Zobrazeno 1 - 10
of 35
pro vyhledávání: '"David G, Oscier"'
Autor:
Amatta Mirandari, Helen Parker, Margaret Ashton-Key, Benjamin Stevens, Renata Walewska, Kostas Stamatopoulos, Dean Bryant, David G. Oscier, Jane Gibson, Jonathan C. Strefford
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 5, Iss 4, Pp 877-901 (2024)
Splenic marginal zone lymphoma (SMZL) is a rare, predominantly indolent B-cell lymphoma constituting fewer than 2% of lymphoid neoplasms. However, around 30% of patients have a shorter survival despite currently available treatments and the prognosis
Externí odkaz:
https://doaj.org/article/ad841940a5e44526b382eb52d66bee83
Autor:
Tomasz K. Wojdacz, Harindra E. Amarasinghe, Latha Kadalayil, Alice Beattie, Jade Forster, Stuart J. Blakemore, Helen Parker, Dean Bryant, Marta Larrayoz, Ruth Clifford, Pauline Robbe, Zadie A. Davis, Monica Else, Dena R. Howard, Basile Stamatopoulos, Andrew J. Steele, Richard Rosenquist, Andrew Collins, Andrew R. Pettitt, Peter Hillmen, Christoph Plass, Anna Schuh, Daniel Catovsky, David G. Oscier, Matthew J.J. Rose-Zerilli, Christopher C. Oakes, Jonathan C. Strefford
Publikováno v:
Blood Advances, Vol 3, Iss 16, Pp 2474-2481 (2019)
Abstract: Chronic lymphocytic leukemia patients with mutated immunoglobulin heavy-chain genes (IGHV-M), particularly those lacking poor-risk genomic lesions, often respond well to chemoimmunotherapy (CIT). DNA methylation profiling can subdivide earl
Externí odkaz:
https://doaj.org/article/cd01b8a978aa4041a72a417cc4cb4fcc
Autor:
Helen Parker, Neil Robert McIver-Brown, Zadie A. Davis, Marina Parry, Matthew J.J. Rose-Zerilli, Aliki Xochelli, Jane Gibson, Renata Walewska, Jonathan C. Strefford, David G. Oscier
Publikováno v:
Blood Advances, Vol 2, Iss 10, Pp 1116-1119 (2018)
Externí odkaz:
https://doaj.org/article/2ecc2a1690904e30943e5cee42833529
Autor:
Robert Brown, Richard Soutar, Heather G. Jorgensen, Joanne C. Mountford, Anne M. Dickinson, Tim Eden, Stefan Meyer, Junia V. Melo, David G. Oscier, Anton Parker, Alyson Sim, Tessa L. Holyoake, Gordon Strathdee
Supplementary Table S2 from Inactivation of HOXA Genes by Hypermethylation in Myeloid and Lymphoid Malignancy is Frequent and Associated with Poor Prognosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47270a3ae046c13b679ff7d0ad94e7e4
https://doi.org/10.1158/1078-0432.22440031
https://doi.org/10.1158/1078-0432.22440031
Autor:
Andrew R. Pettitt, Daniel Catovsky, David G. Oscier, Claire Dearden, Estella Matutes, David Gonzalez, Sue Richards, Rachel Wade, Melanie Oates, Anthony Carter, Gillian G. Johnson, Janet Adamson, Ke Lin
Purpose: This study sought to establish whether functional analysis of the ATM-p53-p21 pathway adds to the information provided by currently available prognostic factors in patients with chronic lymphocytic leukemia (CLL) requiring frontline chemothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f40a111844ca7e09b6f94cf5f72ac22
https://doi.org/10.1158/1078-0432.c.6519972
https://doi.org/10.1158/1078-0432.c.6519972
Autor:
Andrew R. Pettitt, Daniel Catovsky, David G. Oscier, Claire Dearden, Estella Matutes, David Gonzalez, Sue Richards, Rachel Wade, Melanie Oates, Anthony Carter, Gillian G. Johnson, Janet Adamson, Ke Lin
