Zobrazeno 1 - 10
of 23
pro vyhledávání: '"David F. Allison"'
Autor:
Szymon J. Szymura, Jacob P. Zaemes, David F. Allison, Sheena H. Clift, Jaclyn M. D’Innocenzi, Lisa G. Gray, Brian D. McKenna, Benjamin B. Morris, Stefan Bekiranov, Robin D. LeGallo, David R. Jones, Marty W. Mayo
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background Epithelial-to-mesenchymal transition (EMT) results in changes that promote de-differentiation, migration, and invasion in non-small cell lung cancer (NSCLC). While it is recognized that EMT promotes altered energy utilization, ide
Externí odkaz:
https://doaj.org/article/8a7d2385b8c4479986c791fd365218ee
Autor:
Bowen Xu, Ling Cai, Jason M. Butler, Dongliang Chen, Xiongdong Lu, David F. Allison, Rui Lu, Shahin Rafii, Joel S. Parker, Deyou Zheng, Gang Greg Wang
Publikováno v:
Stem Cell Reports, Vol 10, Iss 3, Pp 675-683 (2018)
Summary: Self-renewal and differentiation of adult stem cells are tightly regulated partly through configuration of chromatin structure by chromatin remodelers. Using knockout mice, we here demonstrate that bromodomain PHD finger transcription factor
Externí odkaz:
https://doaj.org/article/68b649dbacad4069b98f371a76ed6495
Autor:
Zhi-Min Zhang, Scott B. Rothbart, David F. Allison, Qian Cai, Joseph S. Harrison, Lin Li, Yinsheng Wang, Brian D. Strahl, Gang Greg Wang, Jikui Song
Publikováno v:
Cell Reports, Vol 12, Iss 9, Pp 1400-1406 (2015)
The protein stability and chromatin functions of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) are regulated in a cell-cycle-dependent manner. We report a structural characterization of the complex between UHRF1 and the deubiquiti
Externí odkaz:
https://doaj.org/article/21ed9dd243ab4df5a043803a22ccbf0d
Autor:
Marty W. Mayo, Stefan Bekiranov, David R. Jones, Christopher A. Moskaluk, Xiaojiang Xu, Stephen A. Hoang, Szymon J. Szymura, Caitlyn M. Holzknecht, Sheena H. Clift, David F. Allison, Manish Kumar, J. Jacob Wamsley
Soluble growth factors and cytokines within the tumor microenvironment aid in the induction of the epithelial-to-mesenchymal transition (EMT). Although EMT promotes the development of cancer-initiating cells (CIC), cellular mechanisms by which cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::267489785277719de60f9e138d406cd9
https://doi.org/10.1158/0008-5472.c.6505958
https://doi.org/10.1158/0008-5472.c.6505958
Autor:
Marty W. Mayo, Stefan Bekiranov, David R. Jones, Christopher A. Moskaluk, Xiaojiang Xu, Stephen A. Hoang, Szymon J. Szymura, Caitlyn M. Holzknecht, Sheena H. Clift, David F. Allison, Manish Kumar, J. Jacob Wamsley
Supplemental Table 1 and 2 and Supplemental Figure 1-5. Supplemental Table 1: Oligonucleotide sequences of shRNA molecules targeting INHBA/Activin and the targeted sequences. Supplemental Table 2: Oligonucleotide sequences used for amplification in Q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0543e0fa7d723617f81ee210cca2f259
https://doi.org/10.1158/0008-5472.22401968
https://doi.org/10.1158/0008-5472.22401968
Autor:
Jun Wang, Xufen Yu, Weida Gong, Xijuan Liu, Kwang-Su Park, Anqi Ma, Yi-Hsuan Tsai, Yudao Shen, Takashi Onikubo, Wen-Chieh Pi, David F. Allison, Jing Liu, Wei-Yi Chen, Ling Cai, Robert G. Roeder, Jian Jin, Gang Greg Wang
Publikováno v:
Nat Cell Biol
Canonically, EZH2 serves as the catalytic subunit of PRC2, which mediates H3K27me3 deposition and transcriptional repression. Here, we report that in acute leukaemias, EZH2 has additional noncanonical functions by binding cMyc at non-PRC2 targets and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e39fbbf27c4719eb520e72f58ac8850
https://doi.org/10.1038/s41556-022-00850-x
https://doi.org/10.1038/s41556-022-00850-x
Autor:
Jeong Hyun Ahn, Shenghui He, David F. Allison, Huitao Fan, Jikui Song, Jiuwei Lu, Ling Cai, Wen Chieh Pi, Yarui Diao, Zhi-Min Zhang, Huimin Geng, Dongxu Li, Yu Xiang, Weida Gong, Gang Greg Wang, Yi-Hsuan Tsai, Brian D. Strahl, Wei Yi Chen, Yiran Guo
Publikováno v:
Nat Genet
Nature genetics, vol 52, iss 12
Nature genetics, vol 52, iss 12
Trimethylated histone H3 lysine 27 (H3K27me3) regulates gene repression, cell-fate determination and differentiation. We report that a conserved bromo-adjacent homology (BAH) module of BAHCC1 (BAHCC1BAH) 'recognizes' H3K27me3 specifically and enforce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7cf7802ec408a049e41355a991ef6c
https://doi.org/10.1038/s41588-020-00729-3
https://doi.org/10.1038/s41588-020-00729-3
Autor:
Robin D. LeGallo, Marty W. Mayo, Lisa G. Gray, Jaclyn M. D’Innocenzi, Sheena H. Clift, Szymon J. Szymura, Stefan Bekiranov, David R. Jones, Brian D. McKenna, David F. Allison, Benjamin B. Morris, Jacob P. Zaemes
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-16 (2019)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background Epithelial-to-mesenchymal transition (EMT) results in changes that promote de-differentiation, migration, and invasion in non-small cell lung cancer (NSCLC). While it is recognized that EMT promotes altered energy utilization, identificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7886feea351ed405d5c17b4358ec6cca
http://link.springer.com/article/10.1186/s12964-019-0335-5
http://link.springer.com/article/10.1186/s12964-019-0335-5
Autor:
Rui Lu, Shahin Rafii, Jason M. Butler, Dongliang Chen, Bowen Xu, David F. Allison, Ling Cai, Gang Greg Wang, Deyou Zheng, Joel S. Parker, Xiongdong Lu
Publikováno v:
Stem Cell Reports, Vol 10, Iss 3, Pp 675-683 (2018)
Stem Cell Reports
Stem Cell Reports
Summary Self-renewal and differentiation of adult stem cells are tightly regulated partly through configuration of chromatin structure by chromatin remodelers. Using knockout mice, we here demonstrate that bromodomain PHD finger transcription factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bb420e08fddf9786722d5a9450b1a5
https://doi.org/10.1016/j.stemcr.2018.01.020
https://doi.org/10.1016/j.stemcr.2018.01.020
Autor:
David F. Allison, Gang Greg Wang
Publikováno v:
Cell Stress
Cell Stress, Vol 3, Iss 2, Pp 38-47 (2019)
Cell Stress, Vol 3, Iss 2, Pp 38-47 (2019)
Exposure of genomic, single-stranded DNA (ssDNA) during transcription and replication creates opportunities for the formation of inappropriate secondary structures. Cells manage this exposure by using topoisomerases and helicases to reduce the inhere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f006b160826385eb523a170da01b6e
https://pubmed.ncbi.nlm.nih.gov/31225499
https://pubmed.ncbi.nlm.nih.gov/31225499