doi.org/10.1017/S0033291717003087

BackgroundSchizophrenia is a highly heritable disorder, linked to several structural abnormalities of the brain. More specifically, previous findings have suggested that increased gyrification in frontal and temporal regions are implicated in the pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b832fed486651b225136a43100feb0e
https://pubmed.ncbi.nlm.nih.gov/29065934

Zobrazit plný text záznamu

The application of nonlinear Dynamic Causal Modelling for fMRI in subjects at high genetic risk of schizophrenia

Autor: Eve C. Johnstone, Vincent Valton, Thomas W.J. Moorhead, Stephen M. Lawrie, David G. C. Owens, Heather C. Whalley, Liana Romaniuk, Maria R. Dauvermann

Publikováno v: NeuroImage. 73:16-29

Nonlinear Dynamic Causal Modelling (DCM) for fMRI provides computational modelling of gating mechanisms at the neuronal population level. It allows for estimations of connection strengths with nonlinear modulation within task-dependent networks. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cc3ddecfec9f20d06421dae3b9a3b8
https://doi.org/10.1016/j.neuroimage.2013.01.063

Zobrazit plný text záznamu

Improved individualized prediction of schizophrenia in subjects at familial high risk, based on neuroanatomical data, schizotypal and neurocognitive features

Autor: Amos Storkey, Eve C. Johnstone, David G. C. Owens, Stephen M. Lawrie, Eleni Zarogianni

Publikováno v: Zarogianni, E, Storkey, A J, Johnstone, E C, Owens, D G C & Lawrie, S M 2016, ' Improved individualized prediction of schizophrenia in subjects at familial high risk, based on neuroanatomical data, schizotypal and neurocognitive features ', Schizophrenia Research . https://doi.org/10.1016/j.schres.2016.08.027

To date, there are no reliable markers for predicting onset of schizophrenia in individuals at high risk (HR). Substantial promise is, however, shown by a variety of pattern classification approaches to neuroimaging data. Here, we examined the predic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70c49e4c20fbcba614bd9e813f408ed
https://pubmed.ncbi.nlm.nih.gov/27613509

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání