Zobrazeno 1 - 10
of 212
pro vyhledávání: '"David F Stern"'
Autor:
Michael I Klein, Vincent L Cannataro, Jeffrey P Townsend, Scott Newman, David F Stern, Hongyu Zhao
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 3, Pp n/a-n/a (2021)
Abstract Identifying cooperating modules of driver alterations can provide insights into cancer etiology and advance the development of effective personalized treatments. We present Cancer Rule Set Optimization (CRSO) for inferring the combinations o
Externí odkaz:
https://doaj.org/article/6019ff0ef7ef483ab82c56178e4ef11f
Autor:
Kaitlyn M Gayvert, Omar Aly, James Platt, Marcus W Bosenberg, David F Stern, Olivier Elemento
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 1, p e1005308 (2017)
A promising alternative to address the problem of acquired drug resistance is to rely on combination therapies. Identification of the right combinations is often accomplished through trial and error, a labor and resource intensive process whose scale
Externí odkaz:
https://doaj.org/article/b51c1429d0444d8a8a38da999face423
Autor:
Yalai Bai, Huan Cheng, Jennifer Bordeaux, Veronique Neumeister, Sudha Kumar, David L Rimm, David F Stern
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79901 (2013)
HER2/Neu (ErbB-2) overexpression, which occurs in 15-20% of breast cancer cases, is associated with better response to treatment with the drug trastuzumab. PhosphoHER2 (pHER2) has been evaluated for prediction of response to trastuzumab. Both markers
Externí odkaz:
https://doaj.org/article/120a4aeb316c45a5a4f081c211f4e8c9
Autor:
David F. Stern, Howard S. Hochster, Christos Hatzis, Ja Seok Koo, Jong Woo Lee, Matthew A. Held, Michael Klein, Ramanaiah Mamillapalli, Pinar Iyidogan, Robert E. Means, James T. Platt, Casey G. Langdon
Pairwise similarities of Yale, GDSC and CCLE datasets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019211ba1cc80dd5a28fb0d9390b87e3
https://doi.org/10.1158/1535-7163.22509253.v1
https://doi.org/10.1158/1535-7163.22509253.v1
Autor:
Marcus W. Bosenberg, David F. Stern, Richard A. Scolyer, Georgina V. Long, Goran Micevic, Katrina M. Meeth, Alexander Marzuka-Alcala, Matthew A. Held, Nicholas Theodosakis
BRAF kinase inhibitors have dramatically affected treatment of BRAFV600E/K-driven metastatic melanoma. Early responses assessed using [18F]fluorodeoxyglucose uptake-positron emission tomography (FDG-PET) have shown dramatic reduction of radiotracer s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5f41ce50384eb3dfebaf45da23b722
https://doi.org/10.1158/1535-7163.c.6537120
https://doi.org/10.1158/1535-7163.c.6537120
Autor:
David F. Stern, Marcus W. Bosenberg, Jonathan W. Haskins, Andrew Koo, Antonella Bacchiocchi, Ashok Chakraborty, Zongzhi Liu, Tisheeka Graham-Steed, James T. Platt, Casey G. Langdon, Matthew A. Held
XLSX file - 134K, Table S8. Most effective genotype-selective combinations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04dc85300f037ae5553db92c07acd09
https://doi.org/10.1158/2159-8290.22528703
https://doi.org/10.1158/2159-8290.22528703
Autor:
David F. Stern, Marcus W. Bosenberg, Jonathan W. Haskins, Andrew Koo, Antonella Bacchiocchi, Ashok Chakraborty, Zongzhi Liu, Tisheeka Graham-Steed, James T. Platt, Casey G. Langdon, Matthew A. Held
PDF file - 1.1MB, Figure S1. Single agent concentration-effect curves, related to Figure 1; Figure S2. Drug class and concentration choices for combinatorial drug screening, related to Figure 2; Figure S3, Mutant BRAF and mutant RAS selective drug pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eae7527ca5c5d876d8e33fa33b99f5d
https://doi.org/10.1158/2159-8290.22528706.v1
https://doi.org/10.1158/2159-8290.22528706.v1
Autor:
David F. Stern, Zongzhi Liu, James T. Platt, Maureen Gilmore-Hebert, Jonathan W. Haskins, Vikram B. Wali
XLSX file - 60KB, Predicted activation of Transcriptional regulators.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143febaa9ad3c9affcdda0a0d03fbe95
https://doi.org/10.1158/1541-7786.22514173.v1
https://doi.org/10.1158/1541-7786.22514173.v1
Autor:
Marcus W. Bosenberg, David F. Stern, Richard A. Scolyer, Georgina V. Long, Goran Micevic, Katrina M. Meeth, Alexander Marzuka-Alcala, Matthew A. Held, Nicholas Theodosakis
Supplemental Figure 7. Changes in signaling upstream of translation initiation complex assembly within 24 hours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071377e08767f3cd099bc682e219a9c5
https://doi.org/10.1158/1535-7163.22502550.v1
https://doi.org/10.1158/1535-7163.22502550.v1
Autor:
David F. Stern, Zongzhi Liu, James T. Platt, Maureen Gilmore-Hebert, Jonathan W. Haskins, Vikram B. Wali
XLSX file - 42KB, Canonical pathways altered by FL and ICD ERBB4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab84a726b6aa1f16ec0c0f126db3135
https://doi.org/10.1158/1541-7786.22514176.v1
https://doi.org/10.1158/1541-7786.22514176.v1