Zobrazeno 1 - 10
of 25
pro vyhledávání: '"David F. Bruhn"'
Autor:
Taizong Wu, Waleed M. Hussein, Kaumadi Samarasekera, Yuxuan Zhu, Zeinab G. Khalil, Shengbin Jin, David F. Bruhn, Yovany Moreno, Angela A. Salim, Robert J. Capon
Publikováno v:
Marine Drugs, Vol 22, Iss 7, p 312 (2024)
A bioassay-guided chemical investigation of a bacterium, Streptomyces sp. CMB-MRB032, isolated from sheep feces collected near Bathurst, Victoria, Australia, yielded the known polyketide antimycins A4a (1) and A2a (2) as potent inhibitors of Dirofila
Externí odkaz:
https://doaj.org/article/7dfee6623d574281aa36f24706d9ac2b
Autor:
Armelle Buzy, Camille Allain, John Harrington, Dominique Lesuisse, Vincent Mikol, David F. Bruhn, Aaron G. Maule, Jean-Claude Guillemot
Publikováno v:
ACS Omega, Vol 6, Iss 15, Pp 10288-10305 (2021)
Externí odkaz:
https://doaj.org/article/0d3dfcf32203481a995ff60786dae934
Autor:
Mingming Zhang, Allan M. Prior, Marcus M. Maddox, Wan-Jou Shen, Kirk E. Hevener, David F. Bruhn, Robin B. Lee, Aman P. Singh, Justin Reinicke, Charles J. Simmons, Julian G. Hurdle, Richard E. Lee, Dianqing Sun
Publikováno v:
ACS Omega, Vol 3, Iss 12, Pp 18343-18360 (2018)
Externí odkaz:
https://doaj.org/article/27abe659138b4f32a2e630d0506d1f8f
Autor:
John Harrington, Camille Allain, Armelle Buzy, Aaron G. Maule, David F. Bruhn, Jean-Claude Guillemot, Dominique Lesuisse, Vincent Mikol
Publikováno v:
ACS Omega, Vol 6, Iss 15, Pp 10288-10305 (2021)
Buzy, A, Allain, C, Harrington, J, Lesuisse, D, Mikol, V, Bruhn, D F, Maule, A G & Guillemot, J-C 2021, ' Peptidomics of Haemonchus contortus ', ACS Omega, vol. 6, no. 15, pp. 10288-10305 . https://doi.org/10.1021/acsomega.1c00650
Buzy, A, Allain, C, Harrington, J, Lesuisse, D, Mikol, V, Bruhn, D F, Maule, A G & Guillemot, J-C 2021, ' Peptidomics of Haemonchus contortus ', ACS Omega, vol. 6, no. 15, pp. 10288-10305 . https://doi.org/10.1021/acsomega.1c00650
The nematode Haemonchus contortus (the barber's pole worm) is an endoparasite infecting wild and domesticated ruminants worldwide. Widespread anthelmintic resistance of H. contortus requires alternative strategies to control this parasite. Neuropepti
Autor:
Marcus M. Maddox, Charles J. Simmons, Mingming Zhang, Allan M. Prior, Kirk E. Hevener, David F. Bruhn, Dianqing Sun, Justin Reinicke, Julian G Hurdle, Aman P. Singh, Robin B. Lee, Wan-Jou Shen, Richard E. Lee
Publikováno v:
ACS Omega, Vol 3, Iss 12, Pp 18343-18360 (2018)
ACS Omega
ACS Omega
A series of novel chalcone and thiol-Michael addition analogues was synthesized and tested against Mycobacterium tuberculosis and other clinically significant bacterial pathogens. Previously reported chalcone-like antibacterials (1a–c and 2) were u
Autor:
Armelle, Buzy, Camille, Allain, John, Harrington, Dominique, Lesuisse, Vincent, Mikol, David F, Bruhn, Aaron G, Maule, Jean-Claude, Guillemot
Publikováno v:
ACS Omega
The nematode Haemonchus contortus (the barber’s pole worm) is an endoparasite infecting wild and domesticated ruminants worldwide. Widespread anthelmintic resistance of H. contortus requires alternative strategies to control this parasite. Neuropep
Autor:
Nisha Das, Aaron Poole, Richard E. Lee, Christopher J. Meyer, Terry L. Bowlin, Samanthi L. Waidyarachchi, Amy R. Iverson, Jason W. Rosch, Michelle M. Butler, David F. Bruhn, Peter Vogel
The most frequent ailment for which antibiotics are prescribed is otitis media (ear infections), which is most commonly caused by Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae. Treatment of otitis media is complicated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb298c983daf65867867c28042409744
https://europepmc.org/articles/PMC6496058/
https://europepmc.org/articles/PMC6496058/
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:4070-4076
Bacterial infections, caused by Mycobacterium tuberculosis and other problematic bacterial pathogens, continue to pose a significant threat to global public health. As such, new chemotype antibacterial agents are desperately needed to fuel and streng
Autor:
Yuk-Ching Tse-Dinh, Charles J. Simmons, Li Feng, Shayna Sandhaus, Gagandeep Narula, Dianqing Sun, Lissa S. Tsutsumi, Xiaoqian Wu, Julian G. Hurdle, Marcus M. Maddox, David F. Bruhn, Richard E. Lee, Zahidul Alam, Robin B. Lee
Publikováno v:
Journal of Medicinal Chemistry
On the basis of recently reported abyssinone II and olympicin A, a series of chemically modified flavonoid phytochemicals were synthesized and evaluated against Mycobacterium tuberculosis and a panel of Gram-positive and -negative bacterial pathogens
Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux
Autor:
Julian G. Hurdle, Rashid Akbergenov, Cristina Villellas, José A. Aínsa, Michael R. McNeil, Robin B. Lee, Jiuyu Liu, Dora B. Madhura, Erik C. Böttger, Rakesh, Zhong Zheng, Richard E. Lee, Bernd Meibohm, Pavan K. Vaddady, Jianjun Qi, Sourav Das, Samanthi L. Waidyarachchi, David F. Bruhn, Helena I. Boshoff, Michael S. Scherman, Dianqing Sun, Mercedes Gonzalez-Juarrero, Tanja Matt, Chetan Rathi, Anne J. Lenaerts, Ashit Trivedi
Publikováno v:
Nature medicine
Although the classical antibiotic spectinomycin is a potent bacterial protein synthesis inhibitor, poor antimycobacterial activity limits its clinical application for treating tuberculosis. Using structure-based design, we generated a new semisynthet