Zobrazeno 1 - 10
of 26
pro vyhledávání: '"David F. Gilmore"'
Publikováno v:
Antibiotics, Vol 11, Iss 7, p 939 (2022)
From a library of compounds, 11 hit antibacterial agents have been identified as potent anti-Gram-positive bacterial agents. These pyrazole derivatives are active against two groups of pathogens, staphylococci and enterococci, with minimum inhibitory
Externí odkaz:
https://doaj.org/article/b05d78aa91a643d2a687deabf0c9ba95
Autor:
Ibrahim S. Alkhaibari, Hansa Raj KC, Subrata Roy, Mohd. K. Abu-gazleh, David F. Gilmore, Mohammad A. Alam
Publikováno v:
Molecules, Vol 26, Iss 16, p 5083 (2021)
Enterococci and methicillin-resistant S. aureus (MRSA) are among the menacing bacterial pathogens. Novel antibiotics are urgently needed to tackle these antibiotic-resistant bacterial infections. This article reports the design, synthesis, and antimi
Externí odkaz:
https://doaj.org/article/c599fde3f11d4154ba971c52639a4c24
Autor:
Evan Delancey, Devin Allison, Hansa Raj KC, David F. Gilmore, Todd Fite, Alexei G. Basnakian, Mohammad A. Alam
Publikováno v:
Antibiotics, Vol 9, Iss 10, p 650 (2020)
Acinetobacter baumannii has emerged as one of the most lethal drug-resistant bacteria in recent years. We report the synthesis and antimicrobial studies of 25 new pyrazole-derived hydrazones. Some of these molecules are potent and specific inhibitors
Externí odkaz:
https://doaj.org/article/7378612825b14da4bd4e8488db5c7649
Publikováno v:
ChemMedChem. 16:2628-2637
Nootkatone, an approved insecticide, is a well-known natural product from grapefruit. A series of fused-thiazole derivatives of nootkatone have been synthesized, and these new compounds were tested against several strains of bacteria. Some of these c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74beefd49eda3665e9142de4781aff5b
https://doi.org/10.1002/cmdc.202100230
https://doi.org/10.1002/cmdc.202100230
Autor:
David F. Gilmore, Hansa Raj Kc, Mohammad A. Alam, Hashim Ali, Subrata Roy, Ibrahim Saleh, Mohd Kotaiba Abugazleh
Publikováno v:
RSC Med Chem
Design and synthesis of N-(trifluoromethyl)phenyl substituted pyrazole derivatives and their potency as antimicrobial agents are described. Several of these novel compounds are effective growth inhibitors of antibiotic-resistant Gram-positive bacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c01805449b7fbffd4e064cd6699233
https://doi.org/10.1039/d1md00230a
https://doi.org/10.1039/d1md00230a
Autor:
Steven A Chambers, Matthew Newman, Jedidiah Whitt, Mohammad A. Alam, David F. Gilmore, Rawan Alnufaie, Nickolas Alsup, Hansa Raj Kc
Publikováno v:
The Journal of antibiotics
We report the synthesis and antimicrobial studies of a new series of naphthyl-substituted pyrazole-derived hydrazones. Many of these novel compounds are potent growth inhibitors of several strains of drug-resistant bacteria. These potent compounds ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02bc1d9e1401d0b24ca43592de60f77f
https://doi.org/10.1038/s41429-020-0341-2
https://doi.org/10.1038/s41429-020-0341-2
Autor:
David F. Gilmore, Cameron Duke, Jedidiah Whitt, Steven A Chambers, Mohammad A. Alam, Mahbub Kabir Khan, Mohamad Akbar Ali
Publikováno v:
ACS Omega, Vol 4, Iss 10, Pp 14284-14293 (2019)
Microbial resistance to antibiotics is an urgent and worldwide concern. Several pyrazole-derived hydrazones were synthesized by using benign reaction conditions. Several of these molecules are potent growth inhibitors of drug-resistant strains of Sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1358c4f9daf9b4a44e6768fdc893f4b
https://doi.org/10.1021/acsomega.9b01967
https://doi.org/10.1021/acsomega.9b01967
Autor:
Raj Kc. Hansa, Alexei G. Basnakian, M.M.K. Khan, Mohammad A. Alam, David F. Gilmore, M.M. Frangie, Mark S. Smeltzer, Alena V. Savenka, R.S. Shelton, S.L. Shuttleworth
Publikováno v:
Eur J Med Chem
A collection of potent antimicrobials consisting of novel 1,3-bis-benzoic acid and trifluoromethyl phenyl derived pyrazoles has been synthesized and tested for antibacterial activity. The majority of trifluoromethyl phenyl derivatives are highly pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b1a6ebae9f00f464406f8c32c28e01
https://europepmc.org/articles/PMC8165011/
https://europepmc.org/articles/PMC8165011/
Autor:
David F. Gilmore, Devin Allison, Evan Delancey, Hansa Raj Kc, Todd Fite, Mohammad A. Alam, Alexei G. Basnakian
Publikováno v:
Antibiotics, Vol 9, Iss 650, p 650 (2020)
Antibiotics
Volume 9
Issue 10
Antibiotics
Volume 9
Issue 10
Acinetobacter baumannii has emerged as one of the most lethal drug-resistant bacteria in recent years. We report the synthesis and antimicrobial studies of 25 new pyrazole-derived hydrazones. Some of these molecules are potent and specific inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500592b86cf721534a00cc30806cc98a
https://www.mdpi.com/2079-6382/9/10/650
https://www.mdpi.com/2079-6382/9/10/650
Autor:
David F. Gilmore, Hansa Raj Kc, Steven A Chambers, Jedidiah Whitt, Rawan Alnufaie, Nickolas Alsup, Mohammad A. Alam
Publikováno v:
Molecules
Volume 25
Issue 12
Molecules, Vol 25, Iss 2758, p 2758 (2020)
Volume 25
Issue 12
Molecules, Vol 25, Iss 2758, p 2758 (2020)
In this paper, synthesis and antimicrobial studies of 31 novel coumarin-substituted pyrazole derivatives are reported. Some of these compounds have shown potent activity against methicillin-resistant Staphylococcus aureus (MRSA) with minimum inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe73845e2eba141b2b5475a6c3eb2e3c