Zobrazeno 1 - 10
of 396
pro vyhledávání: '"David G, Kiely"'
Autor:
Charlie Elliot, Krit Dwivedi, Dheyaa Alkanfar, Michael Sharkey, Catherine Hill, Thanos Charalampololous, Robin Condliffe, Smitha Rajaram, Andrew J. Swift, David G. Kiely, Christopher S. Johns, Ze Ming Goh, Samual Barnes, Tarik Julius
Publikováno v:
Wellcome Open Research, Vol 6 (2024)
Background Computed tomography pulmonary angiography (CTPA) has been proposed to be diagnostic for pulmonary hypertension (PH) in multiple studies. However, the utility of the unenhanced CT measurements diagnosing PH has not been fully assessed. This
Externí odkaz:
https://doaj.org/article/c382f1f9d45d497a821dab0e95892709
Autor:
Anna Ulrich, Yukyee Wu, Harmen Draisma, John Wharton, Emilia M. Swietlik, Inês Cebola, Eleni Vasilaki, Zhanna Balkhiyarova, Marjo-Riitta Jarvelin, Juha Auvinen, Karl-Heinz Herzig, J. Gerry Coghlan, James Lordan, Colin Church, Luke S. Howard, Joanna Pepke-Zaba, Mark Toshner, Stephen J. Wort, David G. Kiely, Robin Condliffe, Allan Lawrie, Stefan Gräf, Nicholas W. Morrell, Martin R. Wilkins, Inga Prokopenko, Christopher J. Rhodes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Pulmonary arterial hypertension (PAH) is characterised by pulmonary vascular remodelling causing premature death from right heart failure. Established DNA variants influence PAH risk, but susceptibility from epigenetic changes is unknown. We
Externí odkaz:
https://doaj.org/article/8e50277bf2c448aa930fb3478374f053
Autor:
Adam Torbicki, Richard Channick, Nazzareno Galiè, David G. Kiely, Pamela Moceri, Andrew Peacock, Andrew J. Swift, Ahmed Tawakol, Anton Vonk Noordegraaf, Dayana Flores, Nicolas Martin, Stephan Rosenkranz
Publikováno v:
Cardiology and Therapy, Vol 13, Iss 1, Pp 173-190 (2024)
Abstract Introduction The aim of this sub-study was to evaluate the relationship between echocardiography (echo) and cardiac magnetic resonance imaging (cMRI) variables and to utilize echo to assess the effect of macitentan on right ventricle (RV) st
Externí odkaz:
https://doaj.org/article/7df83afa62ac49a88624dd7ed2aeb16a
Publikováno v:
Advances in Respiratory Medicine, Vol 92, Iss 1, Pp 45-57 (2024)
Chronic thromboembolic pulmonary disease (CTEPD) is a complication of pulmonary embolism (PE). We conducted an online survey of UK PE-treating physicians to understand practices in the follow-up of PE and awareness of CTEPD. The physicians surveyed (
Externí odkaz:
https://doaj.org/article/983e2587edd7415b80f43adc16493724
Autor:
Allan Lawrie, Kelly Chin, Yiu‐Lian Fong, Cynthia Gargano, Xavier Gitton, Cheng He, David G. Kiely, Li Zhou, Lihan Zhou, Bradley A. Maron, Debbie Quinn, Stephan Rosenkranz, Dimitri Stamatiadis, Mark Toshner, Martin R. Wilkins, Luke Howard, Ioana R. Preston
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract A blood test identifying patients at increased risk of pulmonary hypertension (PH) could streamline the investigative pathway. The prospective, multicenter CIPHER study aimed to develop a microRNA‐based signature for detecting PH in breath
Externí odkaz:
https://doaj.org/article/b8ab45400a204fd294105f2eb5f0f631
Autor:
Lojain Abdulaal, Ahmed Maiter, Mahan Salehi, Michael Sharkey, Turki Alnasser, Pankaj Garg, Smitha Rajaram, Catherine Hill, Christopher Johns, Alex Matthew Knox Rothman, Krit Dwivedi, David G. Kiely, Samer Alabed, Andrew James Swift
Publikováno v:
