Zobrazeno 1 - 10
of 11
pro vyhledávání: '"David Fernandez De Sevilla"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
ABSTRACTAcetylcholine (ACh) regulates network operation in the hippocampus by controlling excitation and inhibition in rat CA1 pyramidal neurons (PCs), the latter through gamma-aminobutyric acid type-A receptors (GABAARs). Although, the enhancing eff
Externí odkaz:
https://doaj.org/article/33d098ac5c304b29b2b2450948909b7e
Autor:
Marta Navarrete, Gertrudis Perea, David Fernandez de Sevilla, Marta Gómez-Gonzalo, Angel Núñez, Eduardo D Martín, Alfonso Araque
Publikováno v:
PLoS Biology, Vol 10, Iss 2, p e1001259 (2012)
Long-term potentiation (LTP) of synaptic transmission represents the cellular basis of learning and memory. Astrocytes have been shown to regulate synaptic transmission and plasticity. However, their involvement in specific physiological processes th
Externí odkaz:
https://doaj.org/article/374036e31dbf43c7bb62d9168080e029
Autor:
Irene Maroto, Carlos Costas-Insua, Coralie Berthoux, Estefania Moreno, Andrea Ruiz-Calvo, Carlos Montero-Fernández, Andrea Macías-Camero, Ricardo Martín, Nuria García-Font, José Sánchez-Prieto, Giovanni Marsicano, Luigi Bellocchio, Enric Canela, Vicent Casado, Ismael Galve-Roperh, David Fernandez de Sevilla, Ignacio Rodríguez-Crespo, Pablo Castillo, Manuel Guzmán
The type-1 cannabinoid receptor (CB1R) is widely expressed in both excitatory and inhibitory nerve terminals, and its activation, by suppressing neurotransmitter release, modulates neural circuits and brain function. While the interaction of CB1R wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbe7ee7b82e20f34c072bc9d419c1894
https://doi.org/10.21203/rs.3.rs-2128033/v1
https://doi.org/10.21203/rs.3.rs-2128033/v1
Autor:
María Portela-Lomba, Diana Simón, Marta Callejo-Móstoles, Gemma de la Fuente, David Fernández de Sevilla, Vega García-Escudero, M. Teresa Moreno-Flores, Javier Sierra
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-11 (2024)
Abstract A recent approach to promote central nervous system (CNS) regeneration after injury or disease is direct conversion of somatic cells to neurons. This is achieved by transduction of viral vectors that express neurogenic transcription factors.
Externí odkaz:
https://doaj.org/article/d2f411dcb97f4a008abac9ee9aca31ce
Autor:
José Antonio Noriega-Prieto, Laura Eva Maglio, Paloma Perez-Domper, José Carlos Dávila, Antonia Gutiérrez, Ignacio Torres-Alemán, David Fernández de Sevilla
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Insulin-like growth factor-I (IGF-I) plays a key role in the modulation of synaptic plasticity and is an essential factor in learning and memory processes. However, during aging, IGF-I levels are decreased, and the effect of this decrease in the indu
Externí odkaz:
https://doaj.org/article/a49a8675cbde4d53851bc82568d2d635
Autor:
Irene B. Maroto, Carlos Costas-Insua, Coralie Berthoux, Estefanía Moreno, Andrea Ruiz-Calvo, Carlos Montero-Fernández, Andrea Macías-Camero, Ricardo Martín, Nuria García-Font, José Sánchez-Prieto, Giovanni Marsicano, Luigi Bellocchio, Enric I. Canela, Vicent Casadó, Ismael Galve-Roperh, Ángel Núñez, David Fernández de Sevilla, Ignacio Rodríguez-Crespo, Pablo E. Castillo, Manuel Guzmán
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The type-1 cannabinoid receptor (CB1R) is widely expressed in excitatory and inhibitory nerve terminals, and by suppressing neurotransmitter release, its activation modulates neural circuits and brain function. While the interaction of CB1R
Externí odkaz:
https://doaj.org/article/de2f897065d34da0933b217db4f53983
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S319- (2023)
Externí odkaz:
https://doaj.org/article/c88021e9c82b4a069bd811a6b4725e64
Autor:
María Portela-Lomba, Diana Simón, David Fernández de Sevilla, Mª Teresa Moreno-Flores, Javier Sierra
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
An approach to generate new neurons after central nervous system injury or disease is direct reprogramming of the individual's own somatic cells into differentiated neurons. This can be achieved either by transduction of viral vectors that express ne
Externí odkaz:
https://doaj.org/article/8add2b1e57b647c6b4dd150d5303f65a
Autor:
Laura E Maglio, José A Noriega-Prieto, Irene B Maroto, Jesús Martin-Cortecero, Antonio Muñoz-Callejas, Marta Callejo-Móstoles, David Fernández de Sevilla
Publikováno v:
eLife, Vol 10 (2021)
Insulin-like growth factor-1 (IGF-1) plays a key role in synaptic plasticity, spatial learning, and anxiety-like behavioral processes. While IGF-1 regulates neuronal firing and synaptic transmission in many areas of the central nervous system, its si
Externí odkaz:
https://doaj.org/article/4f62044224414736b4d2eefc48745254
Autor:
José Antonio Noriega-Prieto, Laura Eva Maglio, Sara Ibáñez-Santana, David Fernández de Sevilla
Publikováno v:
Cells, Vol 11, Iss 10, p 1641 (2022)
Insulin-like growth factor-I (IGF-I) signaling plays a key role in learning and memory. IGF-I increases the spiking and induces synaptic plasticity in the mice barrel cortex (Noriega-Prieto et al., 2021), favoring the induction of the long-term poten
Externí odkaz:
https://doaj.org/article/85362226f1834d2a970d4af97b2fc436