Zobrazeno 1 - 10
of 27
pro vyhledávání: '"David F. Orr"'
Autor:
Barbara K. Pierscionek, David F. Orr, Giuliano Elia, Gwen Manning, Michael J. Dunn, J. Keenan
Publikováno v:
PROTEOMICS. 12:1830-1843
The eye lens remains transparent because of soluble lens proteins known as crystallins. For years γ-crystallins have been known as the main lens proteins in lower vertebrates such as fish and amphibians. The unique growth features of the lens render
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3f193fad2a969a4fd434da8c04e8c5
https://doi.org/10.1002/pmic.201100393
https://doi.org/10.1002/pmic.201100393
Publikováno v:
PROTEOMICS. 9:5340-5349
Protein distribution patterns across eye lenses from the Asiatic toad Bufo gargarizans were investigated and individual crystallin classes characterised. Special fractionation that follows the growth mode of the lens was used to yield nine fractions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961aabd6281be48bc5a71a9eface9b2c
https://doi.org/10.1002/pmic.200800986
https://doi.org/10.1002/pmic.200800986
Publikováno v:
Peptides. 28:1331-1343
Studies conducted on amphibian skin secretions over the past 40 years have isolated and identified huge arrays of bioactive peptides, many of which have demonstrated potent anti-microbial activity. Such peptides are attracting increasing attention du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c31fe80c102b13aaa4f13f39dec5f2
https://doi.org/10.1016/j.peptides.2007.05.001
https://doi.org/10.1016/j.peptides.2007.05.001
Publikováno v:
Peptides. 26:2117-2123
Skin secretions of Rana saharica were evaluated for the isolation and characterization of novel insulinotropic peptides. Crude secretions obtained from young adult frogs by mild electrical stimulation of the dorsal skin surface were purified by rever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b4255d8efb07cc561cb310c9413ecd
https://doi.org/10.1016/j.peptides.2005.03.008
https://doi.org/10.1016/j.peptides.2005.03.008
Publikováno v:
Journal of Peptide Research. 66:204-210
Naturally occurring insulinotropic peptides were isolated from the skin secretions of Rana pipiens frogs. Crude secretions (50 mg; 5-10 frogs) obtained by mild electrical stimulation of the dorsal skin surface were purified by reversed-phase high- pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232f9cd43f604c0050df14a19b5dbbd3
https://doi.org/10.1111/j.1399-3011.2005.00287.x
https://doi.org/10.1111/j.1399-3011.2005.00287.x
Autor:
Pingfan Rao, Tianbao Chen, Martin O'Rourke, David F. Orr, David G. Hirst, Christopher Shaw, Daniel J.M. Coulter
Publikováno v:
Regulatory Peptides. 116:147-154
We have isolated a novel bradykinin B2-receptor antagonist peptide, kinestatin, from toad (Bombina maxima) defensive skin secretion. Mass spectroscopy established a molecular mass of 931.56 Da and a provisional structure: pGlu-Leu/Ile-Pro-Gly-Leu/Ile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e697a7b465f33001b926991ebc01a9b6
https://doi.org/10.1016/j.regpep.2003.08.003
https://doi.org/10.1016/j.regpep.2003.08.003
Autor:
Anthony J. Bjourson, Tianbao Chen, Pingfan Rao, Christopher Shaw, David F. Orr, Susan Farragher
Publikováno v:
Biochemical Journal. 371:125-130
Amphibian defensive skin secretions are complex, species-specific cocktails of biologically active molecules, including many uncharacterized peptides. The study of such secretions for novel peptide discovery is time-limited, as amphibians are in rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b442d219a25be7aed499f00450dba2
https://doi.org/10.1042/bj20021343
https://doi.org/10.1042/bj20021343
Autor:
Pingfan Rao, Anthony J. Bjourson, Christopher Shaw, Hang Fai Kwok, Tianbao Chen, David F. Orr, Craig Ivanyi
Publikováno v:
Analytical Biochemistry. 311:152-156
While structural studies of reptile venom toxins can be achieved using lyophilized venom samples, until now the cloning of precursor cDNAs required sacrifice of the specimen for dissection of the venom glands. Here we describe a simple and rapid tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ea4af0e858bdf7106d128eb9e9bde6
https://doi.org/10.1016/s0003-2697(02)00404-9
https://doi.org/10.1016/s0003-2697(02)00404-9
Autor:
James M. Sloan, Rod Chalk, Keith D. Buchanan, Pingfan Rao, Anders H. Johnsen, Tianbao Chen, David F. Orr, Christopher Shaw
Publikováno v:
PROTEOMICS. 2:1586-1600
The hypothesis that chromogranin A (CgA), a protein of neuroendocrine cell secretory granules, may be a precursor of biologically active peptides, rests on observed activities of peptide fragments largely produced by exogenous protease digestion of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::206f11e52704aa114bbbb9adeebf2288
https://doi.org/10.1002/1615-9861(200211)2:11<1586::aid-prot1586>3.0.co
https://doi.org/10.1002/1615-9861(200211)2:11<1586::aid-prot1586>3.0.co
Autor:
Christopher Shaw, Martin O'Rourke, David G. Hirst, David F. Orr, Pingfan Rao, Anthony J. Bjourson, Tianbao Chen, Stephen McClean
Publikováno v:
European Journal of Biochemistry. 269:4693-4700
Two novel bradykinin-related peptides (Ala3,Thr6)-bradykinin and (Val1,Thr3,Thr6)-bradykinin, were identified by a systematic sequencing study of peptides in the defensive skin secretion of the yellow-bellied toad, Bombina variegata. These peptides a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca49716f8df9b2ce8fe3f862518ebf52
https://doi.org/10.1046/j.1432-1033.2002.03174.x
https://doi.org/10.1046/j.1432-1033.2002.03174.x