Zobrazeno 1 - 10
of 12
pro vyhledávání: '"David F. Havlicek"'
Autor:
David F Havlicek, Jonathan B Rosenberg, Bishnu P De, Martin J Hicks, Dolan Sondhi, Stephen M Kaminsky, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0239780 (2020)
The cocaine vaccine dAd5GNE is comprised of a disrupted serotype 5 adenovirus gene therapy vector covalently conjugated to the cocaine analog GNE. The vaccine evokes a high titer of circulating anti-cocaine antibodies that prevent cocaine from reachi
Externí odkaz:
https://doaj.org/article/10ec18612f4b49c6a6b6e5c8dd4f8c8b
Autor:
David F. Havlicek, Rachel Furhang, Elena Nikulina, Bayle Smith-Salzberg, Siobhán Lawless, Sasha A. Sevarin, Sevara Mallaboeva, Fizza Nayab, Alan C. Seifert, John F. Crary, Peter J. Bergold
Traumatic brain injury (TBI) acutely damages the brain; this injury can evolve into chronic neurodegeneration. While much is known about the chronic effects arising from multiple mild TBIs, far less is known about the long-term effects of a single mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a6e600f615e585c2b32b94f7586d9a6
https://doi.org/10.1101/2022.05.19.492705
https://doi.org/10.1101/2022.05.19.492705
Autor:
Katie M. Stiles, Philip L. Leopold, Vladlena Lee, Stephanie Giordano, Alvin Chen, Dolan Sondhi, Chester Bittencourt Sacramento, Ronald G. Crystal, Jonathan B. Rosenberg, Stephen M. Kaminsky, David F. Havlicek, Eduard Pey
Publikováno v:
Human Gene Therapy. 31:57-69
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disorder caused by repetitive trauma to the central nervous system (CNS) suffered by soldiers, contact sport athletes, and civilians following accident-related trauma. CTE is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2c4ee617e63721fe7d2b9a1887863a
https://doi.org/10.1089/hum.2019.174
https://doi.org/10.1089/hum.2019.174
Autor:
David F, Havlicek, Rachel, Furhang, Elena, Nikulina, Bayle, Smith-Salzberg, Siobhán, Lawless, Sasha A, Severin, Sevara, Mallaboeva, Fizza, Nayab, Alan C, Seifert, John F, Crary, Peter J, Bergold
Publikováno v:
Experimental Neurology. 359:114241
Traumatic brain injury (TBI) acutely damages the brain; this injury can evolve into chronic neurodegeneration. While much is known about the chronic effects arising from multiple mild TBIs, far less is known about the long-term effects of a single mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6934634f1c90ffa2e0c939a96a0ca9bc
https://doi.org/10.1016/j.expneurol.2022.114241
https://doi.org/10.1016/j.expneurol.2022.114241
Autor:
Ronald G. Crystal, David F. Havlicek, Bishnu P. De, Stephen M. Kaminsky, Martin J. Hicks, Dolan Sondhi, Jonathan B. Rosenberg
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0239780 (2020)
PLoS ONE, Vol 15, Iss 11, p e0239780 (2020)
The cocaine vaccine dAd5GNE is comprised of a disrupted serotype 5 adenovirus gene therapy vector covalently conjugated to the cocaine analog GNE. The vaccine evokes a high titer of circulating anti-cocaine antibodies that prevent cocaine from reachi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d188a979ae818cac3041713af477e08e
https://doi.org/10.1371/journal.pone.0239780
https://doi.org/10.1371/journal.pone.0239780
Autor:
Stephen M. Kaminsky, David F. Havlicek, Ronald G. Crystal, Jonathan B. Rosenberg, Dolan Sondhi
Publikováno v:
Biologics to Treat Substance Use Disorders ISBN: 9783319231495
Addictive drugs are a major worldwide problem, and for many there are few effective therapies. Based on the concept that high titers of drug-specific antibodies can bind to addictive drugs in the blood preventing them from crossing the blood–brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98a5a71cf437f69c2a3db7c376f5f487
https://doi.org/10.1007/978-3-319-23150-1_13
https://doi.org/10.1007/978-3-319-23150-1_13
Autor:
Bishnu P. De, Maria J. Chiuchiolo, Neil R. Hackett, Jonathan P. Dyke, Esther Z Frenk, Douglas Ballon, Martin J. Hicks, Eric Aronowitz, Ronald G. Crystal, Kosuke Funato, Dolan Sondhi, Lan Wang, Viviane Tabar, Stephen M. Kaminsky, David F. Havlicek
Publikováno v:
Cancer gene therapy
The median survival of glioblastoma multiforme (GBM) is approximately 1 year. Following surgical removal, systemic therapies are limited by the blood-brain barrier. To circumvent this, we developed a method to modify neurons with the genetic sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b3e941853960ae16aaa2d065257216
https://pubmed.ncbi.nlm.nih.gov/25501993
https://pubmed.ncbi.nlm.nih.gov/25501993
Autor:
Jonathan B. Rosenberg, Lauren M. Beatty, David F. Havlicek, Ronald G. Crystal, Stephen M. Kaminsky, Sebastien Monette, Bishnu P. De, Lucy Quach, Dolan Sondhi
Publikováno v:
Molecular Therapy. 23:S180-S181
Cocaine is a highly addictive drug with significant social, societal, economic and medical impact, yet there are no effective therapies for cocaine addiction. An anti-cocaine vaccine that could evoke antibodies to bind the drug and prevent its transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d81d660dd66982cbcc7f48f44440c7b
https://doi.org/10.1016/s1525-0016(16)34064-3
https://doi.org/10.1016/s1525-0016(16)34064-3
Autor:
David F. Havlicek, Fan Fan, Maria J. Chiuchiolo, Douglas Ballon, Ronald G. Crystal, Martin J. Hicks, Dolan Sondhi, Jonathan P. Dyke, Stephen M. Kaminsky, Kosuke Funato, Eric Aronowitz, Viviane Tabar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0162978 (2016)
PLoS ONE, Vol 11, Iss 10, p e0162978 (2016)
Glioblastoma multiforme (GBM) is the most common and aggressive primary intracranial brain tumor in adults with a mean survival of 14 to 15 months. Aberrant activation of the epidermal growth factor receptor (EGFR) plays a significant role in GBM pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b67b65deb4922bca5adf244ead4bc0
https://doi.org/10.1371/journal.pone.0162978
https://doi.org/10.1371/journal.pone.0162978
Autor:
Odelya E. Pagovich, Ronald G. Crystal, Dolan Sondhi, David F. Havlicek, Jonathan E. Rosenberg, Stephen M. Kaminsky, Bishnu P. De
Publikováno v:
Molecular Therapy. 24:S16
dAd5GNE, an anti-cocaine vaccine based on a disrupted serotype 5 adenovirus gene transfer vector covalently conjugated to the cocaine analog GNE, evokes high titers of high affinity anti-cocaine antibodies that prevent cocaine from reaching its cogna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c6e1cac2d85f6e5137050afcd6d9e7f
https://doi.org/10.1016/s1525-0016(16)32845-3
https://doi.org/10.1016/s1525-0016(16)32845-3