Zobrazeno 1 - 10
of 280
pro vyhledávání: '"David F Callen"'
Autor:
Feng Yu, Cameron P Bracken, Katherine A Pillman, David M Lawrence, Gregory J Goodall, David F Callen, Paul M Neilsen
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129190 (2015)
p53 is a master tumour repressor that participates in vast regulatory networks, including feedback loops involving microRNAs (miRNAs) that regulate p53 and that themselves are direct p53 transcriptional targets. We show here that a group of polycistr
Externí odkaz:
https://doaj.org/article/2fcaf17e2a1b41d0abe99d5e1d6c7f57
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
GSK-LSD1, Doxorubicin and AraC have no effect on KDM1A and KDM1B expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1051ce09797e7b498c067f204794a86
https://doi.org/10.1158/1535-7163.22509571.v1
https://doi.org/10.1158/1535-7163.22509571.v1
Autor:
Benjamin Solomon, Grant A. McArthur, Wolfgang Hackl, Sauveur-Michel Maira, David F. Callen, Paul M. Neilsen, Anthony Natoli, Carleen Cullinane, Susan Jackson, Arun Azad
PDF file - 43K, BEZ235 inhibits phosphorylation of PI3K/mTOR. Western blot showing phospho-AKT (Ser473) and phospho-S6 (Ser235/236) expression in serum-starved H460 and A549 cells treated with indicated doses of BEZ235 and stimulated with IGF-1 (100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d667031972cf26a484f8f47aa239d92
https://doi.org/10.1158/1541-7786.22519450
https://doi.org/10.1158/1541-7786.22519450
Autor:
Benjamin Solomon, Grant A. McArthur, Wolfgang Hackl, Sauveur-Michel Maira, David F. Callen, Paul M. Neilsen, Anthony Natoli, Carleen Cullinane, Susan Jackson, Arun Azad
PDF file - 1.8MB, BEZ235 does not induce abnormal mitoses in irradiated H460 and A549 cells. Number of abnormal mitoses at 48 hours following indicated treatment. An average of 70 cells per group was counted to determine mean +/- SEM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d7d49704002f3a518761702519ff53
https://doi.org/10.1158/1541-7786.22519441
https://doi.org/10.1158/1541-7786.22519441
Autor:
Benjamin Solomon, Grant A. McArthur, Wolfgang Hackl, Sauveur-Michel Maira, David F. Callen, Paul M. Neilsen, Anthony Natoli, Carleen Cullinane, Susan Jackson, Arun Azad
PDF file - 85K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f869f640f0c3fd7edf403d84352fe2
https://doi.org/10.1158/1541-7786.22519423
https://doi.org/10.1158/1541-7786.22519423
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
Protein expression of ER-stress response genes following treatment with SP-2509
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0388e4ca3b246780959d79b84a856ff2
https://doi.org/10.1158/1535-7163.22509565.v1
https://doi.org/10.1158/1535-7163.22509565.v1
Autor:
Benjamin Solomon, Grant A. McArthur, Wolfgang Hackl, Sauveur-Michel Maira, David F. Callen, Paul M. Neilsen, Anthony Natoli, Carleen Cullinane, Susan Jackson, Arun Azad
PDF file - 2MB, IL-8, MIF and PAI-1 levels in supernatant from H460 and A549 cells after 96 hours treatment. Supernatant volumes were normalized to cell number and analyzed using cytokine antibody arrays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950516d8c5f966ed8e8b069c6ab77a3a
https://doi.org/10.1158/1541-7786.22519438.v1
https://doi.org/10.1158/1541-7786.22519438.v1
Autor:
Benjamin Solomon, Grant A. McArthur, Wolfgang Hackl, Sauveur-Michel Maira, David F. Callen, Paul M. Neilsen, Anthony Natoli, Carleen Cullinane, Susan Jackson, Arun Azad
PDF file - 4.6MB, Representative immunofluorescence images of phospho-ATM (Ser1981) foci in H460 and A549 cells at 30 minutes after 10 Gy dose of radiation (x 60 magnification). Green, phospho-ATM foci. Blue, DAPI staining.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf40121ec48dd668ec4e031c244d61a
https://doi.org/10.1158/1541-7786.22519432.v1
https://doi.org/10.1158/1541-7786.22519432.v1
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
Targeted KDM1A inhibition and EWS/FLI knockdown induces similar transcriptional signatures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43708ed7fd5e4213822a969dd241bbbf
https://doi.org/10.1158/1535-7163.22509577
https://doi.org/10.1158/1535-7163.22509577
Autor:
Benjamin Solomon, Grant A. McArthur, Wolfgang Hackl, Sauveur-Michel Maira, David F. Callen, Paul M. Neilsen, Anthony Natoli, Carleen Cullinane, Susan Jackson, Arun Azad
PDF file - 7.4MB, TUNEL assay in H460 and A549 cells after 48 hours treatment. H460 cells irradiated with 20 Gy were used as a positive control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650ecdeb19267823b5c4969a5d4f14d2
https://doi.org/10.1158/1541-7786.22519444
https://doi.org/10.1158/1541-7786.22519444