Frontiers in Radiology, Vol 4 (2024)
BackgroundChronic pulmonary embolism (PE) may result in pulmonary hypertension (CTEPH). Automated CT pulmonary angiography (CTPA) interpretation using artificial intelligence (AI) tools has the potential for improving diagnostic accuracy, reducing de
Externí odkaz:
https://doaj.org/article/b535f80e113f4662891fd5d96333ce2f
Autor:
David G. Kiely, Richard Channick, Dayana Flores, Nazzareno Galiè, Gwen MacDonald, J. Tim Marcus, Lada Mitchell, Andrew Peacock, Stephan Rosenkranz, Ahmed Tawakol, Adam Torbicki, Anton Vonk Noordegraaf, Andrew J. Swift
Publikováno v:
ERJ Open Research, Vol 10, Iss 1 (2024)
Background Measures that can detect large treatment effects are important for monitoring therapeutic effectiveness. The 2022 European Society of Cardiology/European Respiratory Society guidelines highlight the importance of imaging in monitoring dise
Externí odkaz:
https://doaj.org/article/028932a67c254af8be18df19775b335d
Autor:
Frances Varian, Jennifer Dick, Christian Battersby, Stefan Roman, Jenna Ablott, Lisa Watson, Sarah Binmahfooz, Hamza Zafar, Gerry Colgan, John Cannon, Jay Suntharalingam, Jim Lordan, Luke Howard, Colm McCabe, John Wort, Laura Price, Colin Church, Neil Hamilton, Iain Armstrong, Abdul Hameed, Judith Hurdman, Charlie Elliot, Robin Condliffe, Martin Wilkins, Alastair Webb, David Adlam, Ray L. Benza, Kazem Rahimi, Mohadeseh Shojaei‐Shahrokhabadi, Nan X. Lin, James M. S. Wason, Alasdair McIntosh, Alex McConnachie, Jennifer T. Middleton, Roger Thompson, David G. Kiely, Mark Toshner, Alexander Rothman
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Approved therapies for the treatment of patients with pulmonary arterial hypertension (PAH) mediate pulmonary vascular vasodilatation by targeting distinct biological pathways. International guidelines recommend that patients with an inadequ
Externí odkaz:
https://doaj.org/article/c52635068f23481e953b6d13c82baf53
Autor:
David G Kiely, Iain Armstrong, Robin Condliffe, Andrew J Swift, Allan Lawrie, Rafael Sauter, Jim Wild, Athanasios Charalampopoulos, Alex Rothman, Abdul Hameed, Smitha Rajaram, Judith Hurdman, Catherine Billings, Charlie Elliot, AA Roger Thompson, Robert A Lewis, Lisa Watson, Neil Hamilton, Steven Wood, Charlotte Durrington, Fernando Exposto, Ruvimbo Muzwidzwa, Louise Raiteri, Amélie Beaudet, Audrey Muller, Nadia Pillai, Rehan Quadery
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Objectives This study was conducted to evaluate the ability of risk assessment to predict healthcare resource utilisation (HCRU), costs, treatments, health-related quality of life (HRQoL) and survival in patients diagnosed with chronic thromboembolic
Externí odkaz:
https://doaj.org/article/3993aaf4b13943c7be76f4d6a5b3da06
Autor:
Dheyaa Alkhanfar, Krit Dwivedi, Faisal Alandejani, Yousef Shahin, Samer Alabed, Chris Johns, Pankaj Garg, A. A. Roger Thompson, Alexander M. K. Rothman, Abdul Hameed, Athanasios Charalampopoulos, Jim M. Wild, Robin Condliffe, David G. Kiely, Andrew J. Swift
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionSevere pulmonary hypertension (mean pulmonary artery pressure ≥35 mmHg) in chronic lung disease (PH-CLD) is associated with high mortality and morbidity. Data suggesting potential response to vasodilator therapy in patients with PH-CLD
Externí odkaz:
https://doaj.org/article/8a0b7e2af820457c84af45ea9b632f88