PDF file - 442K, Functional Analysis of the ATM-p53-p21 pathway in CLL4 trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4fc477fef7018fc868097ea41154ad
https://doi.org/10.1158/1078-0432.22443819.v1
https://doi.org/10.1158/1078-0432.22443819.v1
Autor:
Robert Brown, Richard Soutar, Heather G. Jorgensen, Joanne C. Mountford, Anne M. Dickinson, Tim Eden, Stefan Meyer, Junia V. Melo, David G. Oscier, Anton Parker, Alyson Sim, Tessa L. Holyoake, Gordon Strathdee
Purpose: The HOX genes comprise a large family of homeodomain-containing transcription factors, present in four separate clusters, which are key regulators of embryonic development, hematopoietic differentiation, and leukemogenesis. We aimed to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32301d9a6cb028ee15dd96f190d6305e
https://doi.org/10.1158/1078-0432.c.6517411.v1
https://doi.org/10.1158/1078-0432.c.6517411.v1
Autor:
Eloy F. Robles, Maria Mena-Varas, Laura Barrio, Sara V. Merino-Cortes, Péter Balogh, Ming-Qing Du, Takashi Akasaka, Anton Parker, Sergio Roa, Carlos Panizo, Idoia Martin-Guerrero, Reiner Siebert, Victor Segura, Xabier Agirre, Laura Macri-Pellizeri, Beatriz Aldaz, Amaia Vilas-Zornoza, Shaowei Zhang, Sarah Moody, Maria Jose Calasanz, Thomas Tousseyn, Cyril Broccardo, Pierre Brousset, Elena Campos-Sanchez, Cesar Cobaleda, Isidro Sanchez-Garcia, Jose Luis Fernandez-Luna, Ricardo Garcia-Muñoz, Esther Pena, Beatriz Bellosillo, Antonio Salar, Maria Joao Baptista, Jesús Maria Hernandez-Rivas, Marcos Gonzalez, Maria Jose Terol, Joan Climent, Antonio Ferrandez, Xavier Sagaert, Ari M. Melnick, Felipe Prosper, David G. Oscier, Yolanda R. Carrasco, Martin J. S. Dyer, Jose A. Martinez-Climent
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
The homeobox NKX2 family of transcriptional factors has been shown to regulate fundamental developmental processes. Here, the authors show that NKX2-3 is a bona fideoncogenic driver in marginal-zone B-cell lymphoma and that it promotes lymphomagenesi
Externí odkaz:
https://doaj.org/article/8577d51efbf14e6384756140937ba872
Autor:
Nils Winkelmann, Matthew Rose-Zerilli, Jade Forster, Marina Parry, Anton Parker, Anne Gardiner, Zadie Davies, Andrew J. Steele, Helen Parker, Nicholas C.P. Cross, David G. Oscier, Jonathan C. Strefford
Publikováno v:
Haematologica, Vol 100, Iss 6 (2015)
Externí odkaz:
https://doaj.org/article/f538c1b9bd6b48c89081f542513d78eb
Autor:
Matthew J.J. Rose-Zerilli, Jade Forster, Helen Parker, Anton Parker, Ana E. Rodríguez, Tracy Chaplin, Anne Gardiner, Andrew J. Steele, Andrew Collins, Bryan D. Young, Anna Skowronska, Daniel Catovsky, Tatjana Stankovic, David G. Oscier, Jonathan C. Strefford
Publikováno v:
Haematologica, Vol 99, Iss 4 (2014)
ATM mutation and BIRC3 deletion and/or mutation have independently been shown to have prognostic significance in chronic lymphocytic leukemia. However, the relative clinical importance of these abnormalities in patients with a deletion of 11q encompa
Externí odkaz:
https://doaj.org/article/66caa2d4337b42a0aed41826a722d99f