Zobrazeno 1 - 10
of 12
pro vyhledávání: '"David F. Lindsey"'
Autor:
Maxim Y Balakirev, James E Mullally, Adrien Favier, Nicole Assard, Eric Sulpice, David F Lindsey, Anastasia V Rulina, Xavier Gidrol, Keith D Wilkinson
Publikováno v:
eLife, Vol 4 (2015)
Sumoylation during genotoxic stress regulates the composition of DNA repair complexes. The yeast metalloprotease Wss1 clears chromatin-bound sumoylated proteins. Wss1 and its mammalian analog, DVC1/Spartan, belong to minigluzincins family of protease
Externí odkaz:
https://doaj.org/article/1d2327de45b944ef8e8e73046a85a414
Publikováno v:
The FASEB Journal. 32
Autor:
David F. Lindsey, Nicole Assard, Eric Sulpice, Adrien Favier, Xavier Gidrol, James E. Mullally, Anastasia V Rulina, Keith D. Wilkinson, Maxim Y Balakirev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c33a9bfddc00a076f036b25bd6d78c71
https://doi.org/10.7554/elife.06763.043
https://doi.org/10.7554/elife.06763.043
Autor:
Ryan Lunsford, Lisa McGill, Richard H. Gomer, Nathaniel Whitney, Lacey J. Pearson, David F. Lindsey
Publikováno v:
Eukaryotic Cell. 5:1820-1825
The RBR family of ubiquitin ligases is a large and complex family with members present in animals, plants, fungi, and protists (17). RBR genes have been implicated in cancer and neurodegenerative diseases (e.g., parkin) (17-19, 21). Despite significa
Publikováno v:
The FASEB Journal. 28
The ubiquitin processing protease, UbpA (a homolog of yeast Ubp14 and human IsoT/USP5), is required for the growth-to-development transition of Dictyostelium. When ubpA¯ cells starve, they accumula...
Autor:
Derrick T. Brazill, Debra A. Brock, Robin R. Ammann, R. Diane Hatton, David R. Caprette, Heather Myler, Richard H. Gomer, David F. Lindsey
Publikováno v:
Journal of Biological Chemistry. 275:19231-19240
Initial differentiation in Dictyostelium involves both asymmetric cell division and a cell cycle-dependent mechanism. We previously identified a gene, rtoA, which when disrupted randomizes the cell cycle-dependent mechanism without affecting either t
Autor:
Richard H. Gomer, John D. Bishop, William J. Deery, Alexander Y. Amerik, David F. Lindsey, Mark Hochstrasser
Publikováno v:
Journal of Biological Chemistry. 273:29178-29187
Although cell differentiation usually involves synthesis of new proteins, little is known about the role of protein degradation. In eukaryotes, conjugation to ubiquitin polymers often targets a protein for destruction. This process is regulated by de
Publikováno v:
Proceedings of the National Academy of Sciences. 93:5003-5007
We have developed a mutagenesis technique that uses antisense cDNA to identify genes required for development in Dictyostelium discoideum. We transformed Dictyostelium cells with a cDNA library made from the mRNA of vegetative and developing cells. T
Autor:
van Peter Haastert, Renu Jain, Ita S. Yuen, William J. Deery, David F. Lindsey, John D. Bishop, Richard H. Gomer
Publikováno v:
The Journal of Cell Biology
The Journal of Cell Biology, 129(5), 1251-1262. ROCKEFELLER UNIV PRESS
The Journal of Cell Biology, 129(5), 1251-1262. ROCKEFELLER UNIV PRESS
Dictyostelium discoideum initiates development when cells overgrow their bacterial food source and starve. To coordinate development, the cells monitor the extracellular level of a protein, conditioned medium factor (CMF), secreted by starved cells.
Publikováno v:
The FASEB Journal. 22