Zobrazeno 1 - 10
of 238
pro vyhledávání: '"David F Garway-Heath"'
Autor:
Naushin H Waseem, Sancy Low, Amna Z Shah, Deepa Avisetti, Pia Ostergaard, Michael Simpson, Katarzyna A Niemiec, Belen Martin-Martin, Hebah Aldehlawi, Saima Usman, Pak Sang Lee, Anthony P Khawaja, Jonathan B Ruddle, Ameet Shah, Ege Sackey, Alexander Day, Yuzhen Jiang, Geoff Swinfield, Ananth Viswanathan, Giovanna Alfano, Christina Chakarova, Heather J Cordell, David F Garway-Heath, Peng T Khaw, Shomi S Bhattacharya, Ahmad Waseem, Paul J Foster
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008721 (2020)
Current estimates suggest 50% of glaucoma blindness worldwide is caused by primary angle-closure glaucoma (PACG) but the causative gene is not known. We used genetic linkage and whole genome sequencing to identify Spermatogenesis Associated Protein 1
Externí odkaz:
https://doaj.org/article/d5c95c4f9b2048b1a0b64b97787b4d40
Autor:
David F Garway-Heath, Haogang Zhu, Qian Cheng, Katy Morgan, Chris Frost, David P Crabb, Tuan-Anh Ho, Yannis Agiomyrgiannakis
Publikováno v:
Health Technology Assessment, Vol 22, Iss 4 (2018)
Background: Progressive optic nerve damage in glaucoma results in vision loss, quantifiable with visual field (VF) testing. VF measurements are, however, highly variable, making identification of worsening vision (‘progression’) challenging. Glau
Externí odkaz:
https://doaj.org/article/17852d13b0144711984cf747fa832943
Autor:
David P Crabb, Richard A Russell, Rizwan Malik, Nitin Anand, Helen Baker, Trishal Boodhna, Carol Bronze, Simon SM Fung, David F Garway-Heath, Fiona C Glen, Rodolfo Hernández, James F Kirwan, Claire Lemer, Andrew I McNaught, Ananth C Viswanathan
Publikováno v:
Health Services and Delivery Research, Vol 2, Iss 27 (2014)
Background: Visual field (VF) tests are the benchmark for detecting and monitoring the eye disease glaucoma. Measurements from VF tests are variable, which means that frequent monitoring, perhaps over a long period of time, is required to accurately
Externí odkaz:
https://doaj.org/article/7685aee10949490c86829053e8f55614
Autor:
Haogang Zhu, Richard A Russell, Luke J Saunders, Stefano Ceccon, David F Garway-Heath, David P Crabb
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85654 (2014)
Visual fields measured with standard automated perimetry are a benchmark test for determining retinal function in ocular pathologies such as glaucoma. Their monitoring over time is crucial in detecting change in disease course and, therefore, in prom
Externí odkaz:
https://doaj.org/article/e47684cee2784a809e3c899618646140
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83595 (2013)
ObjectiveTo develop a model to simulate visual fields (VFs) in glaucoma patients, and to characterize variability of the Mean Deviation (MD) VF summary measurement using real VFs and simulations.MethodsPointwise VF variability was previously approxim
Externí odkaz:
https://doaj.org/article/fbf3664d8a864f659549f25ab9a42021
Autor:
David P Crabb, Nicholas D Smith, Franziska G Rauscher, Catharine M Chisholm, John L Barbur, David F Edgar, David F Garway-Heath
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9710 (2010)
BACKGROUND: Glaucoma is a progressive eye disease and a leading cause of visual disability. Automated assessment of the visual field determines the different stages in the disease process: it would be desirable to link these measurements taken in the
Externí odkaz:
https://doaj.org/article/b41060cf91b645cfa5b99aebc002fc2f
Autor:
Xiaoqin Huang, Jian Sun, Krati Gupta, Giovanni Montesano, David P. Crabb, David F. Garway-Heath, Paolo Brusini, Paolo Lanzetta, Francesco Oddone, Andrew Turpin, Allison M. McKendrick, Chris A. Johnson, Siamak Yousefi
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
ObjectiveTo assess the accuracy of probabilistic deep learning models to discriminate normal eyes and eyes with glaucoma from fundus photographs and visual fields.DesignAlgorithm development for discriminating normal and glaucoma eyes using data from
Externí odkaz:
https://doaj.org/article/933aa426777248e59920df3af0d40b0b
Autor:
Dimitrios Stavropoulos, Manjot K. Grewal, Bledi Petriti, Kai-Yin Chau, Christopher J. Hammond, David F. Garway-Heath, Gerassimos Lascaratos
Publikováno v:
Cells, Vol 12, Iss 15, p 1969 (2023)
This review aims to provide a better understanding of the emerging role of mitophagy in glaucomatous neurodegeneration, which is the primary cause of irreversible blindness worldwide. Increasing evidence from genetic and other experimental studies su
Externí odkaz:
https://doaj.org/article/8bc23e92ecfd497988c6ec2e38382006
Autor:
Juliane Matlach, Padraig Mulholland, Marketa Cilkova, Reena Chopra, Nilpa Shah, Tony Redmond, Steven C Dakin, David F Garway-Heath, Roger S Anderson
Publikováno v:
European Journal of Ophthalmology. 33:1434-1442
Purpose To investigate age-related changes of the outer nuclear layer (ONL) thickness and cone density, and their associations in healthy participants using a modified, narrow scan-angle Heidelberg Retina Angiograph (HRA2). Methods Retinal cones were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e3353ef79463b7bc7ef4d952c372f0
https://doi.org/10.1177/11206721221144477
https://doi.org/10.1177/11206721221144477
Publikováno v:
Cells, Vol 10, Iss 6, p 1402 (2021)
Glaucoma is the leading cause of irreversible blindness worldwide. Its prevalence and incidence increase exponentially with age and the level of intraocular pressure (IOP). IOP reduction is currently the only therapeutic modality shown to slow glauco
Externí odkaz:
https://doaj.org/article/03e43154856e494eb0f67f5666729d6c