Zobrazeno 1 - 10
of 93
pro vyhledávání: '"David F. Barker"'
Autor:
Diana Avila, Jingwen Zhang, Shirish Barve, Leila Gobejishvili, Craig J. McClain, David F. Barker
Publikováno v:
The Journal of Pathology. 240:96-107
Alcohol-induced hepatic steatosis is a significant risk factor for progressive liver disease. Cyclic adenosine monophosphate (cAMP) signalling has been shown to significantly regulate lipid metabolism; however, the role of altered cAMP homeostasis in
Autor:
Daniell B. Hill, David F. Barker, Craig J. McClain, Alexander C. Cambon, Shirish Barve, Leila Gobejishvili, Rehan Khan, Smita Ghare
Publikováno v:
Clinical Immunology. 161:291-299
Dysregulated cytokine metabolism plays a critical role in the pathogenesis of many forms of liver disease, including alcoholic and non-alcoholic liver disease. In this study we examined the efficacy of Misoprostol in modulating LPS-inducible TNFα an
Autor:
Christie J. Rizzo, Larry K. Brown, David F. Barker, Caron Zlotnick, Meredith C. Joppa, Charlene Collibee
Publikováno v:
Prevention science : the official journal of the Society for Prevention Research. 19(4)
This study assessed the initial feasibility, acceptability, and efficacy of an intervention aimed at reducing dating violence and sexual risk behavior in a sample of adolescent girls (ages 14–17) with prior exposure to physical dating violence (DV)
Autor:
Leila Gobejishvili, Swati Joshi-Barve, Smita Ghare, Jingwen Zhang, Craig J. McClain, Irina A. Kirpich, Giorgi Kharebava, Shirish Barve, David F. Barker
Publikováno v:
Alcoholism: Clinical and Experimental Research. 37:1920-1929
Background: Recently, we have demonstrated that acute alcohol exposure due to binge drinking leads to hepatic steatosis with the deregulation of hepatic histone deacetylase (HDAC) expression. Various class I, II, and IV HDACs were down-regulated, whe
Autor:
Swati Joshi-Barve, Shirish Barve, David F. Barker, Craig J. McClain, Hridgandh Donde, Wei-Yang Chen, Smita Ghare, Leila Gobejishvilli
Zidovudine (AZT) remains the mainstay of antiretroviral therapy against HIV in resource-poor countries; however, its use is frequently associated with hepatotoxicity. Not all HIV patients on AZT develop hepatotoxicity, and the determining factors are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bf5bbf2161b804c1ba31f852f5d59a
https://europepmc.org/articles/PMC4938746/
https://europepmc.org/articles/PMC4938746/
Autor:
Diana V, Avila, David F, Barker, JingWen, Zhang, Craig J, McClain, Shirish, Barve, Leila, Gobejishvili
Publikováno v:
The Journal of pathology. 240(1)
Alcohol-induced hepatic steatosis is a significant risk factor for progressive liver disease. Cyclic adenosine monophosphate (cAMP) signalling has been shown to significantly regulate lipid metabolism; however, the role of altered cAMP homeostasis in
Autor:
David F. Barker, Shirish Barve, Craig J. McClain, Wenke Feng, Irina A. Kirpich, Yuhua Wang, Yanlong Liu
Publikováno v:
Alcoholism: Clinical and Experimental Research. 36:835-846
Background Interactions between the gut, immune system, and the liver, as well as the type of fat in the diet, are critical components of alcoholic liver disease (ALD). The goal of the present study was to determine the effects of saturated and unsat
Autor:
Swati Joshi-Barve, David Henderson, David F. Barker, Guy N. Brock, Irina A. Kirpich, Sri Prakash Mokshagundam, Smita Ghare, Shirish Barve, Craig J. McClain, Diana Avila, Leila Gobejishvili
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 337:433-443
S-Adenosylmethionine (SAM) treatment has anti-inflammatory, cytoprotective effects against endotoxin-induced organ injury. An important component of the anti-inflammatory action of SAM involves down-regulation of the lipopolysaccharide (LPS)-induced
Autor:
Marc K. Drezner, Peggy A. Becker, Marcy C. Speer, Pamela R. Fain, Michael J. Econs, Arlene Taylor, Michael Norman, Margaret A. Pericak-Vance, David F. Barker
Publikováno v:
Journal of Bone and Mineral Research. 8:1149-1152
X-linked hypophosphatemic rickets (HYP) is an X-linked dominant disorder characterized by decreased renal tubular phosphate reabsorption and consequent hypophosphatemia. The defect in tubular phosphate reabsorption is probably secondary to an unident
Autor:
Qiahong Liu, Mark A. Doll, David F. Barker, Yan Li, David W. Hein, Robert C.G. Martin, Neil S. Jensen
Publikováno v:
DNA and Cell Biology. 28:3-7
Mitochondrial manganese superoxide dismutase (MnSOD), encoded by the SOD2 gene, represents a major cellular defense against environmental carcinogens that cause oxidative stress. Two single-nucleotide polymorphisms −9 T>C (V16A in the MnSOD mitocho