Zobrazeno 1 - 10
of 48
pro vyhledávání: '"David Fenyő"'
Autor:
Natália Pinto de Almeida, Ágnes Judit Jánosi, Runyu Hong, Ahmad Rajeh, Fábio Nogueira, Leticia Szadai, Beata Szeitz, Indira Pla Parada, Viktória Doma, Nicole Woldmar, Jéssica Guedes, Zsuzsanna Újfaludi, Aron Bartha, Yonghyo Kim, Charlotte Welinder, Bo Baldetorp, Lajos Vince Kemény, Zoltan Pahi, Guihong Wan, Nga Nguyen, Tibor Pankotai, Balázs Győrffy, Krzysztof Pawłowski, Peter Horvatovich, Attila Marcell Szasz, Aniel Sanchez, Magdalena Kuras, Jimmy Rodriguez Murillo, Lazaro Betancourt, Gilberto B. Domont, Yevgeniy R. Semenov, Kun‐Hsing Yu, Ho Jeong Kwon, István Balázs Németh, David Fenyő, Elisabet Wieslander, György Marko‐Varga, Jeovanis Gil
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 7, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/205bd0d51fdf4b4b93dd4253f0c90a12
Autor:
Liana Goehring, Sarah Keegan, Sudipta Lahiri, Wenxin Xia, Michael Kong, Judit Jimenez-Sainz, Dipika Gupta, Ronny Drapkin, Ryan B. Jensen, Duncan J. Smith, Eli Rothenberg, David Fenyö, Tony T. Huang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract BRCA2 is a tumor suppressor protein responsible for safeguarding the cellular genome from replication stress and genotoxicity, but the specific mechanism(s) by which this is achieved to prevent early oncogenesis remains unclear. Here, we pro
Externí odkaz:
https://doaj.org/article/6eae7c91ca5e4e60a5079c4501597601
Autor:
Leandro Y. S. Okimoto, Rayol Mendonca-Neto, Fabíola G. Nakamura, Eduardo F. Nakamura, David Fenyö, Claudio T. Silva
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract Background In recent years, researchers have made significant strides in understanding the heterogeneity of breast cancer and its various subtypes. However, the wealth of genomic and proteomic data available today necessitates efficient fram
Externí odkaz:
https://doaj.org/article/bba6169bf35f424e8bdadd9761e3f47f
Autor:
Leticia Szadai, Aron Bartha, Indira Pla Parada, Alexandra I.T. Lakatos, Dorottya M.P. Pál, Anna Sára Lengyel, Natália Pinto de Almeida, Ágnes Judit Jánosi, Fábio Nogueira, Beata Szeitz, Viktória Doma, Nicole Woldmar, Jéssica Guedes, Zsuzsanna Ujfaludi, Zoltán Gábor Pahi, Tibor Pankotai, Yonghyo Kim, Balázs Győrffy, Bo Baldetorp, Charlotte Welinder, A. Marcell Szasz, Lazaro Betancourt, Jeovanis Gil, Roger Appelqvist, Ho Jeong Kwon, Sarolta Kárpáti, Magdalena Kuras, Jimmy Rodriguez Murillo, István Balázs Németh, Johan Malm, David Fenyö, Krzysztof Pawłowski, Peter Horvatovich, Elisabet Wieslander, Lajos V. Kemény, Gilberto Domont, György Marko-Varga, Aniel Sanchez
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionWhile Immune checkpoint inhibition (ICI) therapy shows significant efficacy in metastatic melanoma, only about 50% respond, lacking reliable predictive methods. We introduce a panel of six proteins aimed at predicting response to ICI ther
Externí odkaz:
https://doaj.org/article/fe95ef6a509c4265b300a1ff4e58f88f
Autor:
Yize Li, Nadezhda V. Terekhanova, Daniel Cui Zhou, Kelly V. Ruggles, Samuel H. Payne, Michael Wendl, David Fenyő, Li Ding
Publikováno v:
Cancer Research. 82:845-845
The increased quality and data availability of large-scale transcriptomic, genomic, and proteomic studies require a pan-cancer integrated proteogenomic approach to define tumor molecular signatures accurately and identify new therapeutic targets. We
Autor:
Gabriele Stephan, Sara Haddock, Shuai Wang, Hediye Erdjument-Bromage, Wenke Liu, Niklas Ravn-Boess, Joshua D. Frenster, Devin Bready, Julia Cai, Rebecca Ronnen, Jonathan Sabio-Ortiz, David Fenyo, Thomas A. Neubert, Dimitris G. Placantonakis
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114229- (2024)
Summary: GPR133 (ADGRD1) is an adhesion G-protein-coupled receptor that signals through Gαs/cyclic AMP (cAMP) and is required for the growth of glioblastoma (GBM), an aggressive brain malignancy. The regulation of GPR133 signaling is incompletely un
Externí odkaz:
https://doaj.org/article/22cad31820a94f3da72fef14f8760c05
Autor:
Rachel Ruoff, Hannah Weber, Ying Wang, Hongying Huang, Ellen Shapiro, David Fenyö, Michael J. Garabedian
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract MED19, a component of the mediator complex and a co-regulator of the androgen receptor (AR), is pivotal in prostate cancer cell proliferation. MED19 has two isoforms: a full-length “canonical” and a shorter “alternative” variant. Spe
Externí odkaz:
https://doaj.org/article/9d076138bbdb44f2b8123f663951ef45
Autor:
Karl R. Clauser, Zhen Zhang, Tao Liu, David L. Tabb, Shunqiang Li, Xian Chen, Hui Zhang, Philipp Mertins, Shisheng Sun, Matthew J. Ellis, Himanshu Grover, Raymond R. Townsend, Ling Xie, Xuya Wang, Jian-Ying Zhou, Daniel W. Chan, Harsha P. Gunawardena, Richard D. Smith, David Fenyő, Katherine A. Hoadley, Song Cao, Manor Askenazi, Steven A. Carr, Petra Erdmann-Gilmore, Samuel H. Payne, Li Ding, Zuojian Tang, Kelly V. Ruggles, Charles M. Perou, Henry Rodriguez, Christopher G. Maher, Daniel C. Liebler, Michael D. McLellan, Robbert J.C. Slebos, Karen D. Rodland, Sherri R. Davies, Christopher R. Kinsinger, Jennifer Teubl
Publikováno v:
Molecular & Cellular Proteomics. 15:1060-1071
Improvements in mass spectrometry (MS)-based peptide sequencing provide a new opportunity to determine whether polymorphisms, mutations, and splice variants identified in cancer cells are translated. Herein, we apply a proteogenomic data integration
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 11, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/9cd50dc63ee84311bb1695579de819f3
Autor:
Leticia Szadai, Jéssica de Siqueira Guedes, Nicole Woldmar, Natália Pinto deAlmeida, Ágnes Judit Jánosi, Ahmad Rajeh, Ferenc Kovács, András Kriston, Ede Migh, Guihong Wan, Nga Nguyen, Henriett Oskolás, Roger Appelqvist, Fábio CN Nogueira, Gilberto B Domont, Kun‐Hsing Yu, Eugene R. Semenov, Johan Malm, Melinda Rezeli, Elisabet Wieslander, David Fenyö, Lajos Kemény, Peter Horvath, István Balázs Németh, György Marko‐Varga, Jeovanis Gil
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 11, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/f65d8be28fd741cebded9c5880d80da1